{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T13:18:32Z","timestamp":1780579112865,"version":"3.54.1"},"reference-count":40,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"9","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2018,5]]},"abstract":"\n Background<\/jats:title>\n \n Atrial fibrillation (\n AF<\/jats:styled-content>\n ) prevalence is increasing, and body mass index (\n BMI<\/jats:styled-content>\n ) is a risk factor for\n AF<\/jats:styled-content>\n . However, sex differences in the impact of\n BMI<\/jats:styled-content>\n on\n AF<\/jats:styled-content>\n risk have not been fully elucidated.\n <\/jats:p>\n <\/jats:sec>\n \n Methods and Results<\/jats:title>\n \n Data from the fourth survey (1994\u20131995) of the Troms\u00f8 Study (Norway) were used to investigate the association of single\u2010measurement\n BMI<\/jats:styled-content>\n on future\n AF<\/jats:styled-content>\n risk. To analyze the influence of\n BMI<\/jats:styled-content>\n changes on\n AF<\/jats:styled-content>\n risk, data from individuals who attended the third and fourth study surveys were used.\n AF<\/jats:styled-content>\n diagnosis was derived from record linkage and end point adjudication. Cox regression analysis was conducted using fractional polynomials of\n BMI<\/jats:styled-content>\n and\n BMI<\/jats:styled-content>\n change with models adjusted for age, baseline\n BMI<\/jats:styled-content>\n (change analyses), risk factors, comorbidities, and antihypertensive medications.\n <\/jats:p>\n \n Data were available for 24\u00a0799 individuals from the fourth survey (mean age, 45.5\u00b114.2\u00a0years; 52.9% women). Over 15.7\u00b15.5\u00a0years, 811 women (6.2%) and 918 men (7.9%) developed\n AF<\/jats:styled-content>\n . In men, lower\n BMI<\/jats:styled-content>\n decreased\n AF<\/jats:styled-content>\n risk and higher\n BMI<\/jats:styled-content>\n increased risk (hazard ratios [95% confidence intervals] for\n BMI<\/jats:styled-content>\n 18 or 40\u00a0kg\/m\n 2<\/jats:sup>\n compared with 23\u00a0kg\/m\n 2<\/jats:sup>\n were 0.75 [0.70\u20130.81] and 4.42 [3.00\u20136.53], respectively). The same pattern was identified in women. Two surveys were attended by 14\u00a0652 individuals. In men and women, a decrease in\n BMI<\/jats:styled-content>\n over time was associated with decreased\n AF<\/jats:styled-content>\n risk and an increase in\n BMI<\/jats:styled-content>\n was associated with increased\n AF<\/jats:styled-content>\n risk.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n Within a population cohort,\n BMI<\/jats:styled-content>\n was positively associated with\n AF<\/jats:styled-content>\n risk. Change in\n BMI<\/jats:styled-content>\n over time influenced\n AF<\/jats:styled-content>\n risk in both men and women.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1161\/jaha.117.008414","type":"journal-article","created":{"date-parts":[[2018,4,19]],"date-time":"2018-04-19T09:05:12Z","timestamp":1524128712000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":28,"title":["Sex Differences in the Impact of Body Mass Index on the Risk of Future Atrial Fibrillation: Insights From the Longitudinal Population\u2010Based Troms\u00f8 Study"],"prefix":"10.1161","volume":"7","author":[{"given":"Jocasta","family":"Ball","sequence":"first","affiliation":[{"name":"Pre\u2010Clinical Disease and Prevention, Baker Heart and Diabetes Institute, Melbourne, Australia"},{"name":"School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maja\u2010Lisa","family":"L\u00f8chen","sequence":"additional","affiliation":[{"name":"Pre\u2010Clinical Disease and Prevention, Baker Heart and Diabetes Institute, Melbourne, Australia"},{"name":"Department of Community Medicine, UiT The Arctic University of Norway, Troms\u00f8, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tom","family":"Wilsgaard","sequence":"additional","affiliation":[{"name":"Department of Community Medicine, UiT The Arctic University of Norway, Troms\u00f8, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henrik","family":"Schirmer","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine, UiT The Arctic University of Norway, Troms\u00f8, Norway"},{"name":"Department of Clinical Medicine, University of Oslo, Norway"},{"name":"Department of Cardiology, Akershus University Hospital, L\u00f8renskog, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laila A.","family":"Hopstock","sequence":"additional","affiliation":[{"name":"Department of Health and Care Sciences, UiT The Arctic University of Norway, Troms\u00f8, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bente","family":"Morseth","sequence":"additional","affiliation":[{"name":"Department of Community Medicine, UiT The Arctic University of Norway, Troms\u00f8, Norway"},{"name":"School of Sport Sciences, UiT The Arctic University of Norway, Troms\u00f8, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ellisiv B.","family":"Mathiesen","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine, UiT The Arctic University of Norway, Troms\u00f8, Norway"},{"name":"Department of Neurology, University Hospital of North Norway, Troms\u00f8, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Inger","family":"Nj\u00f8lstad","sequence":"additional","affiliation":[{"name":"Department of Community Medicine, UiT The Arctic University of Norway, Troms\u00f8, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sweta","family":"Tiwari","sequence":"additional","affiliation":[{"name":"Department of Community Medicine, UiT The Arctic University of Norway, Troms\u00f8, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ekaterina","family":"Sharashova","sequence":"additional","affiliation":[{"name":"Department of Community Medicine, UiT The Arctic University of Norway, Troms\u00f8, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_5_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.113.005119"},{"key":"e_1_3_5_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2012.12.093"},{"key":"e_1_3_5_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(02)01236-6"},{"key":"e_1_3_5_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2005.10.057"},{"key":"e_1_3_5_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(10)62037-5"},{"key":"e_1_3_5_7_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2015-007859"},{"key":"e_1_3_5_8_2","volume-title":"Global Health Risks Mortality and Burden of Disease Attributable to Selected Major Risks","author":"World Health Organization","year":"2009","unstructured":"World Health Organization . 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