{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,24]],"date-time":"2026-01-24T19:48:03Z","timestamp":1769284083506,"version":"3.49.0"},"reference-count":30,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2020,3,3]]},"abstract":"\n Background<\/jats:title>\n Optimal blood pressure in elderly patients after acute myocardial infarction is still a matter of debate. In a prospective observational study, we aimed to identify optimal systolic blood pressure during the 48 first hours after admission for acute myocardial infarction and its prognostic value for cardiovascular mortality.<\/jats:p>\n <\/jats:sec>\n \n Methods and Results<\/jats:title>\n \n From the Observatoire des Infarctus de C\u00f4te d'Or survey, all consecutive patients aged >75\u00a0years admitted for an acute myocardial infarction in a coronary care unit from 2012 to 2015 and discharged alive were included (n=814). Exclusion criteria were in\u2010hospital death, cardiogenic shock, and end\u2010stage renal disease. Average\n systolic blood pressure<\/jats:styled-content>\n (\n aSBP<\/jats:styled-content>\n ) values over the first 48\u00a0hours after admission were recorded, and the population was dichotomized into 2 groups: low aSBP group (<125\u00a0mm\u00a0Hg) and control group (\n aSBP<\/jats:styled-content>\n \u2265125\u00a0mm\u00a0Hg). When compared with patients without cardiovascular death at 1\u2010year follow\u2010up, patients who died from a cardiovascular cause had higher rate of cardiovascular risks factors, including age, diabetes mellitus, comorbidities, and cardiovascular history. They had higher rates of low body mass index (<21\u00a0kg\/m\n 2<\/jats:sup>\n ) and more elevated Global Registry of Acute Coronary Events risk score. Patients with\n aSBP<\/jats:styled-content>\n <125\u00a0mm\u00a0Hg had a 2\u2010fold risk of 1\u2010year cardiovascular death (47 [12.0%] versus 28 [6.6%];\n P<\/jats:italic>\n =0.008). By multivariable logistic regression analysis, low\n aSBP<\/jats:styled-content>\n (odds ratio [95%\n CI<\/jats:styled-content>\n ], 1.91 [1.07\u20133.41]) remained a strong and independent predictor of 1\u2010year cardiovascular mortality.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n In our large population\u2010based study in elderly patients with acute myocardial infarction, low\n aSBP<\/jats:styled-content>\n was an independent and powerful predictor of 1\u2010year cardiovascular mortality. Early\n aSBP<\/jats:styled-content>\n measurement could help to improve risk stratification. Moreover, our results may suggest an optimal blood pressure target in elderly patients.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1161\/jaha.119.013030","type":"journal-article","created":{"date-parts":[[2020,2,26]],"date-time":"2020-02-26T10:00:44Z","timestamp":1582711244000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":26,"title":["Low Systolic Blood Pressure and Mortality in Elderly Patients After Acute Myocardial Infarction"],"prefix":"10.1161","volume":"9","author":[{"given":"Basile","family":"Mouhat","sequence":"first","affiliation":[{"name":"Service de Cardiologie CHU Dijon Dijon France"},{"name":"Laboratoire Physiopathologie et Epid\u00e9miologie C\u00e9r\u00e9bro\u2010Cardiovasculaires EA 7460 Universit\u00e9 de Bourgogne Franche\u2010Comt\u00e9 Dijon France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alain","family":"Putot","sequence":"additional","affiliation":[{"name":"M\u00e9decine Interne G\u00e9riatrie P\u00f4le Personnes \u00c2g\u00e9es Centre Hospitalier Universitaire de Dijon Dijon France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olivier","family":"Hanon","sequence":"additional","affiliation":[{"name":"Service de G\u00e9riatrie Assistance Publique \u2013 H\u00f4pitaux de Paris H\u00f4pital Broca Paris France"},{"name":"EA 4468 Universit\u00e9 Paris Descartes Sorbonne Paris Cit\u00e9, Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean Christophe","family":"Eicher","sequence":"additional","affiliation":[{"name":"Service de Cardiologie CHU Dijon Dijon France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fr\u00e9d\u00e9ric","family":"Chagu\u00e9","sequence":"additional","affiliation":[{"name":"Service de Cardiologie CHU Dijon Dijon France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean\u2010Claude","family":"Beer","sequence":"additional","affiliation":[{"name":"Service de Cardiologie CHU Dijon Dijon France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maud","family":"Maza","sequence":"additional","affiliation":[{"name":"Service de Cardiologie CHU Dijon Dijon France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marianne","family":"Zeller","sequence":"additional","affiliation":[{"name":"Laboratoire Physiopathologie et Epid\u00e9miologie C\u00e9r\u00e9bro\u2010Cardiovasculaires EA 7460 Universit\u00e9 de Bourgogne Franche\u2010Comt\u00e9 Dijon France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yves","family":"Cottin","sequence":"additional","affiliation":[{"name":"Service de Cardiologie CHU Dijon Dijon France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Observatoire des Infarctus de C\u00f4te d'Or Survey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/31.4.776"},{"key":"e_1_3_2_3_2","first-page":"764","article-title":"Myocardial infarction in women: trends of hospitalization and mortality rates, France, 2002\u20132013","volume":"43","author":"Gabet A","year":"2016","unstructured":"Gabet A, Danchin N, Oli\u00e9 V. 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