{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T03:30:50Z","timestamp":1789702250576,"version":"4.0.1"},"reference-count":25,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"13","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2019,7,2]]},"abstract":"<jats:sec xml:lang=\"en\">\n            <jats:title>Background<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              Percutaneous mitral commissurotomy (\n              <jats:styled-content style=\"fixed-case\">PMC<\/jats:styled-content>\n              ) was the first available transcatheter technique for treatment of mitral valve diseases. Experience has led to extending the indications to patients with less favorable characteristics. We aimed to analyze (1) the temporal trends in characteristic and outcomes of patients undergoing\n              <jats:styled-content style=\"fixed-case\">PMC<\/jats:styled-content>\n              in a single center over 30\u00a0years and (2) the predictive factors of poor immediate results of\n              <jats:styled-content style=\"fixed-case\">PMC<\/jats:styled-content>\n              .\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Methods and Results<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              From 1987 to 2016, 1 full year for each decade was analyzed: 1987, 1996, 2006, and 2016. Poor immediate results of\n              <jats:styled-content style=\"fixed-case\">PMC<\/jats:styled-content>\n              were defined as a mitral valve area &lt;1.5\u00a0cm\n              <jats:sup>2<\/jats:sup>\n              or\n              <jats:styled-content style=\"fixed-case\">MR<\/jats:styled-content>\n              (mitral regurgitation) grade &gt;2. Mitral anatomy was assessed using the Cormier classification and the fluoroscopic extent of calcification. Six hundred three patients were included: 111, 202, 205, and 85, respectively. Mean age increased &gt;10\u00a0years over time (\n              <jats:italic>P<\/jats:italic>\n              &lt;0.0001). Mitral anatomy was less favorable over the years: the presence of calcification increased from 25% of patients at the beginning of\n              <jats:styled-content style=\"fixed-case\">PMC<\/jats:styled-content>\n              to &gt;40% during the past decade (\n              <jats:italic>P<\/jats:italic>\n              &lt;0.0001) with a 3\u2010fold increase in severe mitral calcification. Consistently, the proportion of good immediate results decreased over time (\n              <jats:italic>P<\/jats:italic>\n              &lt;0.05) but remained at 76% in 2016. Multivariate analysis showed 3 predictive factors of poor immediate results: smaller baseline mitral valve area (\n              <jats:italic>P<\/jats:italic>\n              &lt;0.0001), pre\u2010\n              <jats:styled-content style=\"fixed-case\">PMC MR<\/jats:styled-content>\n              grade 2 (\n              <jats:italic>P<\/jats:italic>\n              &lt;0.01), and the presence or amount of calcification (\n              <jats:italic>P<\/jats:italic>\n              &lt;0.001).\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              This clinic's patients became significantly older with more frequent and severe calcification in the past decade. Predictive factors of poor immediate results were related to valve anatomy, including calcification. Despite challenges raised by severe calcification,\n              <jats:styled-content style=\"fixed-case\">PMC<\/jats:styled-content>\n              was still successful in &gt;3 out of 4 patients in recent years.\n            <\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/jaha.119.012031","type":"journal-article","created":{"date-parts":[[2019,6,29]],"date-time":"2019-06-29T09:04:05Z","timestamp":1561799045000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":28,"title":["Temporal Trends on Percutaneous Mitral Commissurotomy: 30\u00a0Years of Experience"],"prefix":"10.1161","volume":"8","author":[{"given":"Cyrielle","family":"Desnos","sequence":"first","affiliation":[{"name":"Department of Cardiology Bichat Hospital AP\u2010HP Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernard","family":"Iung","sequence":"additional","affiliation":[{"name":"Department of Cardiology Bichat Hospital AP\u2010HP Paris France"},{"name":"DHU Fire Paris\u2010Diderot University Sorbonne Paris Cit\u00e9 Paris France"},{"name":"INSERM U1148 Bichat Hospital Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominique","family":"Himbert","sequence":"additional","affiliation":[{"name":"Department of Cardiology Bichat Hospital AP\u2010HP Paris France"},{"name":"DHU Fire Paris\u2010Diderot University Sorbonne Paris Cit\u00e9 Paris France"},{"name":"INSERM U1148 Bichat Hospital Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gr\u00e9gory","family":"Ducrocq","sequence":"additional","affiliation":[{"name":"Department of Cardiology Bichat Hospital AP\u2010HP Paris France"},{"name":"DHU Fire Paris\u2010Diderot University Sorbonne Paris Cit\u00e9 Paris France"},{"name":"INSERM U1148 Bichat Hospital Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina","family":"Urena","sequence":"additional","affiliation":[{"name":"Department of Cardiology Bichat Hospital AP\u2010HP Paris France"},{"name":"DHU Fire Paris\u2010Diderot University Sorbonne Paris Cit\u00e9 Paris France"},{"name":"INSERM U1148 Bichat Hospital Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bertrand","family":"Cormier","sequence":"additional","affiliation":[{"name":"Department of Cardiology Bichat Hospital AP\u2010HP Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Brochet","sequence":"additional","affiliation":[{"name":"Department of Cardiology Bichat Hospital AP\u2010HP Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phalla","family":"Ou","sequence":"additional","affiliation":[{"name":"Department of Radiology Bichat Hospital AP\u2010HP Paris France"},{"name":"DHU Fire Paris\u2010Diderot University Sorbonne Paris Cit\u00e9 Paris France"},{"name":"INSERM U1148 Bichat Hospital Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alec","family":"Vahanian","sequence":"additional","affiliation":[{"name":"Department of Cardiology Bichat Hospital AP\u2010HP Paris France"},{"name":"DHU Fire Paris\u2010Diderot University Sorbonne Paris Cit\u00e9 Paris France"},{"name":"INSERM U1148 Bichat Hospital Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire","family":"Bouleti","sequence":"additional","affiliation":[{"name":"Department of Cardiology Bichat Hospital AP\u2010HP Paris France"},{"name":"DHU Fire Paris\u2010Diderot University Sorbonne Paris Cit\u00e9 Paris France"},{"name":"INSERM U1148 Bichat Hospital Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/cir.0000000000000031"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehx391"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.118.007038"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(19)37390-8"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cjca.2014.03.022"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2015.08.872"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.115.020185"},{"key":"e_1_3_1_9_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.111.055905"},{"key":"e_1_3_1_10_2","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl-2013-303944"},{"key":"e_1_3_1_11_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.94.9.2124"},{"key":"e_1_3_1_12_2","first-page":"185","article-title":"Evaluation by two\u2010dimensional and Doppler echocardiography of the results of percutaneous mitral valvuloplasty [Article in French]","volume":"82","author":"Cormier B","year":"1989","unstructured":"Cormier B, Vahanian A, Michel PL, Starkman C, Enriquez L, Kulas A, Vitoux B, Acar J. 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