{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T23:41:23Z","timestamp":1787614883946,"version":"build-2736575974"},"reference-count":30,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"9","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2019,5,7]]},"abstract":"<jats:sec xml:lang=\"en\">\n            <jats:title>Background<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              The contemporary incidence of and reasons for early readmission after infective endocarditis (\n              <jats:styled-content style=\"fixed-case\">IE<\/jats:styled-content>\n              ) are not well known. Therefore, we analyzed 30\u2010day readmission demographics after\n              <jats:styled-content style=\"fixed-case\">IE<\/jats:styled-content>\n              from the US Nationwide Readmission Database.\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Methods and Results<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              We examined the 2010 to 2014 Nationwide Readmission Database to identify index admissions for a primary diagnosis of\n              <jats:styled-content style=\"fixed-case\">IE<\/jats:styled-content>\n              with survival at discharge. Incidence, reasons, and independent predictors of 30\u2010day unplanned readmissions were analyzed. In total, 11 217 patients (24.8%) were nonelectively readmitted within 30\u00a0days among the 45 214 index admissions discharged after\n              <jats:styled-content style=\"fixed-case\">IE<\/jats:styled-content>\n              . The most common causes of readmission were\n              <jats:styled-content style=\"fixed-case\">IE<\/jats:styled-content>\n              (20.5%), sepsis (8.7%), complications of device\/graft (8.1%), and congestive heart failure (7.6%). In\u2010hospital mortality and the valvular surgery rates during the readmissions were 8.1% and 9.1%, respectively. Discharge to home or self\u2010care, undergoing valvular surgery, aged \u226560\u00a0years, and having private insurance were independently associated with lower rates of 30\u2010day readmission. Length of stay of \u226510\u00a0days, congestive heart failure, diabetes mellitus, renal failure, chronic pulmonary disease, peripheral artery disease, and depression were associated with higher risk. The total hospital costs of readmission were $48.7\u00a0million per year (median, $11 267; interquartile range, $6021\u2013$25 073), which accounted for 38.6% of the total episodes of care (index+readmission).\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              Almost 1 in 4 patients was readmitted within 30\u00a0days of admission for\n              <jats:styled-content style=\"fixed-case\">IE<\/jats:styled-content>\n              . The most common reasons were\n              <jats:styled-content style=\"fixed-case\">IE<\/jats:styled-content>\n              , other infectious causes, and cardiac causes. A multidisciplinary approach to determine the surgical indications and close monitoring are necessary to improve outcomes and reduce complications in in\u2010hospital and postdischarge settings.\n            <\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/jaha.118.011598","type":"journal-article","created":{"date-parts":[[2019,4,25]],"date-time":"2019-04-25T09:23:46Z","timestamp":1556184226000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":32,"title":["Thirty\u2010Day Readmission After Infective Endocarditis: Analysis From a Nationwide Readmission Database"],"prefix":"10.1161","volume":"8","author":[{"given":"Yusuke","family":"Morita","sequence":"first","affiliation":[{"name":"Cardiovascular Center Tazuke Kofukai Foundation Medical Research Institute Kitano Hospital Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tetsuya","family":"Haruna","sequence":"additional","affiliation":[{"name":"Cardiovascular Center Tazuke Kofukai Foundation Medical Research Institute Kitano Hospital Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshisumi","family":"Haruna","sequence":"additional","affiliation":[{"name":"Cardiovascular Center Tazuke Kofukai Foundation Medical Research Institute Kitano Hospital Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eisaku","family":"Nakane","sequence":"additional","affiliation":[{"name":"Cardiovascular Center Tazuke Kofukai Foundation Medical Research Institute Kitano Hospital Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuhei","family":"Yamaji","sequence":"additional","affiliation":[{"name":"Cardiovascular Center Tazuke Kofukai Foundation Medical Research Institute Kitano Hospital Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideyuki","family":"Hayashi","sequence":"additional","affiliation":[{"name":"Cardiovascular Center Tazuke Kofukai Foundation Medical Research Institute Kitano Hospital Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michiya","family":"Hanyu","sequence":"additional","affiliation":[{"name":"Cardiovascular Center Tazuke Kofukai Foundation Medical Research Institute Kitano Hospital Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moriaki","family":"Inoko","sequence":"additional","affiliation":[{"name":"Cardiovascular Center Tazuke Kofukai Foundation Medical Research Institute Kitano Hospital Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehq110"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2017.4287"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2334-8-49"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(94)90143-0"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra010082"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-114-8-635"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.109.864488"},{"key":"e_1_3_1_9_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1112843"},{"key":"e_1_3_1_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2017.02.077"},{"key":"e_1_3_1_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2005.01289.x"},{"key":"e_1_3_1_12_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0082665"},{"key":"e_1_3_1_13_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-156-1-201201030-00004"},{"key":"e_1_3_1_14_2","unstructured":"US Agency for Healthcare Research and Quality . 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