{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T00:47:37Z","timestamp":1786322857945,"version":"build-2736575974"},"reference-count":50,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"17","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2019,9,3]]},"abstract":"\n Background<\/jats:title>\n \n Although it has been reported that renal function can improve after catheter ablation of atrial fibrillation (\n AF<\/jats:styled-content>\n ), long\u2010term changes in renal function and its relationship to rhythm outcomes have not yet been evaluated. We explored the 5\u2010year change in estimated glomerular filtration rate (\n eGFR<\/jats:styled-content>\n ) in\n AF<\/jats:styled-content>\n patients depending on medical therapy and catheter ablation.\n <\/jats:p>\n <\/jats:sec>\n \n Methods and Results<\/jats:title>\n \n Among 1963 patients who underwent\n AF<\/jats:styled-content>\n catheter ablation and 14\u00a0056 with\n AF<\/jats:styled-content>\n under medical therapy in the National Health Insurance Service database, we compared 571 with\n AF<\/jats:styled-content>\n catheter ablation (59\u00b110\u00a0years old, 72.3% male, and 66.5% paroxysmal\n AF<\/jats:styled-content>\n ) and 1713 with medical therapy after 1:3 propensity\u2010score matching. All participants had 5\u00a0years of serial\n eGFR<\/jats:styled-content>\n data (Chronic Kidney Disease\u2010Epidemiology Collaboration [\n CKD<\/jats:styled-content>\n \u2010\n EPI<\/jats:styled-content>\n ] method). Catheter ablation improved\n eGFR<\/jats:styled-content>\n 5\u00a0yrs<\/jats:sub>\n (\n P<\/jats:italic>\n <0.001), but medical therapy did not. In 2284 matched patients, age (adjusted odds ratio [\n OR<\/jats:styled-content>\n ], 0.98 [0.97\u20130.99];\n P<\/jats:italic>\n <0.001) and\n AF<\/jats:styled-content>\n catheter ablation (adjusted\n OR<\/jats:styled-content>\n , 2.02 [1.67\u20132.46];\n P<\/jats:italic>\n <0.001) were independently associated with an improved\n eGFR<\/jats:styled-content>\n 5\u00a0yrs<\/jats:sub>\n . Among 571 patients who underwent\n AF<\/jats:styled-content>\n ablation, freedom from\n AF<\/jats:styled-content>\n \/atrial tachycardia recurrence after the last\n AF<\/jats:styled-content>\n ablation procedure was independently associated with an improved\n eGFR<\/jats:styled-content>\n 5\u00a0yrs<\/jats:sub>\n (adjusted\n OR<\/jats:styled-content>\n , 1.44 [1.01\u20132.04];\n P<\/jats:italic>\n =0.043), especially in patients without diabetes mellitus (adjusted\n OR<\/jats:styled-content>\n , 1.78 [1.21\u20132.63];\n P<\/jats:italic>\n =0.003,\n P<\/jats:italic>\n for interaction=0.012). Although underlying renal dysfunction (<60\u00a0mL\/min\/1.73m\n 2<\/jats:sup>\n ) was associated with atrial structural remodeling (adjusted\n OR<\/jats:styled-content>\n , 1.05 [1.00\u20131.11];\n P<\/jats:italic>\n =0.046), it did not affect the\n AF<\/jats:styled-content>\n ablation rhythm outcome.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n AF<\/jats:styled-content>\n catheter ablation significantly improved renal function over a 5\u2010year follow\u2010up, especially in patients maintaining sinus rhythm without preexisting diabetes mellitus.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1161\/jaha.119.013204","type":"journal-article","created":{"date-parts":[[2019,8,31]],"date-time":"2019-08-31T09:01:08Z","timestamp":1567242068000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":36,"title":["Five\u2010Year Change in the Renal Function After Catheter Ablation of Atrial Fibrillation"],"prefix":"10.1161","volume":"8","author":[{"given":"Je\u2010Wook","family":"Park","sequence":"first","affiliation":[{"name":"Yonsei University Health System Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pil\u2010Sung","family":"Yang","sequence":"additional","affiliation":[{"name":"Division of Cardiology CHA University Seongnam Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Han\u2010Joon","family":"Bae","sequence":"additional","affiliation":[{"name":"Daegu Catholic University Medical Center Daegu Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Song\u2010Yi","family":"Yang","sequence":"additional","affiliation":[{"name":"Yonsei University Health System Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hee Tae","family":"Yu","sequence":"additional","affiliation":[{"name":"Yonsei University Health System Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tae\u2010Hoon","family":"Kim","sequence":"additional","affiliation":[{"name":"Yonsei University Health System Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae\u2010Sun","family":"Uhm","sequence":"additional","affiliation":[{"name":"Yonsei University Health System Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Boyoung","family":"Joung","sequence":"additional","affiliation":[{"name":"Yonsei University Health System Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moon\u2010Hyoung","family":"Lee","sequence":"additional","affiliation":[{"name":"Yonsei University Health System Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui\u2010Nam","family":"Pak","sequence":"additional","affiliation":[{"name":"Yonsei University Health System Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehw210"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.03.034"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa041031"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.792903"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2010.03.027"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.03170509"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2013.05.010"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.118.008928"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.293.21.2634"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1707855"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2019.0693"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2018.01.043"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2011.02035.x"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.119.007197"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.111.047266"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euu346"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1111\/jce.12398"},{"key":"e_1_3_2_19_2","first-page":"961","article-title":"Pulmonary vein reconnection predicts good clinical outcome after second catheter ablation for atrial fibrillation","volume":"19","author":"Kim TH","year":"2017","unstructured":"Kim TH, Park J, Uhm JS, Joung B, Lee MH, Pak HN. 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