{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T18:03:32Z","timestamp":1793037812893,"version":"4.5.0"},"reference-count":30,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2020,2,4]]},"abstract":"<jats:sec xml:lang=\"en\">\n            <jats:title>Background<\/jats:title>\n            <jats:p xml:lang=\"en\">The trajectory of ischemic stroke patients attributable to large vessel occlusion is fundamentally altered by endovascular thrombectomy. This study aimed to develop a nomogram for predicting 3\u2010month mortality risk in patients with ischemic stroke attributed to artery occlusion in anterior circulation who received successful endovascular thrombectomy treatment.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Methods and Results<\/jats:title>\n            <jats:p xml:lang=\"en\">Patients with successful endovascular thrombectomy (modified Thrombolysis in Cerebral Infarction IIb or III) were enrolled from a multicenter registry as the training cohort. Step\u2010wise logistic regression with Akaike information criterion was utilized to establish the best\u2010fit nomogram. The discriminative value of the nomogram was tested by concordance index. An additional 224 patients from 2 comprehensive stroke centers were prospectively recruited as the test cohort for validating the new nomogram. Altogether, 417 patients were enrolled in the training cohort. Age (odds ratio [OR], 1.07; 95% CI, 1.03\u22121.10), poor pretreatment collateral status (OR, 2.13; 95% CI, 1.18\u22123.85), baseline blood glucose level (OR, 1.12; 95% CI, 1.04\u22121.21), symptomatic intracranial hemorrhage (OR, 9.51; 95% CI, 4.54\u221219.92), and baseline National Institutes of Health Stroke Scale score (OR, 1.08; 95% CI, 1.03\u22121.12) were associated with mortality and were incorporated in the nomogram. The c\u2010index of the nomogram was 0.835 (95% CI, 0.785\u20130.885) in the training cohort and 0.758 (95% CI, 0.667\u20130.849) in the test cohort.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p xml:lang=\"en\">The nomogram, composed of age, pretreatment collateral status, baseline blood glucose level, symptomatic intracranial hemorrhage, and baseline National Institutes of Health Stroke Scale score, may predict risk of mortality in patients with ischemic stroke and treated successfully with endovascular thrombectomy.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/jaha.119.014899","type":"journal-article","created":{"date-parts":[[2020,1,24]],"date-time":"2020-01-24T10:00:33Z","timestamp":1579860033000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":68,"title":["Nomogram to Predict Mortality of Endovascular Thrombectomy for Ischemic Stroke Despite Successful Recanalization"],"prefix":"10.1161","volume":"9","author":[{"given":"Xiaohao","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Neurology Jinling Hospital Medical School of Nanjing University Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kang","family":"Yuan","sequence":"additional","affiliation":[{"name":"Department of Neurology Jinling Hospital Nanjing Medical University Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huaiming","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Neurology Jinling Hospital Medical School of Nanjing University Nanjing China"},{"name":"Department of Neurology The 89th Hospital of The People's Liberation Army Weifang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pengyu","family":"Gong","sequence":"additional","affiliation":[{"name":"Department of Neurology Nanjing First Hospital Nanjing Medical University Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teng","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Neurology Nanjing First Hospital Nanjing Medical University Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Xie","sequence":"additional","affiliation":[{"name":"Department of Neurology Jinling Hospital Medical School of Nanjing University Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Sheng","sequence":"additional","affiliation":[{"name":"Department of Neurology Jiangsu Provincial Second Chinese Medicine Hospital Second Affiliated Hospital of Nanjing University of Chinese Medicine Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dezhi","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Neurology Shanghai General Hospital Shanghai Jiao Tong University School of Medicine Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinfeng","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Neurology Jinling Hospital Medical School of Nanjing University Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gelin","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Neurology Jinling Hospital Medical School of Nanjing University Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1503780"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1414792"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1414905"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1411587"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1415061"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000258112.14918.24"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A2709"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.114.005603"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1136\/neurintsurg-2014-011525"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2018.04.042"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.109.561431"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.113.002796"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.113.001050"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamasurg.2015.4516"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(14)70325-4"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.118.023316"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.117.018427"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1159\/000478667"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.24.1.35"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.115.010049"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.113.001972"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1177\/0272989X06295361"},{"key":"e_1_3_2_24_2","volume-title":"Handbook of Statistics v23: Advances in Survival Analysis","author":"D'Agostino R","year":"2004","unstructured":"D'Agostino R, Nam B. Evaluation of the performance of survival analysis models: discrimination and calibration measures. In: Balakrishnan N, Rao CR, eds. Handbook of Statistics v23: Advances in Survival Analysis. Amsterdam, the Netherlands: Elsevier; 2004."},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1161\/STR.0000000000000158"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A3707"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1136\/neurintsurg-2014-011351"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jcbfm.9600454"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.110.604603"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.113.004072"},{"key":"e_1_3_2_31_2","first-page":"382","article-title":"TIMI, TIBI, TICI: I came, I saw, I got confused","volume":"28","author":"Tomsick T","year":"2007","unstructured":"Tomsick T. TIMI, TIBI, TICI: I came, I saw, I got confused. AJNR Am J Neuroradiol. 2007;28:382\u2013384.","journal-title":"AJNR Am J Neuroradiol"}],"container-title":["Journal of the American Heart Association"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/JAHA.119.014899","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T11:37:51Z","timestamp":1715600271000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/JAHA.119.014899"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2,4]]},"references-count":30,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2020,2,4]]}},"alternative-id":["10.1161\/JAHA.119.014899"],"URL":"https:\/\/doi.org\/10.1161\/jaha.119.014899","relation":{},"ISSN":["2047-9980"],"issn-type":[{"value":"2047-9980","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,2,4]]},"assertion":[{"value":"2019-10-09","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-01-02","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-01-24","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e014899"}}