{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T16:07:18Z","timestamp":1793117238553,"version":"4.5.0"},"reference-count":32,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"11","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2019,6,4]]},"abstract":"<jats:sec xml:lang=\"en\">\n            <jats:title>Background<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              Healthcare resource utilization is substantial for single\u2010ventricle cardiac defects (\n              <jats:styled-content style=\"fixed-case\">SVCD<\/jats:styled-content>\n              ), with effort commencing at time of fetal diagnosis through staged surgical palliation. We sought to characterize and identify variables that influence resource utilization for\n              <jats:styled-content style=\"fixed-case\">SVCD<\/jats:styled-content>\n              from fetal diagnosis through death, completed staged palliation, or cardiac transplant.\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Methods and Results<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              Patients with a prenatal diagnosis of\n              <jats:styled-content style=\"fixed-case\">SVCD<\/jats:styled-content>\n              at our institution from 2004 to 2011 were screened. Patients delivered with intent to treat who received cardiac care exclusively at our institution were included. Primary end points included the total days hospitalized and the numbers of echocardiograms and cardiac catheterizations. Subanalysis was performed on survivors of completed staged palliation on the basis of Norwood operation, dominant ventricular morphology, and additional risk factors. Of 202 patients born with intent to treat, 136 patients survived to 6\u00a0months after completed staged palliation. The median number of days hospitalized per patient\u2010year was 25.1\u00a0days, and the median numbers of echocardiograms and catheterizations per patient\u2010year were 7.2 and 0.7, respectively. Mortality is associated with increased resource utilization. Survivors had a cumulative length of stay of 57\u00a0days and underwent a median of 21 echocardiograms and 2 catheterizations through staged palliation. Right\u2010ventricle\u2013dominant lesions requiring Norwood operation are associated with increased resource utilization among survivors of staged palliation.\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              For fetuses with\n              <jats:styled-content style=\"fixed-case\">SVCD<\/jats:styled-content>\n              , those with dominant right\u2010ventricular morphology requiring Norwood operation demand increased resource utilization regardless of mortality. Our findings provide insight into care for\n              <jats:styled-content style=\"fixed-case\">SVCD<\/jats:styled-content>\n              , facilitate precise prenatal counseling, and provide information about the resources utilized to successfully manage\n              <jats:styled-content style=\"fixed-case\">SVCD<\/jats:styled-content>\n              .\n            <\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/jaha.118.011284","type":"journal-article","created":{"date-parts":[[2019,5,29]],"date-time":"2019-05-29T09:10:07Z","timestamp":1559121007000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":12,"title":["Resource Utilization for Prenatally Diagnosed Single\u2010Ventricle Cardiac Defects: A Philadelphia Fetus\u2010to\u2010Fontan Cohort Study"],"prefix":"10.1161","volume":"8","author":[{"given":"Benjamin","family":"Zielonka","sequence":"first","affiliation":[{"name":"Divisions of Cardiology and Cardiothoracic Surgery The Children's Hospital of Philadelphia and the Departments of Pediatrics and Surgery Perelman School of Medicine at the University of Pennsylvania Philadelphia PA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian S.","family":"Snarr","sequence":"additional","affiliation":[{"name":"Divisions of Cardiology and Cardiothoracic Surgery The Children's Hospital of Philadelphia and the Departments of Pediatrics and Surgery Perelman School of Medicine at the University of Pennsylvania Philadelphia PA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael Y.","family":"Liu","sequence":"additional","affiliation":[{"name":"Divisions of Cardiology and Cardiothoracic Surgery The Children's Hospital of Philadelphia and the Departments of Pediatrics and Surgery Perelman School of Medicine at the University of Pennsylvania Philadelphia PA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuemei","family":"Zhang","sequence":"additional","affiliation":[{"name":"Divisions of Cardiology and Cardiothoracic Surgery The Children's Hospital of Philadelphia and the Departments of Pediatrics and Surgery Perelman School of Medicine at the University of Pennsylvania Philadelphia PA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher E.","family":"Mascio","sequence":"additional","affiliation":[{"name":"Divisions of Cardiology and Cardiothoracic Surgery The Children's Hospital of Philadelphia and the Departments of Pediatrics and Surgery Perelman School of Medicine at the University of Pennsylvania Philadelphia PA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie","family":"Fuller","sequence":"additional","affiliation":[{"name":"Divisions of Cardiology and Cardiothoracic Surgery The Children's Hospital of Philadelphia and the Departments of Pediatrics and Surgery Perelman School of Medicine at the University of Pennsylvania Philadelphia PA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. William","family":"Gaynor","sequence":"additional","affiliation":[{"name":"Divisions of Cardiology and Cardiothoracic Surgery The Children's Hospital of Philadelphia and the Departments of Pediatrics and Surgery Perelman School of Medicine at the University of Pennsylvania Philadelphia PA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas L.","family":"Spray","sequence":"additional","affiliation":[{"name":"Divisions of Cardiology and Cardiothoracic Surgery The Children's Hospital of Philadelphia and the Departments of Pediatrics and Surgery Perelman School of Medicine at the University of Pennsylvania Philadelphia PA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jack","family":"Rychik","sequence":"additional","affiliation":[{"name":"Divisions of Cardiology and Cardiothoracic Surgery The Children's Hospital of Philadelphia and the Departments of Pediatrics and Surgery Perelman School of Medicine at the University of Pennsylvania Philadelphia PA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.0000032878.55215.bd"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2008.01.048"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2003.09.027"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-8703(96)90093-9"},{"key":"e_1_3_2_6_2","first-page":"25","article-title":"Hospital stays, hospital charges, and in\u2010hospital deaths among infants with selected birth defects\u2014United States, 2003","volume":"56","author":"Centers for Disease Control and Prevention (CDC)","year":"2007","unstructured":"Centers for Disease Control and Prevention (CDC) . 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