{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T16:42:35Z","timestamp":1787676155442,"version":"build-2784847793"},"reference-count":35,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"11","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2018,6,5]]},"abstract":"<jats:sec xml:lang=\"en\">\n            <jats:title>Background<\/jats:title>\n            <jats:p xml:lang=\"en\">We sought to identify patient and surgical factors associated with time to hospital discharge in patients undergoing complete repair for tetralogy of Fallot.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Methods and Results<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              We performed a prospective cohort study of patients with tetralogy of Fallot admitted for complete repair between May 1, 2012 and June 2, 2017 at Children's Hospital of Philadelphia with detailed demographic, clinical, and operative characteristics. The primary outcome was time to hospital discharge. Cox proportional hazards models were used to identify patient and operative predictors of time to hospital discharge. We enrolled 151 subjects, 62.8% male, 65.6% non\u2010Hispanic white, and 9.9% non\u2010Hispanic black. The median time to hospital discharge was 7\u00a0days (interquartile range 4, 12). Five patients died in the hospital, all of whom underwent tetralogy of Fallot repair beyond the neonatal period. Greater birth weight was associated with higher rate of hospital discharge (hazard ratio [\n              <jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content>\n              ]=1.35, 95% confidence interval (CI) =1.11, 1.64), while absent pulmonary valve versus pulmonary stenosis (\n              <jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content>\n              =0.27, 95%\n              <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n              =0.08, 0.91), pulmonary valve atresia versus pulmonary stenosis (\n              <jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content>\n              =0.57, 95%\n              <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n              =0.33, 0.97), presence of aortopulmonary collaterals (\n              <jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content>\n              =0.44, 95%\n              <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n              =0.24, 0.84), complete repair performed in the neonatal period (&lt;30\u00a0days of life) (\n              <jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content>\n              =0.45, 95%\n              <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n              =0.27, 0.75), more than 1 cardiopulmonary bypass run (\n              <jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content>\n              =0.33, 95%\n              <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n              =0.18, 0.61), and longer aortic cross\u2010clamp time (\n              <jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content>\n              [per 10\u00a0minutes]=0.88, 95%\n              <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n              =0.79, 0.97) were associated with lower rate of hospital discharge.\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p xml:lang=\"en\">Postoperative hospital stay after complete repair of tetralogy of Fallot is in part determined by patient and operative factors. Some (eg, surgical strategy for the symptomatic neonate) may be modifiable. These results may impact patient counseling, choice of surgical approach, and postoperative care.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/jaha.118.008719","type":"journal-article","created":{"date-parts":[[2018,5,16]],"date-time":"2018-05-16T09:15:16Z","timestamp":1526462116000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":40,"title":["Predictors of Length of Hospital Stay After Complete Repair for Tetralogy of Fallot: A Prospective Cohort Study"],"prefix":"10.1161","volume":"7","author":[{"given":"Laura","family":"Mercer\u2010Rosa","sequence":"first","affiliation":[{"name":"Division of Cardiology, Department of Pediatrics, Children's Hospital of Philadelphia, PA"},{"name":"Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Okan U.","family":"Elci","sequence":"additional","affiliation":[{"name":"Biostatistics and Data Management Core, Children's Hospital of Philadelphia, PA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grace","family":"DeCost","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Pediatrics, Children's Hospital of Philadelphia, PA"},{"name":"Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stacy","family":"Woyciechowski","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Pediatrics, Children's Hospital of Philadelphia, PA"},{"name":"Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharon M.","family":"Edman","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Pediatrics, Children's Hospital of Philadelphia, PA"},{"name":"Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chitra","family":"Ravishankar","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Pediatrics, Children's Hospital of Philadelphia, PA"},{"name":"Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher E.","family":"Mascio","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Pediatrics, Children's Hospital of Philadelphia, PA"},{"name":"Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven M.","family":"Kawut","sequence":"additional","affiliation":[{"name":"Department of Medicine and the Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth","family":"Goldmuntz","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Pediatrics, Children's Hospital of Philadelphia, PA"},{"name":"Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2013.11.008"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2009.08.058"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1177\/2150135111426732"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1067\/mpd.2002.125227"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(03)00183-5"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCOUTCOMES.111.963603"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2017.02.066"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-013-0670-z"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2012.12.028"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.116.004952"},{"key":"e_1_3_3_12_2","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1111\/j.2517-6161.1968.tb00724.x","article-title":"A general definition of residuals","volume":"30","author":"Cox DSE","year":"1968","unstructured":"Cox DSE. 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