{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T10:55:04Z","timestamp":1792148104189,"version":"4.4.0"},"reference-count":36,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"8","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2019,4,16]]},"abstract":"\n Background<\/jats:title>\n \n Population\u2010based data about the incidence and mortality of patients with aortic dissections (\n ADs<\/jats:styled-content>\n ) are sparse. Therefore, the hospital incidence and in\u2010hospital mortality of patients undergoing open or endovascular surgery for type A\n ADs<\/jats:styled-content>\n (\n TAADs<\/jats:styled-content>\n ) and type\u00a0B\n ADs<\/jats:styled-content>\n (\n TBADs<\/jats:styled-content>\n ) in Germany were analyzed on a nationwide basis between 2006 and 2014.\n <\/jats:p>\n <\/jats:sec>\n \n Methods and Results<\/jats:title>\n \n A secondary data analysis of the nationwide diagnosis\u2010related group statistics, compiled by the German Federal Statistical Office, was performed for patients who were surgically\/interventionally treated for\n AD<\/jats:styled-content>\n (\n International Classification of Diseases, Tenth Revision, German Modification<\/jats:italic>\n [\n \n ICD<\/jats:styled-content>\n \u201010\u2010\n <\/jats:italic>\n \n GM<\/jats:italic>\n ]\n <\/jats:styled-content>\n codes I71.00\u2010I71.07; n=20\u00a0533). By using specific procedure codes, a distinction between\n TAAD<\/jats:styled-content>\n (n=14\u00a0911\/72.6%) and\n TBAD<\/jats:styled-content>\n (n=5622\/27.4%) could be made. The standardized hospital incidence of surgically\/interventionally treated\n AD<\/jats:styled-content>\n was 2.7\/100\u00a0000 per year, comprising 2.0\/100\u00a0000 per year for\n TAAD<\/jats:styled-content>\n and 0.7\/100\u00a0000 per year for\n TBAD<\/jats:styled-content>\n . The in\u2010hospital mortality of\n TAAD<\/jats:styled-content>\n was 19.5%; and of\n TBAD,<\/jats:styled-content>\n 9.3%. Both the incidence and in\u2010hospital mortality increased over the 9\u2010year period. The share of endovascularly treated\n TBAD<\/jats:styled-content>\n increased steadily during the same time interval. A multilevel multivariable analysis revealed that, for\n TAAD<\/jats:styled-content>\n , age and comorbidity were significantly associated with a higher mortality risk.\n <\/jats:p>\n \n The latter was also true for\n TBAD<\/jats:styled-content>\n . Sex was not significantly associated with mortality. A significant association between higher annual center volume and mortality was found for\n TAAD<\/jats:styled-content>\n , but not for\n TBAD<\/jats:styled-content>\n .\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n This is the first report on hospital incidence and mortality for surgically\/interventionally treated\n AD<\/jats:styled-content>\n on a nationwide basis. Overall, in Germany, hospital incidence and mortality of\n TAAD<\/jats:styled-content>\n and\n TBAD<\/jats:styled-content>\n increased over time. In addition,\n TAAD<\/jats:styled-content>\n is performed more safely in high\u2010volume centers.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1161\/jaha.118.011402","type":"journal-article","created":{"date-parts":[[2019,4,12]],"date-time":"2019-04-12T05:04:51Z","timestamp":1555045491000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":68,"title":["Hospital Incidence and In\u2010Hospital Mortality of Surgically and Interventionally Treated Aortic Dissections: Secondary Data Analysis of the Nationwide German Diagnosis\u2010Related Group Statistics From 2006 to 2014"],"prefix":"10.1161","volume":"8","author":[{"given":"Benedikt","family":"Reutersberg","sequence":"first","affiliation":[{"name":"Department of Vascular and Endovascular Surgery Munich Aortic Centre Klinikum rechts der Isar Technical University of Munich Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Salvermoser","sequence":"additional","affiliation":[{"name":"Department of Vascular and Endovascular Surgery Munich Aortic Centre Klinikum rechts der Isar Technical University of Munich Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Trenner","sequence":"additional","affiliation":[{"name":"Department of Vascular and Endovascular Surgery Munich Aortic Centre Klinikum rechts der Isar Technical University of Munich Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Geisb\u00fcsch","sequence":"additional","affiliation":[{"name":"Department of Vascular and Endovascular Surgery Munich Aortic Centre Klinikum rechts der Isar Technical University of Munich Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Zimmermann","sequence":"additional","affiliation":[{"name":"Department of Vascular and Endovascular Surgery Munich Aortic Centre Klinikum rechts der Isar Technical University of Munich Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans\u2010Henning","family":"Eckstein","sequence":"additional","affiliation":[{"name":"Department of Vascular and Endovascular Surgery Munich Aortic Centre Klinikum rechts der Isar Technical University of Munich Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Kuehnl","sequence":"additional","affiliation":[{"name":"Department of Vascular and Endovascular Surgery Munich Aortic Centre Klinikum rechts der Isar Technical University of Munich Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(10)65594-4"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehr186"},{"key":"e_1_3_2_4_2","first-page":"2873","article-title":"ESC guidelines on the diagnosis and treatment of aortic diseases: document covering acute and chronic aortic diseases of the thoracic and abdominal aorta of the adult.","volume":"2014","author":"Erbel R","year":"2014","unstructured":"Erbel R, Aboyans V, Boileau C, Bossone E, Bartolomeo RD, Eggebrecht H, Evangelista A, Falk V, Frank H, Gaemperli O, Grabenw\u00f6ger M, Haverich A, Iung B, Manolis AJ, Meijboom F, Nienaber CA, Roffi M, Rousseau H, Sechtem U, Sirnes PA, von Allmen RS, Vrints CJM, Zamorano JL, Achenbach S, Baumgartner H, Bax JJ, Bueno H, Dean V, Deaton C, Erol \u00c7, Fagard R, Ferrari R, Hasdai D, Hoes A, Kirchhof P, Knuuti J, Kolh P, Lancellotti P, Linhart A, Nihoyannopoulos P, Piepoli MF, Ponikowski P, Sirnes PA, Tamargo JL, Tendera M, Torbicki A, Wijns W, Windecker S, Nihoyannopoulos P, Tendera M, Czerny M, Deanfield J, Mario CD, Pepi M, Taboada MJS, van Sambeek MR, Vlachopoulos C, Zamorano JL, Grimm M, Musayev O, Pasquet A, Ku\u0161ljugi\u0107 Z, Cikes M, Georghiou GP, Stasek J, Molgaard H, K\u00f5vask S, Kyt\u00f6 V, Jondeau G, Bakhutashvili Z, von Kodolitsch Y, Tsioufis C, Temesv\u00e1ri A, Rubinshtein R, Antonini\u2010Canterin F, Lunegova O, Stradins P, Chammas E, Jonkaitiene R, Cassar A, Bj\u00f8rnstad K, Widenka K, Sousa Uva M, Lighezan D, Perunicic J, Madaric J, Vilacosta I, B\u00e4ck M, Mahdhaoui A, Demirbag R, Kravchenko I; Task Force for the Diagnosis and Treatment of Aortic Diseases of the European Society of Cardiology (ESC). 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