{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T17:34:30Z","timestamp":1789580070398,"version":"build-2803163510"},"reference-count":30,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"13","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2019,7,2]]},"abstract":"<jats:sec xml:lang=\"en\">\n            <jats:title>Background<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              The effects of severe acute stent malapposition (\n              <jats:styled-content style=\"fixed-case\">ASM<\/jats:styled-content>\n              ) after drug\u2010eluting stent implantation on long\u2010term clinical outcomes are not clearly understood. We evaluated long\u2010term clinical outcomes of severe\n              <jats:styled-content style=\"fixed-case\">ASM<\/jats:styled-content>\n              using optical coherence tomography.\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Methods and Results<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              We pooled patient\u2010 and lesion\u2010level data from 6 randomized studies. Five studies investigated follow\u2010up drug\u2010eluting stent strut coverage and one investigated\n              <jats:styled-content style=\"fixed-case\">ASM<\/jats:styled-content>\n              . In this data set, a total of 436 patients with 444 lesions underwent postintervention optical coherence tomography examination and these data were included in the analysis. Severe\n              <jats:styled-content style=\"fixed-case\">ASM<\/jats:styled-content>\n              was defined as lesions with \u2265400\u00a0\u03bcm of maximum malapposed distance or \u22651\u00a0mm of maximum malapposed length. Composite events (cardiac death, target lesion\u2013related myocardial infarction, target lesion revascularization, and stent thrombosis) were compared between patients with and without severe\n              <jats:styled-content style=\"fixed-case\">ASM<\/jats:styled-content>\n              . The postintervention optical coherence tomography findings indicated that 62 (14.2%) patients had lesions with \u2265400\u00a0\u03bcm of maximum malapposed distance and 186 (42.7%) patients had lesions with \u22651\u00a0mm of maximum malapposed length. The 5\u2010year clinical follow\u2010up was completed in 371 (86.1%) of the eligible 431 patients. The cumulative rate of composite events was similar among the patients in each group during 5\u2010year follow\u2010up: 3.3% in patients with\n              <jats:styled-content style=\"fixed-case\">ASM<\/jats:styled-content>\n              \u2265400\u00a0\u03bcm of maximum malapposed distance versus 3.1% in those with no\n              <jats:styled-content style=\"fixed-case\">ASM<\/jats:styled-content>\n              or\n              <jats:styled-content style=\"fixed-case\">ASM<\/jats:styled-content>\n              &lt;400\u00a0\u03bcm of maximum malapposed distance (\n              <jats:italic>P<\/jats:italic>\n              =0.89), and 1.2% in patients with\n              <jats:styled-content style=\"fixed-case\">ASM<\/jats:styled-content>\n              \u22651\u00a0mm of maximum malapposed length versus 4.6% in those with no\n              <jats:styled-content style=\"fixed-case\">ASM<\/jats:styled-content>\n              or\n              <jats:styled-content style=\"fixed-case\">ASM<\/jats:styled-content>\n              &lt;1\u00a0mm of maximum malapposed length (\n              <jats:italic>P<\/jats:italic>\n              =0.06).\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              During the 5\u2010year follow\u2010up,\n              <jats:styled-content style=\"fixed-case\">ASM<\/jats:styled-content>\n              severity was not associated with long\u2010term clinical outcomes in patients treated with drug\u2010eluting stents.\n            <\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/jaha.119.012800","type":"journal-article","created":{"date-parts":[[2019,6,25]],"date-time":"2019-06-25T12:26:21Z","timestamp":1561465581000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":26,"title":["Severe Acute Stent Malapposition After Drug\u2010Eluting Stent Implantation: Effects on Long\u2010Term Clinical Outcomes"],"prefix":"10.1161","volume":"8","author":[{"given":"Seung\u2010Yul","family":"Lee","sequence":"first","affiliation":[{"name":"Sanbon Hospital\rWonkwang University College of Medicine\rGunpo Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eui","family":"Im","sequence":"additional","affiliation":[{"name":"Yongin Severance Hospital\rYonsei University Health System\rYongin Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung\u2010Jin","family":"Hong","sequence":"additional","affiliation":[{"name":"Severance Cardiovascular Hospital\rYonsei University Health System\rSeoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chul\u2010Min","family":"Ahn","sequence":"additional","affiliation":[{"name":"Severance Cardiovascular Hospital\rYonsei University Health System\rSeoul 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