{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T02:02:59Z","timestamp":1773280979328,"version":"3.50.1"},"reference-count":17,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"7","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2018,4,3]]},"abstract":"\n Background<\/jats:title>\n \n Chronic obstructive pulmonary disease (\n COPD<\/jats:styled-content>\n ) patients are at increased risk of respiratory related complications after cardiac surgery. It is unclear whether transcatheter aortic valve replacement (\n TAVR<\/jats:styled-content>\n ) or surgical aortic valve replacement (\n SAVR<\/jats:styled-content>\n ) results in favorable outcomes among\n COPD<\/jats:styled-content>\n patients.\n <\/jats:p>\n <\/jats:sec>\n \n Methods and Results<\/jats:title>\n \n Patients were identified from the Nationwide Inpatient Sample database from 2011 to 2014. Patients with age \u226560,\n COPD<\/jats:styled-content>\n , and either went transarterial\n TAVR<\/jats:styled-content>\n or\n SAVR<\/jats:styled-content>\n were included in the analysis. A 1:1 propensity\u2010matched cohort was created to examine the outcomes. A matched pair of 1210\n TAVR<\/jats:styled-content>\n and 1208\n SAVR<\/jats:styled-content>\n patients was identified. Respiratory\u2010related complications such as tracheostomy (0.8% versus 5.8%; odds ratio [\n OR<\/jats:styled-content>\n ], 0.14;\n P<\/jats:italic>\n <0.001), acute respiratory failure (16.4% versus 23.7%;\n OR<\/jats:styled-content>\n , 0.63;\n P<\/jats:italic>\n =0.002), reintubation (6.5% versus 10.0%;\n OR<\/jats:styled-content>\n , 0.49;\n P<\/jats:italic>\n <0.001), and pneumonia (4.5% versus 10.1%;\n OR<\/jats:styled-content>\n , 0.41;\n P<\/jats:italic>\n <0.001) were significantly less frequent with\n TAVR<\/jats:styled-content>\n versus\n SAVR<\/jats:styled-content>\n . Use of noninvasive mechanical ventilation was similar between\n TAVR<\/jats:styled-content>\n and\n SAVR<\/jats:styled-content>\n (4.1% versus 4.8%;\n OR<\/jats:styled-content>\n , 0.84;\n P<\/jats:italic>\n =0.41). Non\u2010respiratory\u2010related complications, such as in\u2010hospital mortality (3.3% versus 4.2%;\n OR<\/jats:styled-content>\n , 0.64;\n P<\/jats:italic>\n =0.035), bleeding requiring transfusion (9.9% versus 21.7%;\n OR<\/jats:styled-content>\n , 0.38;\n P<\/jats:italic>\n <0.001), acute kidney injury (17.7% versus 25.3%;\n OR<\/jats:styled-content>\n , 0.63;\n P<\/jats:italic>\n <0.001), and acute myocardial infarction (2.4% versus 8.4%;\n OR<\/jats:styled-content>\n , 0.19;\n P<\/jats:italic>\n <0.001), were significantly less frequent with\n TAVR<\/jats:styled-content>\n than\n SAVR<\/jats:styled-content>\n . Cost ($56\u00a0099 versus $63\u00a0146;\n P<\/jats:italic>\n <0.001) and hospital stay (mean, 7.7 versus 13.0\u00a0days;\n P<\/jats:italic>\n <0.001) were also more favorable with\n TAVR<\/jats:styled-content>\n than\n SAVR<\/jats:styled-content>\n .\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n TAVR<\/jats:styled-content>\n portended significantly fewer respiratory\u2010related complications compared with\n SAVR<\/jats:styled-content>\n in\n COPD<\/jats:styled-content>\n patients.\n TAVR<\/jats:styled-content>\n may be a preferable mode of aortic valve replacement in\n COPD<\/jats:styled-content>\n patients.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1161\/jaha.117.008408","type":"journal-article","created":{"date-parts":[[2018,4,1]],"date-time":"2018-04-01T09:05:12Z","timestamp":1522573512000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":27,"title":["Is Transcatheter Aortic Valve Replacement Better Than Surgical Aortic Valve Replacement in Patients With Chronic Obstructive Pulmonary Disease? A Nationwide Inpatient Sample Analysis"],"prefix":"10.1161","volume":"7","author":[{"given":"Tomo","family":"Ando","sequence":"first","affiliation":[{"name":"Division of Cardiology, Wayne State University\/Detroit Medical Center, Detroit, MI"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oluwole","family":"Adegbala","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Englewood Hospital and Medical Center Seton Hall University\u2010Hackensack Meridian School of Medicine, Englewood, NJ"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emmanuel","family":"Akintoye","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Wayne State University\/Detroit Medical Center, Detroit, MI"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Said","family":"Ashraf","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Wayne State University\/Detroit Medical Center, Detroit, MI"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohit","family":"Pahuja","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Wayne State University\/Detroit Medical Center, Detroit, MI"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandros","family":"Briasoulis","sequence":"additional","affiliation":[{"name":"Divison of Cardiovascular Medicine, University of Iowa Hospitals and Clinics, Iowa City, IA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hisato","family":"Takagi","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Surgery, Shizuoka Medical Center, Shizuoka, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cindy L.","family":"Grines","sequence":"additional","affiliation":[{"name":"Division of Cardiology, North Shore University Hospital Hofstra Northwell School of Medicine, Manhasset, NY"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis","family":"Afonso","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Wayne State University\/Detroit Medical Center, Detroit, MI"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Theodore","family":"Schreiber","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Wayne State University\/Detroit Medical Center, Detroit, MI"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2011.02.026"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2013.06.008"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2014.01.432"},{"key":"e_1_3_3_5_2","first-page":"314","article-title":"Risk of aortic valve replacement in patients with aortic stenosis and chronic obstructive pulmonary disease","volume":"21","author":"Spoon DB","year":"2012","unstructured":"Spoon DB, Orszulak TA, Edell ES, Li Z, Nishimura RA. 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HSR Proc Intensive Care Cardiovasc Anesth. 2009;1:39\u201347.","journal-title":"HSR Proc Intensive Care Cardiovasc Anesth"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.acvd.2014.01.002"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cjca.2016.12.001"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2017.06.069"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2017.05.060"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2017.06.020"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2014.04.005"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2017.07.027"}],"container-title":["Journal of the American Heart Association"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/JAHA.117.008408","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T11:04:06Z","timestamp":1715598246000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/JAHA.117.008408"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4,3]]},"references-count":17,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2018,4,3]]}},"alternative-id":["10.1161\/JAHA.117.008408"],"URL":"https:\/\/doi.org\/10.1161\/jaha.117.008408","relation":{},"ISSN":["2047-9980"],"issn-type":[{"value":"2047-9980","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,4,3]]},"assertion":[{"value":"2018-01-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-01-26","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-04-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e008408"}}