{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T15:42:51Z","timestamp":1792510971950,"version":"4.5.0"},"reference-count":25,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"12","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2018,6,19]]},"abstract":"\n Background<\/jats:title>\n \n Whether ventricular arrhythmias (\n VAs<\/jats:styled-content>\n ) represent a feature of the adaptive changes of the athlete's heart remains elusive. We aimed to assess the prevalence, determinants, and underlying substrates of\n VAs<\/jats:styled-content>\n in young competitive athletes.\n <\/jats:p>\n <\/jats:sec>\n \n Method and Results<\/jats:title>\n \n We studied 288 competitive athletes (age range, 16\u201335\u00a0years; median age, 21 years) and 144 sedentary individuals matched for age and sex who underwent 12\u2010lead 24\u2010hour ambulatory electrocardiographic monitoring.\n VAs<\/jats:styled-content>\n were evaluated in terms of number, complexity (ie, couplet, triplet, or nonsustained ventricular tachycardia), exercise inducibility, and morphologic features. Twenty\u2010eight athletes (10%) and 13 sedentary individuals (11%) showed >10 isolated premature ventricular beats (\n PVB<\/jats:styled-content>\n s) or \u22651 complex\n VA<\/jats:styled-content>\n (\n P<\/jats:italic>\n =0.81). Athletes with >10 isolated\n PVB<\/jats:styled-content>\n s or \u22651 complex\n VA<\/jats:styled-content>\n were older (median age, 26 versus 20 years;\n P<\/jats:italic>\n =0.008) but did not differ with regard to type of sport, hours of training, and years of activity compared with the remaining athletes. All athletes with >10 isolated\n PVB<\/jats:styled-content>\n s or \u22651 complex\n VA<\/jats:styled-content>\n had a normal echocardiographic examination; 17 of them showing >500 isolated\n PVB<\/jats:styled-content>\n s, exercise\u2010induced\n PVB<\/jats:styled-content>\n s, and\/or complex\n VA<\/jats:styled-content>\n underwent additional cardiac magnetic resonance, which demonstrated nonischemic left ventricular late gadolinium enhancement in 3 athletes with right bundle branch block\n PVB<\/jats:styled-content>\n s morphologic features.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n The prevalence of >10 isolated\n PVB<\/jats:styled-content>\n s or \u22651 complex\n VA<\/jats:styled-content>\n at 24\u2010hour ambulatory electrocardiographic monitoring did not differ between young competitive athletes and sedentary individuals and was unrelated to type, intensity, and years of sports practice. An underlying myocardial substrate was uncommon and distinctively associated with right bundle branch block\n VA<\/jats:styled-content>\n morphologic features.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1161\/jaha.118.009171","type":"journal-article","created":{"date-parts":[[2018,6,9]],"date-time":"2018-06-09T05:15:11Z","timestamp":1528521311000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":68,"title":["Ventricular Arrhythmias in Young Competitive Athletes: Prevalence, Determinants, and Underlying Substrate"],"prefix":"10.1161","volume":"7","author":[{"given":"Alessandro","family":"Zorzi","sequence":"first","affiliation":[{"name":"Department of Cardiac, Thoracic and Vascular Sciences University of Padova Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuel","family":"De Lazzari","sequence":"additional","affiliation":[{"name":"Department of Cardiac, Thoracic and Vascular Sciences University of Padova Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giulio","family":"Mastella","sequence":"additional","affiliation":[{"name":"Department of Cardiac, Thoracic and Vascular Sciences University of Padova Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alice","family":"Niero","sequence":"additional","affiliation":[{"name":"Department of Cardiac, Thoracic and Vascular Sciences University of Padova Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Domenico","family":"Trovato","sequence":"additional","affiliation":[{"name":"Department of Cardiac, Thoracic and Vascular Sciences University of Padova Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Cipriani","sequence":"additional","affiliation":[{"name":"Department of Cardiac, Thoracic and Vascular Sciences University of Padova Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Peruzza","sequence":"additional","affiliation":[{"name":"Department of Cardiac, Thoracic and Vascular Sciences University of Padova Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonardo","family":"Portolan","sequence":"additional","affiliation":[{"name":"Department of Cardiac, Thoracic and Vascular Sciences University of Padova Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giampaolo","family":"Berton","sequence":"additional","affiliation":[{"name":"Department of Cardiac, Thoracic and Vascular Sciences University of Padova Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federco","family":"Sciacca","sequence":"additional","affiliation":[{"name":"Department of Cardiac, Thoracic and Vascular Sciences University of Padova Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saverio","family":"Tollot","sequence":"additional","affiliation":[{"name":"Department of Cardiac, Thoracic and Vascular Sciences University of Padova Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiara","family":"Palermo","sequence":"additional","affiliation":[{"name":"Department of Cardiac, Thoracic and Vascular Sciences University of Padova Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Bellu","sequence":"additional","affiliation":[{"name":"Division of Cardiology Policlinico Abano Terme Padova Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Flavio","family":"D'ascenzi","sequence":"additional","affiliation":[{"name":"Division of Cardiology Department of Medical Biotechnologies University of Siena Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denisa","family":"Muraru","sequence":"additional","affiliation":[{"name":"Department of Cardiac, Thoracic and Vascular Sciences University of Padova Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luigi Paolo","family":"Badano","sequence":"additional","affiliation":[{"name":"Department of Cardiac, Thoracic and Vascular Sciences University of Padova Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabino","family":"Iliceto","sequence":"additional","affiliation":[{"name":"Department of Cardiac, Thoracic and Vascular Sciences University of Padova Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maurizio","family":"Schiavon","sequence":"additional","affiliation":[{"name":"Physical Activity and Sports Medicine Unit AULSS 6 Euganea Padova Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martina","family":"Perazzolo Marra","sequence":"additional","affiliation":[{"name":"Department of Cardiac, Thoracic and Vascular Sciences University of Padova Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Domenico","family":"Corrado","sequence":"additional","affiliation":[{"name":"Department of Cardiac, Thoracic and Vascular Sciences University of Padova Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2017.03.034"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehp473"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2017.01.015"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2004.05.065"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(02)01977-0"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.47.3.213"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.eurheartj.a061546"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.82.1.19"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(83)90428-9"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(85)90075-4"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1159\/000176327"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/sms.12679"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(94)90841-9"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccep.2016.04.001"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2014.09.009"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.hjr.0000239465.26132.29"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000245"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1093\/ehjci\/jev014"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1186\/1532-429X-15-35"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.116.004229"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.2459\/JCM.0b013e32834102ea"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2008.02.081"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2003.014969"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2008.09.019"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1111\/jce.13309"}],"container-title":["Journal of the American Heart Association"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/JAHA.118.009171","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T07:28:06Z","timestamp":1715585286000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/JAHA.118.009171"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,6,19]]},"references-count":25,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2018,6,19]]}},"alternative-id":["10.1161\/JAHA.118.009171"],"URL":"https:\/\/doi.org\/10.1161\/jaha.118.009171","relation":{},"ISSN":["2047-9980"],"issn-type":[{"value":"2047-9980","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,6,19]]},"assertion":[{"value":"2018-03-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-05-03","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-06-17","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e009171"}}