{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T11:22:32Z","timestamp":1778239352426,"version":"3.51.4"},"reference-count":23,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"14","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2018,7,17]]},"abstract":"<jats:sec xml:lang=\"en\">\n            <jats:title>Background<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              Slow conduction zone in a verapamil\u2010sensitive reentrant atrial tachycardia originating from atrioventricular annulus is composed of calcium channel\u2013dependent tissue. We examined whether there was a slow potential (\n              <jats:styled-content style=\"fixed-case\">SP<\/jats:styled-content>\n              ) at the entrance of the slow conduction zone.\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Methods and Results<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              We first identified the pacing site from where manifest entrainment and orthodromic capture of the earliest atrial activation site were demonstrated in 40 atrioventricular annulus patients with atrioventricular annulus. Radiofrequency energy was then delivered 2\u00a0cm proximal to the earliest atrial activation site in the direction of entrainment pacing site and gradually advanced toward the earliest atrial activation site until atrial tachycardia termination to localize the entrance of the slow conduction zone. Electrogram characteristics were analyzed at successful and unsuccessful ablation sites. During sinus rhythm,\n              <jats:styled-content style=\"fixed-case\">SP<\/jats:styled-content>\n              was observed at all 40 successful sites, but was observed at only 12 unsuccessful sites (\n              <jats:italic>P<\/jats:italic>\n              &lt;0.0001). During sinus rhythm, there was no significant difference in electrogram amplitude nor width of atrial electrogram between successful and unsuccessful sites (0.407\u00b10.281 versus 0.487\u00b10.447\u00a0mV [\n              <jats:italic>P<\/jats:italic>\n              =0.1989] and 37.0\u00b19.2 versus 38.9\u00b18.0\u00a0ms [\n              <jats:italic>P<\/jats:italic>\n              =0.1773]); however,\n              <jats:styled-content style=\"fixed-case\">SP<\/jats:styled-content>\n              amplitude and width at successful sites were significantly greater than those at unsuccessful sites (0.110\u00b10.049 versus 0.025\u00b10.046\u00a0mV [\n              <jats:italic>P<\/jats:italic>\n              &lt;0.0001] and 38.8\u00b113.4 versus 8.1\u00b113.2\u00a0ms [\n              <jats:italic>P<\/jats:italic>\n              &lt;0.0001]). During atrial tachycardia,\n              <jats:styled-content style=\"fixed-case\">SP<\/jats:styled-content>\n              amplitude was significantly attenuated (0.088\u00b10.042 versus 0.110\u00b10.049\u00a0mV,\n              <jats:italic>P<\/jats:italic>\n              &lt;0.001) and\n              <jats:styled-content style=\"fixed-case\">SP<\/jats:styled-content>\n              width was significantly prolonged (47.8\u00b114.1 versus 38.8\u00b113.4\u00a0ms,\n              <jats:italic>P<\/jats:italic>\n              &lt;0.0001) at successful sites.\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              <jats:styled-content style=\"fixed-case\">SP<\/jats:styled-content>\n              was observed during sinus rhythm at the entrance of the slow conduction zone; however,\n              <jats:styled-content style=\"fixed-case\">SP<\/jats:styled-content>\n              amplitude was attenuated and\n              <jats:styled-content style=\"fixed-case\">SP<\/jats:styled-content>\n              width was prolonged during atrial tachycardia, suggesting that\n              <jats:styled-content style=\"fixed-case\">SP<\/jats:styled-content>\n              reflects the characteristics of calcium channel\u2013dependent tissue involved in atrioventricular annulus reentry circuit.\n            <\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/jaha.118.009223","type":"journal-article","created":{"date-parts":[[2018,7,6]],"date-time":"2018-07-06T09:21:29Z","timestamp":1530868889000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":9,"title":["Slow Potential at the Entrance of the Slow Conduction Zone in the Reentry Circuit of a Verapamil\u2010Sensitive Atrial Tachycardia Originating From the Atrioventricular Annulus"],"prefix":"10.1161","volume":"7","author":[{"given":"Hiroshige","family":"Yamabe","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Medicine Graduate School of Medical Sciences Kumamoto University Kumamoto City Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hisanori","family":"Kanazawa","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Graduate School of Medical Sciences Kumamoto University Kumamoto City Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miwa","family":"Ito","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Graduate School of Medical Sciences Kumamoto University Kumamoto City Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shozo","family":"Kaneko","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Graduate School of Medical Sciences Kumamoto University Kumamoto City 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Eur J Cardiol. 1974;2:219\u2013230.","journal-title":"Eur J Cardiol"},{"key":"e_1_3_1_21_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.89.5.2351"},{"key":"e_1_3_1_22_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.94.3.571"},{"key":"e_1_3_1_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2009.01.021"},{"key":"e_1_3_1_24_2","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euw324"}],"container-title":["Journal of the American Heart Association"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/JAHA.118.009223","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T11:06:44Z","timestamp":1715598404000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/JAHA.118.009223"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7,17]]},"references-count":23,"journal-issue":{"issue":"14","published-print":{"date-parts":[[2018,7,17]]}},"alternative-id":["10.1161\/JAHA.118.009223"],"URL":"https:\/\/doi.org\/10.1161\/jaha.118.009223","relation":{},"ISSN":["2047-9980"],"issn-type":[{"value":"2047-9980","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,7,17]]},"assertion":[{"value":"2018-03-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-05-30","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-07-06","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e009223"}}