{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T07:47:23Z","timestamp":1767858443226,"version":"3.49.0"},"reference-count":30,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"19","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2018,10,2]]},"abstract":"\n Background<\/jats:title>\n \n The study sought to assess the prognostic impact of acute myocardial infarction (\n AMI<\/jats:styled-content>\n ) with and without\n ST<\/jats:styled-content>\n \u2010segment\u2013elevation myocardial infarction (\n STEMI<\/jats:styled-content>\n and\n NSTEMI<\/jats:styled-content>\n ) in patients with ventricular tachyarrhythmias and sudden cardiac arrest (\n SCA<\/jats:styled-content>\n ) on admission.\n <\/jats:p>\n <\/jats:sec>\n \n Methods and Results<\/jats:title>\n \n A large retrospective registry was used including all consecutive patients presenting with ventricular tachycardia (\n VT<\/jats:styled-content>\n ), fibrillation (\n VF<\/jats:styled-content>\n ), and sudden cardiac arrest (\n SCA<\/jats:styled-content>\n ) on admission from 2002 to 2016.\n AMI<\/jats:styled-content>\n versus non\u2010\n AMI<\/jats:styled-content>\n and\n STEMI<\/jats:styled-content>\n versus\n NSTEMI<\/jats:styled-content>\n were compared applying multivariable Cox regression models and propensity\u2010score matching for evaluation of the primary prognostic end point defined as long\u2010term all\u2010cause mortality at 2.5\u00a0years. Secondary end points were 30\u00a0days all\u2010cause mortality, cardiac death at 24\u00a0hours, in hospital death, and recurrent percutaneous coronary intervention (re\u2010\n PCI<\/jats:styled-content>\n ) at 2.5\u00a0years. In 2813 unmatched high\u2010risk patients with ventricular tachyarrhythmias and\n SCA<\/jats:styled-content>\n ,\n AMI<\/jats:styled-content>\n was present in 29% (10%\n STEMI<\/jats:styled-content>\n , 19%\n NSTEMI<\/jats:styled-content>\n ) with higher rates of\n VF<\/jats:styled-content>\n (54% versus 31%) and\n SCA<\/jats:styled-content>\n (35% versus 26%), whereas\n VT<\/jats:styled-content>\n rates were higher in non\u2010\n AMI<\/jats:styled-content>\n (56% versus 30%) (\n P<\/jats:italic>\n \u00a0<\u00a00.05).\n AMI<\/jats:styled-content>\n \u2010related\n VT<\/jats:styled-content>\n \u226548\u00a0hours was associated with higher mortality (log rank\n P<\/jats:italic>\n \u00a0=\u00a00.001). Multivariable Cox regression models revealed non\u2010\n AMI<\/jats:styled-content>\n (hazard ratio\u00a0=\u00a01.458;\n P<\/jats:italic>\n \u00a0=\u00a00.001) and\n NSTEMI<\/jats:styled-content>\n (hazard ratio\u00a0=\u00a01.460;\n P<\/jats:italic>\n \u00a0=\u00a00.036) associated with increasing long\u2010term all\u2010cause mortality at 2.5\u00a0years, which was also proven after propensity\u2010score matching (non\u2010\n AMI<\/jats:styled-content>\n versus\n AMI<\/jats:styled-content>\n : 55% versus 43%, log rank\n P<\/jats:italic>\n \u00a0=\u00a00.001, hazard ratio\u00a0=\u00a01.349;\n NSTEMI<\/jats:styled-content>\n versus\n STEMI<\/jats:styled-content>\n : 45% versus 34%, log rank\n P<\/jats:italic>\n \u00a0=\u00a00.047, hazard ratio\u00a0=\u00a01.372). Secondary end points including 30\u00a0days and in\u2010hospital mortality, as well as re\u2010\n PCI<\/jats:styled-content>\n were higher in non\u2010\n AMI<\/jats:styled-content>\n patients.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n In high\u2010risk patients presenting with ventricular tachyarrhythmias and\n SCA<\/jats:styled-content>\n , non\u2010\n AMI<\/jats:styled-content>\n revealed higher mortality than\n AMI<\/jats:styled-content>\n , respectively\n NSTEMI<\/jats:styled-content>\n than\n STEMI<\/jats:styled-content>\n , alongside\n AMI<\/jats:styled-content>\n \u2010related VT \u226548\u00a0hours.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1161\/jaha.118.010004","type":"journal-article","created":{"date-parts":[[2018,9,25]],"date-time":"2018-09-25T09:00:21Z","timestamp":1537866021000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":29,"title":["Prognostic Impact of Acute Myocardial Infarction in Patients Presenting With Ventricular Tachyarrhythmias and Aborted Cardiac Arrest"],"prefix":"10.1161","volume":"7","author":[{"given":"Michael","family":"Behnes","sequence":"first","affiliation":[{"name":"First Department of Medicine Faculty of Medicine Mannheim University Medical Centre Mannheim (UMM) University of Heidelberg European Center for AngioScience (ECAS) Mannheim Germany"},{"name":"DZHK (German Center for Cardiovascular Research) partner site Heidelberg\/Mannheim Mannheim Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kambis","family":"Mashayekhi","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Angiology II University Heart Center Freiburg Bad Krozingen Bad Krozingen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christel","family":"Wei\u00df","sequence":"additional","affiliation":[{"name":"Institute of Biomathematics and Medical Statistics Faculty of Medicine Mannheim University Medical Center Mannheim (UMM) Heidelberg University Mannheim Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christoph","family":"Nienaber","sequence":"additional","affiliation":[{"name":"Royal Brompton and Harefield Hospitals NHS London United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Siegfried","family":"Lang","sequence":"additional","affiliation":[{"name":"First Department of Medicine Faculty of Medicine Mannheim University Medical Centre Mannheim (UMM) University of Heidelberg European Center for AngioScience (ECAS) Mannheim Germany"},{"name":"DZHK (German Center for Cardiovascular Research) partner site Heidelberg\/Mannheim Mannheim Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linda","family":"Reiser","sequence":"additional","affiliation":[{"name":"First Department of Medicine Faculty of Medicine Mannheim University Medical Centre Mannheim (UMM) University of Heidelberg European Center for AngioScience (ECAS) 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