{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T16:07:33Z","timestamp":1792253253023,"version":"4.4.0"},"reference-count":45,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"9","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2020,5,5]]},"abstract":"<jats:sec xml:lang=\"en\">\n            <jats:title>Background<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              Mental health after spontaneous coronary artery dissection (\n              <jats:styled-content style=\"fixed-case\">SCAD<\/jats:styled-content>\n              ), a cause of myocardial infarction in young women, remains largely unexplored. We assessed the prevalence and severity of psychiatric symptoms after\n              <jats:styled-content style=\"fixed-case\">SCAD<\/jats:styled-content>\n              .\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Methods and Results<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              Individuals with confirmed\n              <jats:styled-content style=\"fixed-case\">SCAD<\/jats:styled-content>\n              who consented to the Mayo Clinic \u201cVirtual\u201d Multicenter\n              <jats:styled-content style=\"fixed-case\">SCAD<\/jats:styled-content>\n              Registry were sent the Posttraumatic Stress Disorder Diagnostic Scale for\n              <jats:italic>Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition<\/jats:italic>\n              , Patient Health Questionnaire\u20109, Generalized Anxiety Disorder\u20107, Anxiety Sensitivity Index, Connor\u2010Davidson Resilience Scale, 36\u2010Item Short\u2010Form Health Survey, and an\n              <jats:styled-content style=\"fixed-case\">SCAD<\/jats:styled-content>\n              \u2010specific questionnaire. Among 782 patients contacted, 512 surveys were returned. Most respondents were women (97.5%), with median age at time of\n              <jats:styled-content style=\"fixed-case\">SCAD<\/jats:styled-content>\n              and survey completion of 47 and 52\u00a0years, respectively. Eighty\u2010two percent had at least one trauma, with mild or more posttraumatic stress disorder symptoms in 28%. Symptoms of anxiety and depression were observed in 41% and 32%, respectively. On multivariable analysis, those of younger age at first\n              <jats:styled-content style=\"fixed-case\">SCAD<\/jats:styled-content>\n              and low resiliency scored higher on measures of trauma, anxiety, and depression. Those with higher anxiety sensitivity had more severe anxiety and posttraumatic stress disorder symptoms. Emotional and social quality of life was higher in those with high resiliency scores. Time from\n              <jats:styled-content style=\"fixed-case\">SCAD<\/jats:styled-content>\n              event to survey completion was associated with lower Generalized Anxiety Disorder\u20107 score severity.\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              Survivors of\n              <jats:styled-content style=\"fixed-case\">SCAD<\/jats:styled-content>\n              have significant rates of posttraumatic stress disorder, depression, and anxiety, which are associated with lower quality of life specifically among those with lower resiliency. Given the prevalence and potential impact, screening and treatment for the psychological distress is advised. Behavioral interventions targeted toward resiliency training may be beneficial for this patient population.\n            <\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/jaha.119.014372","type":"journal-article","created":{"date-parts":[[2020,4,28]],"date-time":"2020-04-28T09:09:05Z","timestamp":1588064945000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":81,"title":["Analysis of Posttraumatic Stress Disorder, Depression, Anxiety, and Resiliency Within the Unique Population of Spontaneous Coronary Artery Dissection Survivors"],"prefix":"10.1161","volume":"9","author":[{"given":"Alexis K.","family":"Johnson","sequence":"first","affiliation":[{"name":"Mayo Clinic Alix School of Medicine Rochester MN"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharonne N.","family":"Hayes","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Diseases Mayo Clinic College of Medicine and Science 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