{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T11:19:06Z","timestamp":1790507946740,"version":"4.1.0"},"reference-count":34,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2020,3,17]]},"abstract":"\n Background<\/jats:title>\n \n Patients who survive acute myocardial infarction (\n AMI<\/jats:styled-content>\n ) are at high risk for recurrence. We determined whether rehospitalizations after\n AMI<\/jats:styled-content>\n further increased risk of recurrent\n AMI<\/jats:styled-content>\n .\n <\/jats:p>\n <\/jats:sec>\n \n Methods and Results<\/jats:title>\n \n The study included Medicare fee\u2010for\u2010service patients aged \u226565\u00a0years discharged alive after\n AMI<\/jats:styled-content>\n from acute\u2010care hospitals in fiscal years 2009\u20132014. The outcome was recurrent\n AMI<\/jats:styled-content>\n within 1\u00a0year of the index\n AMI<\/jats:styled-content>\n . The Clinical Classifications Software (\n CCS<\/jats:styled-content>\n ) was used to classify rehospitalizations into disease categories. A Cox regression model was fit accounting for\n CCS<\/jats:styled-content>\n \u2010specific hospitalizations as time\u2010varying variables and patient characteristics at discharge for the index\n AMI<\/jats:styled-content>\n , adjusting for the competing risk of death. The rate of 1\u2010year recurrent\n AMI<\/jats:styled-content>\n was 5.3% (95%\n CI<\/jats:styled-content>\n , 5.27%\u20135.41%), and median (interquartile range) time from discharge to recurrent\n AMI<\/jats:styled-content>\n was 115 (34\u2013230) days. Eleven disease categories (diabetes mellitus, anemia, hypertension, coronary atherosclerosis, chest pain, heart failure, pneumonia, chronic obstructive pulmonary disease, gastrointestinal hemorrhage, renal failure, complication of implant or graft) were associated with increased risk of recurrent\n AMI<\/jats:styled-content>\n . Septicemia was associated with lower recurrence risk. Hazard ratios ranged from 1.6 (95%\n CI<\/jats:styled-content>\n , 1.55\u20131.70, heart failure) to 1.1 (95%\n CI<\/jats:styled-content>\n , 1.04\u20131.25, pneumonia) to 0.6 (95%\n CI<\/jats:styled-content>\n , 0.58\u20130.71, septicemia).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n Patient risk of recurrent\n AMI<\/jats:styled-content>\n changed based on the occurrence of hospitalizations after the index\n AMI<\/jats:styled-content>\n . Improving post\u2013acute care to prevent unplanned rehospitalizations, especially rehospitalizations for chronic diseases, and extending the focus of outcomes measures to condition\u2010specific rehospitalizations within 30\u00a0days and beyond is important for the secondary prevention of\n AMI<\/jats:styled-content>\n .\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1161\/jaha.119.014907","type":"journal-article","created":{"date-parts":[[2020,3,14]],"date-time":"2020-03-14T05:00:23Z","timestamp":1584162023000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":33,"title":["Association Between Subsequent Hospitalizations and Recurrent Acute Myocardial Infarction Within 1 Year After Acute Myocardial Infarction"],"prefix":"10.1161","volume":"9","author":[{"given":"Yun","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Biostatistics Harvard T.H. 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