{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T14:37:08Z","timestamp":1780497428790,"version":"3.54.1"},"reference-count":39,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2019,2,5]]},"abstract":"<jats:sec xml:lang=\"en\">\n            <jats:title>Background<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              Cardioprotective medication adherence can mitigate the risk of recurrent cardiovascular events and mortality after acute myocardial infarction (\n              <jats:styled-content style=\"fixed-case\">AMI<\/jats:styled-content>\n              ). We examined the associations of diabetes mellitus status and glycemic control with cardioprotective medication adherence after\n              <jats:styled-content style=\"fixed-case\">AMI<\/jats:styled-content>\n              .\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Methods and Results<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              We performed a retrospective observational cohort study of 14\u00a0517\n              <jats:styled-content style=\"fixed-case\">US<\/jats:styled-content>\n              veterans who were hospitalized for their first\n              <jats:styled-content style=\"fixed-case\">AMI<\/jats:styled-content>\n              between 2011 and 2014 and prescribed a beta\u2010blocker, 3\u2010hydroxy\u20103\u2010methyl\u2010glutaryl\u2010CoA\u2010reductase inhibitor, and angiotensin\u2010converting enzyme inhibitor or angiotensin receptor blocker. The primary exposure was a diagnosis of type 2 diabetes mellitus; in diabetes mellitus patients, hemoglobin A1c (HbA1c) was a secondary exposure. The primary outcome was 1\u2010year adherence to all 3 medication classes, defined as proportion of days covered \u22650.8, assessed using adjusted risk differences and multivariable Poisson regression. Of 14\u00a0517 patients (mean age, 66.3\u00a0years; 98% male), 52% had diabetes mellitus; 9%, 31%, 24%, 15%, and 21% had HbA1c &lt;6%, 6% to 6.9%, 7% to 7.9%, 8% to 8.9%, and \u22659%, respectively. Diabetes mellitus patients were more likely to be adherent to all 3 drug classes than those without diabetes mellitus (adjusted difference in adherence, 2.1% [0.5, 3.7]). Relative to those with HbA1c 6% to 6.9%, medication adherence declined with increasing HbA1c (risk ratio of achieving proportion of days covered \u22650.8, 0.99 [0.94, 1.04], 0.93 [0.87, 0.99], 0.82 [0.77, 0.88] for HbA1c 7\u20137.9%, 8\u20138.9%, and \u22659%, respectively).\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              Although diabetes mellitus status had a minor positive impact on cardioprotective medication adherence after\n              <jats:styled-content style=\"fixed-case\">AMI<\/jats:styled-content>\n              , glycemic control at the time of\n              <jats:styled-content style=\"fixed-case\">AMI<\/jats:styled-content>\n              may help identify diabetes mellitus patients at risk of medication nonadherence who may benefit from adherence interventions after\n              <jats:styled-content style=\"fixed-case\">AMI<\/jats:styled-content>\n              .\n            <\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/jaha.118.011448","type":"journal-article","created":{"date-parts":[[2019,2,2]],"date-time":"2019-02-02T10:00:22Z","timestamp":1549101622000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":8,"title":["Association of Diabetes Mellitus Status and Glycemic Control With Secondary Prevention Medication Adherence After Acute Myocardial Infarction"],"prefix":"10.1161","volume":"8","author":[{"given":"Kylie E.","family":"Adamek","sequence":"first","affiliation":[{"name":"Department of Medicine University of Colorado School of Medicine Aurora CO"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deepa","family":"Ramadurai","sequence":"additional","affiliation":[{"name":"Department of Medicine University of Colorado School of Medicine Aurora CO"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elise","family":"Gunzburger","sequence":"additional","affiliation":[{"name":"Veterans Affairs Eastern Colorado Healthcare System Denver CO"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary E.","family":"Plomondon","sequence":"additional","affiliation":[{"name":"Veterans Affairs Eastern Colorado Healthcare System Denver CO"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P. 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