{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T09:12:36Z","timestamp":1775034756214,"version":"3.50.1"},"reference-count":27,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"19","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:sec id=\"jah34441-sec-0001\" xml:lang=\"en\">\n            <jats:title>Background<\/jats:title>\n            <jats:p xml:lang=\"en\">Many patients with severe aortic stenosis are referred late with advanced symptoms or inappropriately denied intervention. The objective was to investigate whether a structured communication to referring physicians (facilitated data relay) might improve the rate and timeliness of intervention.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec id=\"jah34441-sec-0002\" xml:lang=\"en\">\n            <jats:title>Methods and Results<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              A prospective registry of consecutive patients with severe aortic stenosis at 23 centers in 9 European countries with transcatheter as well as surgical aortic valve replacement being available was performed. The study included a 3\u2010month documentation of the status quo (phase A), a 6\u2010month intervention phase (implementing facilitated data relay), and a 3\u2010month documentation of a legacy effect (phase\u2010B). Two thousand one hundred seventy\u2010one patients with severe aortic stenoses were enrolled (phase A: 759; intervention: 905; phase\u2010B: 507). Mean age was 77.9\u00b110.0\u00a0years, and 80% were symptomatic, including 52% with severe symptoms. During phase A, intervention was planned in 464\/696 (67%), 138 (20%) were assigned to watchful waiting, 8 (1%) to balloon aortic valvuloplasty, 60 (9%) were listed as not for active treatment, and in 26 (4%), no decision was made. Three hundred sixty\u2010three of 464 (78%) patients received the planned intervention within 3\u00a0months. Timeliness of the intervention improved as shown by the higher number of aortic valve replacements performed within 3\u00a0months (59% versus 51%,\n              <jats:italic toggle=\"yes\">P<\/jats:italic>\n              =0.002) and a significant decrease in the time to intervention (36\u00b138 versus 30\u00b133\u00a0days,\n              <jats:italic toggle=\"yes\">P<\/jats:italic>\n              =0.002).\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec id=\"jah34441-sec-0003\" xml:lang=\"en\">\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p xml:lang=\"en\">A simple, low\u2010cost, facilitated data relay improves timeliness of treatment for patients diagnosed with severe aortic stenosis, resulting in a shorter time to transcatheter aortic valve replacement. This effect was mainly driven by a significant improvement in timeliness of intervention in transcatheter aortic valve replacement but not surgical aortic valve replacement.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec id=\"jah34441-sec-0004\" xml:lang=\"en\">\n            <jats:title>Clinical Trial Registration<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              <jats:styled-content style=\"fixed-case\" toggle=\"no\">URL<\/jats:styled-content>\n              :\n              <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/www.clinicaltrials.gov\/\">https:\/\/www.clinicaltrials.gov\/<\/jats:ext-link>\n              . Unique identifier:\n              <jats:styled-content style=\"fixed-case\" toggle=\"no\">NCT<\/jats:styled-content>\n              02241447.\n            <\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/jaha.119.013160","type":"journal-article","created":{"date-parts":[[2019,9,24]],"date-time":"2019-09-24T09:12:06Z","timestamp":1569316326000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":12,"title":["Facilitated Data Relay and Effects on Treatment of Severe Aortic Stenosis in Europe"],"prefix":"10.1161","volume":"8","author":[{"given":"Richard P.","family":"Steeds","sequence":"first","affiliation":[{"name":"University of Birmingham","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthias","family":"Lutz","sequence":"additional","affiliation":[{"name":"University of 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