{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,25]],"date-time":"2026-04-25T20:18:24Z","timestamp":1777148304045,"version":"3.51.4"},"reference-count":49,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"14","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2019,7,16]]},"abstract":"\n Background<\/jats:title>\n \n Blood pressure (\n BP<\/jats:styled-content>\n ) varies over time within individual patients and across different\n BP<\/jats:styled-content>\n measurement techniques. The effect of different\n BP<\/jats:styled-content>\n targets on concordance between\n BP<\/jats:styled-content>\n measurements is unknown. The goals of this analysis are to evaluate concordance between (1) clinic and ambulatory\n BP<\/jats:styled-content>\n , (2) clinic visit\u2010to\u2010visit variability and ambulatory\n BP<\/jats:styled-content>\n variability, and (3) first and second ambulatory\n BP<\/jats:styled-content>\n and to evaluate whether different clinic targets affect these relationships.\n <\/jats:p>\n <\/jats:sec>\n \n Methods and Results<\/jats:title>\n \n The SPRINT (Systolic Blood Pressure Intervention Trial) ambulatory\n BP<\/jats:styled-content>\n monitoring ancillary study obtained ambulatory\n BP<\/jats:styled-content>\n readings in 897 participants at the 27\u2010month follow\u2010up visit and obtained a second reading in 203 participants 293\u00b184\u00a0days afterward. There was considerable lack of agreement between clinic and daytime ambulatory systolic\n BP<\/jats:styled-content>\n with wide limits of agreement in Bland\u2010Altman plots of \u221221 to 34\u00a0mm\u00a0Hg in the intensive\u2010treatment group and \u221226 to 32\u00a0mm\u00a0Hg in the standard\u2010treatment group. Overall, there was poor agreement between clinic visit\u2010to\u2010visit variability and ambulatory\n BP<\/jats:styled-content>\n variability with correlation coefficients for systolic and diastolic\n BP<\/jats:styled-content>\n all <0.16. We observed a high correlation between first and second ambulatory\n BP<\/jats:styled-content>\n ; however, the limits of agreement were wide in both the intensive group (\u221227 to 21\u00a0mm\u00a0Hg) and the standard group (\u221223 to 20\u00a0mm\u00a0Hg).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n We found low concordance in\n BP<\/jats:styled-content>\n and\n BP<\/jats:styled-content>\n variability between clinic and ambulatory\n BP<\/jats:styled-content>\n and second ambulatory\n BP<\/jats:styled-content>\n . Results did not differ by treatment arm. These results reinforce the need for multiple\n BP<\/jats:styled-content>\n measurements before clinical decision making.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1161\/jaha.118.011706","type":"journal-article","created":{"date-parts":[[2019,7,16]],"date-time":"2019-07-16T04:00:04Z","timestamp":1563249604000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":19,"title":["Effect of Intensive and Standard Clinic\u2010Based Hypertension Management on the Concordance Between Clinic and Ambulatory Blood Pressure and Blood Pressure Variability in SPRINT"],"prefix":"10.1161","volume":"8","author":[{"given":"Lama","family":"Ghazi","sequence":"first","affiliation":[{"name":"Division of Public Health Department of Epidemiology and Community Health University of Minnesota Minneapolis MN"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicholas M.","family":"Pajewski","sequence":"additional","affiliation":[{"name":"Division of Public Health Sciences Department of Biostatistical Sciences Wake Forest School of Medicine Winston\u2010Salem NC"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dena E.","family":"Rifkin","sequence":"additional","affiliation":[{"name":"Division of Nephrology Veterans Affairs Health System and University of California San Diego CA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffrey T.","family":"Bates","sequence":"additional","affiliation":[{"name":"Michael E. DeBakey Veterans Affairs Medical Center and Baylor College of Medicine Houston TX"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tara I.","family":"Chang","sequence":"additional","affiliation":[{"name":"Division of Nephrology Stanford University School of Medicine Palo Alto CA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William C.","family":"Cushman","sequence":"additional","affiliation":[{"name":"Memphis Veterans Affairs Medical Center Memphis TN"},{"name":"Department of Preventive Medicine University of Tennessee Health Science Center Memphis TN"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen P.","family":"Glasser","sequence":"additional","affiliation":[{"name":"Division of Cardiology Department of Internal Medicine University of Kentucky College of Medicine Lexington KY"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William E.","family":"Haley","sequence":"additional","affiliation":[{"name":"Division of Nephrology and Hypertension Mayo Clinic Jacksonville FL"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karen C.","family":"Johnson","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine University of Tennessee Health Science Center Memphis TN"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William J.","family":"Kostis","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Disease and Hypertension Rutgers Robert Wood Johnson Medical School New Brunswick NJ"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vasilios","family":"Papademetriou","sequence":"additional","affiliation":[{"name":"Department of Veterans Affairs and Georgetown University Washington DC"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahboob","family":"Rahman","sequence":"additional","affiliation":[{"name":"Case Western Reserve University University Hospitals Cleveland Medical Center Louis Stokes Cleveland VA Medical Center Cleveland OH"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Debra L.","family":"Simmons","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine University of Utah Salt Lake City UT"},{"name":"George E. Wahlen Veterans Affairs Medical Center Salt Lake City UT"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Addison","family":"Taylor","sequence":"additional","affiliation":[{"name":"Michael E. DeBakey Veterans Affairs Medical Center and Baylor College of Medicine Houston TX"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul K.","family":"Whelton","sequence":"additional","affiliation":[{"name":"Tulane University School of Public Health and Tropical Medicine New Orleans LA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jackson T.","family":"Wright","sequence":"additional","affiliation":[{"name":"Clinical Hypertension Program Division of Nephrology and Hypertension University Hospitals Cleveland Medical Center Cleveland OH"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Udayan Y.","family":"Bhatt","sequence":"additional","affiliation":[{"name":"Division of Nephrology The Ohio State University, Wexner Medical Center Columbus OH"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul E.","family":"Drawz","sequence":"additional","affiliation":[{"name":"Division of Renal Diseases and Hypertension University of Minnesota Minneapolis MN"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.112.194340"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2281.2001.00332.x"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.0000200695.34024.4c"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.325.7358.254"},{"key":"e_1_3_2_6_2","first-page":"13","article-title":"An epidemiological approach to ambulatory blood pressure monitoring: the Belgian Population Study","volume":"1","author":"Staessen JA","year":"1996","unstructured":"Staessen JA, Bieniaszewski L, O'Brien ET, Imai Y, Fagard R. 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