{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T15:28:31Z","timestamp":1787239711176,"version":"build-2736575974"},"reference-count":31,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"19","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2019,10]]},"abstract":"\n Background<\/jats:title>\n While venous thromboembolism (VTE) prophylaxis is a strong recommendation after most surgeries, it is controversial in cardiac surgeries such as coronary artery bypass grafting (CABG), because of perceived low VTE incidence and increased bleeding risk. Prior studies may not have been adequately powered to study outcomes of VTE in this population. We sought to investigate the postoperative incidence and outcomes of CABG patients using a large national inpatient database.<\/jats:p>\n <\/jats:sec>\n \n Methods and Results<\/jats:title>\n \n We utilized the 2013 to 2014 National Inpatient Sample to identify all patients >18\u00a0years of age who underwent CABG (without concomitant valvular procedures), and had VTE during the hospital stay. We then compared clinically relevant outcomes in patients with and without VTE. We identified 331\u00a0950 CABG procedures. Of these, 1.3% (n=4205) had VTE. Patients with VTE were more likely to be older (mean 67.2\u00b110.4\u00a0years versus 65.2\u00b110.4\u00a0years,\n P<\/jats:italic>\n <0.001). VTE was associated with higher incidence of inpatient mortality (6.8% versus 1.7%; adjusted odds ratio 1.92 [95% CI 1.40\u20132.65];\n P<\/jats:italic>\n <0.001) and complications. VTE was also associated with higher cost (mean\u00b1SE $81\u00a0995\u00b1$923 versus $48\u00a0909\u00b1$55) and longer length of stay (mean\u00b1SE 17.06\u00b10.16\u00a0days versus 8.52\u00b10.01\u00a0days).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n Our analysis of >330\u00a0000 CABG procedures suggests that while postoperative VTE after CABG is rare, it is associated with increased morbidity and mortality. Randomized controlled trials are needed to identify optimal strategies for VTE prophylaxis in these patients.<\/jats:p>\n <\/jats:sec>","DOI":"10.1161\/jaha.119.013246","type":"journal-article","created":{"date-parts":[[2019,9,19]],"date-time":"2019-09-19T05:04:08Z","timestamp":1568869448000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":24,"title":["Association of Acute Venous Thromboembolism With In\u2010Hospital Outcomes of Coronary Artery Bypass Graft Surgery"],"prefix":"10.1161","volume":"8","author":[{"given":"Muhammad S.","family":"Panhwar","sequence":"first","affiliation":[{"name":"Tulane University School of Medicine","place":["New Orleans"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahazarin","family":"Ginwalla","sequence":"additional","affiliation":[{"name":"University Hospitals Cleveland Medical Center","place":["Cleveland"]},{"name":"Case Western Reserve University School of Medicine","place":["Cleveland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ankur","family":"Kalra","sequence":"additional","affiliation":[{"name":"Cleveland Clinic","place":["Cleveland"]},{"name":"Cleveland Clinic Lerner College of Medicine of Case Western Reserve University","place":["Cleveland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanush","family":"Gupta","sequence":"additional","affiliation":[{"name":"Albert Einstein College of Medicine","place":["New York"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dhaval","family":"Kolte","sequence":"additional","affiliation":[{"name":"Massachusetts General Hospital","place":["Boston"]},{"name":"Harvard Medical School","place":["Boston"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sahil","family":"Khera","sequence":"additional","affiliation":[{"name":"Icahn School of Medicine at Mount Sinai","place":["New York"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deepak L.","family":"Bhatt","sequence":"additional","affiliation":[{"name":"Brigham & Women's Hospital Heart & Vascular Center","place":["Boston"]},{"name":"Harvard Medical School","place":["Boston"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"III","given":"Joseph F.","family":"Sabik","sequence":"additional","affiliation":[{"name":"University Hospitals Cleveland Medical Center","place":["Cleveland"]},{"name":"Case Western Reserve University School of Medicine","place":["Cleveland"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0000000000002183"},{"key":"e_1_3_1_3_2","first-page":"401","article-title":"Venous thromboembolism in adult hospitalizations\u2014United States, 2007\u20132009","volume":"61","author":"Yusuf HR","year":"2012","unstructured":"Yusuf HR, Tsai J, Atrash HK, Boulet S, Grosse SD. 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