{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T04:35:16Z","timestamp":1784608516683,"version":"3.55.0"},"reference-count":28,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"7","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2018,4,3]]},"abstract":"<jats:sec xml:lang=\"en\">\n            <jats:title>Background<\/jats:title>\n            <jats:p xml:lang=\"en\">Medication adherence improves outcomes for patients with heart failure, but adherence rates remain low. We examined the association between earlier postdischarge follow\u2010up and medication adherence.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Methods and Results<\/jats:title>\n            <jats:p xml:lang=\"en\">We performed a retrospective cohort study of patients \u226565\u00a0years who were hospitalized for heart failure, covered by Medicare Part D, and discharged alive from April 2006 to October 2012 using the Get With The Guidelines\u2010Heart Failure Registry linked to Medicare claims. Patients were categorized into 4 groups by timing of first postdischarge follow\u2010up visit: \u22641, 1 to 2, 2 to 6, and &gt;6\u00a0weeks. Medication adherence was defined by proportion of days covered of &gt;80% at 90\u00a0days and 1\u2010year posthospital discharge to 5 guideline\u2010directed medical therapies (angiotensin\u2010converting enzyme inhibitor\/angiotensin receptor blocker, evidence\u2010based \u03b2\u2010blocker, aldosterone antagonist, hydralazine\/isosorbide dinitrate, and anticoagulation for atrial fibrillation). Among 9878 patients with heart failure, 73% had left ventricular ejection fraction \u226440%, median age was 78\u00a0years (25th\u201375th percentile, 71\u201384), and 48% were male. Overall, 30% had a follow\u2010up appointment within 1\u2010week postdischarge and 25% &gt;6\u00a0weeks. At 1\u00a0year, medication adherence was 53% for evidence\u2010based \u03b2\u2010blockers, 48% for angiotensin\u2010converting enzyme inhibitors\/angiotensin receptor blockers, and 8% for hydralazine\/isosorbide dinitrate. We found no significant association between timing of first follow\u2010up visit and medication adherence at 1\u00a0year (1.04, 0.92\u20131.17) when comparing follow\u2010up visits &gt;6\u00a0weeks to the earliest ones.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p xml:lang=\"en\">Posthospital heart failure discharge, overall adherence to medical therapies in Medicare beneficiaries was low. Early follow\u2010up was not associated with increased medication adherence to guideline\u2010directed medical therapy in the short or long term.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/jaha.117.007998","type":"journal-article","created":{"date-parts":[[2018,4,1]],"date-time":"2018-04-01T09:05:12Z","timestamp":1522573512000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":23,"title":["Timing of Postdischarge Follow\u2010Up and Medication Adherence Among Patients With Heart Failure"],"prefix":"10.1161","volume":"7","author":[{"given":"Leslie L.","family":"Chang","sequence":"first","affiliation":[{"name":"Department of Medicine, Duke University School of Medicine, Durham, NC"},{"name":"Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haolin","family":"Xu","sequence":"additional","affiliation":[{"name":"Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam D.","family":"DeVore","sequence":"additional","affiliation":[{"name":"Department of Medicine, Duke University School of Medicine, Durham, NC"},{"name":"Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roland A.","family":"Matsouaka","sequence":"additional","affiliation":[{"name":"Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC"},{"name":"Department of Biostatistics and Bioinformatics, Duke University, Durham, NC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clyde W.","family":"Yancy","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Northwestern University Feinberg School of Medicine, Chicago, IL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregg C.","family":"Fonarow","sequence":"additional","affiliation":[{"name":"Ahmanson\u2010UCLA Cardiomyopathy Center, University of California, Los Angeles, CA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Larry A.","family":"Allen","sequence":"additional","affiliation":[{"name":"Division of Cardiology, University of Colorado School of Medicine, Aurora, CO"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adrian F.","family":"Hernandez","sequence":"additional","affiliation":[{"name":"Department of Medicine, Duke University School of Medicine, Durham, NC"},{"name":"Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_5_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000435"},{"key":"e_1_3_5_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardfail.2011.04.011"},{"key":"e_1_3_5_4_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.115.014281"},{"key":"e_1_3_5_5_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0b013e31829e8776"},{"key":"e_1_3_5_6_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2010.533"},{"key":"e_1_3_5_7_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamacardio.2016.0001"},{"key":"e_1_3_5_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2004.09.015"},{"key":"e_1_3_5_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.hpc.0000243588.00012.79"},{"key":"e_1_3_5_10_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.0000435779.48007.5c"},{"key":"e_1_3_5_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2008.09.045"},{"key":"e_1_3_5_12_2","doi-asserted-by":"publisher","DOI":"10.1161\/circheartfailure.115.002344"},{"key":"e_1_3_5_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2009.04.002"},{"key":"e_1_3_5_14_2","first-page":"457","article-title":"Measuring concurrent adherence to multiple related medications","volume":"15","author":"Choudhry NK","year":"2009","unstructured":"Choudhry NK, Shrank WH, Levin RL, Lee JL, Jan SA, Brookhart MA, Solomon DH. 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