{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T21:08:33Z","timestamp":1792012113465,"version":"4.4.0"},"reference-count":53,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"18","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2019,9,17]]},"abstract":"<jats:sec xml:lang=\"en\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p xml:lang=\"en\">\n                      Body mass index and waist circumference (\n                      <jats:styled-content style=\"fixed-case\">WC<\/jats:styled-content>\n                      ) are commonly used metrics that reflect general obesity and abdominal obesity. However, the impact of general and abdominal obesity discrepancies on the risk for major adverse cardiac events (\n                      <jats:styled-content style=\"fixed-case\">MACE<\/jats:styled-content>\n                      ) is less explored.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Methods and Results<\/jats:title>\n                    <jats:p xml:lang=\"en\">\n                      The study population was derived from the Korean National Health Insurance Service\u2010Health Screening Cohort. Among 315\u00a0982 participants aged 40\u00a0years or older who underwent health examinations between 2008 and 2009, body mass index and\n                      <jats:styled-content style=\"fixed-case\">WC<\/jats:styled-content>\n                      were used to determine the obesity status. The participants were followed from January 1, 2010 for\n                      <jats:styled-content style=\"fixed-case\">MACE<\/jats:styled-content>\n                      until December 31, 2015. Cox proportional hazards models were used to evaluate the association of obesity and the risk of\n                      <jats:styled-content style=\"fixed-case\">MACE<\/jats:styled-content>\n                      . Compared with men who were not obese, those with abdominal obesity without general obesity (adjusted hazard ratio (\n                      <jats:styled-content style=\"fixed-case\">aHR<\/jats:styled-content>\n                      ) 1.29, 95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      1.16\u20131.43), and general and abdominal obesity (\n                      <jats:styled-content style=\"fixed-case\">aHR<\/jats:styled-content>\n                      1.20, 95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      1.12\u20131.29) had elevated risk of\n                      <jats:styled-content style=\"fixed-case\">MACE<\/jats:styled-content>\n                      , while those with general obesity without abdominal obesity (\n                      <jats:styled-content style=\"fixed-case\">aHR<\/jats:styled-content>\n                      1.06, 95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      0.98\u20131.16) did not. Similarly, women with abdominal obesity without general obesity (\n                      <jats:styled-content style=\"fixed-case\">aHR<\/jats:styled-content>\n                      1.13, 95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      1.03\u20131.24) and those with general and abdominal obesity (\n                      <jats:styled-content style=\"fixed-case\">aHR<\/jats:styled-content>\n                      1.15, 95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      1.06\u20131.25) had increased risk of\n                      <jats:styled-content style=\"fixed-case\">MACE<\/jats:styled-content>\n                      , while those with general obesity without abdominal obesity (\n                      <jats:styled-content style=\"fixed-case\">aHR<\/jats:styled-content>\n                      1.07, 95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      0.88\u20131.30) did not.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p xml:lang=\"en\">\n                      Abdominal obesity without general obesity was associated with an elevated risk of major cardiovascular outcomes while general obesity without abdominal obesity did not. Concurrent determination of body mass index and\n                      <jats:styled-content style=\"fixed-case\">WC<\/jats:styled-content>\n                      may be beneficial for the accurate determination of future cardiovascular risk.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/jaha.119.013471","type":"journal-article","created":{"date-parts":[[2019,9,4]],"date-time":"2019-09-04T05:02:08Z","timestamp":1567573328000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":70,"title":["Impact of Discrepancies in General and Abdominal Obesity on Major Adverse Cardiac Events"],"prefix":"10.1161","volume":"8","author":[{"given":"Daein","family":"Choi","sequence":"first","affiliation":[{"name":"Department of Biomedical Sciences Seoul National University Graduate School Seoul South Korea"},{"name":"Pyeongchang Health Center and County Hospital Pyeongchang South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seulggie","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Biomedical Sciences Seoul National University Graduate School Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joung Sik","family":"Son","sequence":"additional","affiliation":[{"name":"Department of Family Medicine Seoul National University Hospital Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang Woo","family":"Oh","sequence":"additional","affiliation":[{"name":"Department of Family Medicine Center for Obesity, Metabolism and Nutrition Dongguk University Ilsan Hospital Goyang South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang Min","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Biomedical Sciences Seoul National University Graduate School Seoul South Korea"},{"name":"Department of Family Medicine Seoul National University Hospital Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.114.008720"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(14)61682-2"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1995.03520300035033"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(11)60105-0"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)60318-4"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2006.06.004"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.304.5676.1413"},{"key":"e_1_3_1_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)67483-1"},{"key":"e_1_3_1_10_2","doi-asserted-by":"publisher","DOI":"10.1353\/hpu.2011.0166"},{"key":"e_1_3_1_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2008.12.068"},{"key":"e_1_3_1_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(87)91605-9"},{"key":"e_1_3_1_13_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a117385"},{"key":"e_1_3_1_14_2","doi-asserted-by":"publisher","DOI":"10.1053\/euhj.2001.2889"},{"key":"e_1_3_1_15_2","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/79.3.379"},{"key":"e_1_3_1_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2008.05.017"},{"key":"e_1_3_1_17_2","doi-asserted-by":"publisher","DOI":"10.1038\/ejcn.2013.61"},{"key":"e_1_3_1_18_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.280.21.1843"},{"key":"e_1_3_1_19_2","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.2009.28757"},{"key":"e_1_3_1_20_2","doi-asserted-by":"publisher","DOI":"10.1038\/ejcn.2009.139"},{"key":"e_1_3_1_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.nut.2005.01.007"},{"key":"e_1_3_1_22_2","first-page":"799","article-title":"Data resource profile: the national health information database of the National Health Insurance Service in South Korea","volume":"46","author":"Cheol Seong S","year":"2017","unstructured":"Cheol Seong S, Kim YY, Khang YH, Heon Park J, Kang HJ, Lee H, Do CH, Song JS, Hyon Bang J, Ha S, Lee EJ, Ae Shin S. 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