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This transformation has been supported by numerous well\u2010designed randomized trials, but they have centered almost entirely on devices and procedures. Outside this scope of focus, however, myriad aspects of therapy and management for patients with\n            <jats:styled-content style=\"fixed-case\">VHD<\/jats:styled-content>\n            have either no guidelines or recommendations based only on expert opinion and observational studies. Further, research in\n            <jats:styled-content style=\"fixed-case\">VHD<\/jats:styled-content>\n            has often failed to engage patients to inform study design and identify research questions of greatest importance and relevance from a patient perspective. Accordingly, the National Heart, Lung, and Blood Institute convened a Working Group on Patient\u2010Centered Research in Valvular Heart Disease, composed of clinician and research experts and patient advocacy experts to identify gaps and barriers to research in\n            <jats:styled-content style=\"fixed-case\">VHD<\/jats:styled-content>\n            and identify research priorities. While recognizing that important research remains to be done to test the safety and efficacy of devices and procedures to treat\n            <jats:styled-content style=\"fixed-case\">VHD<\/jats:styled-content>\n            , we intentionally focused less attention on these areas of research as they are more commonly pursued and supported by industry. Herein, we present the patient\u2010centered research gaps, barriers, and priorities in\n            <jats:styled-content style=\"fixed-case\">VHD<\/jats:styled-content>\n            and organized our report according to the \u201cpatient journey,\u201d including access to care, screening and diagnosis, preprocedure therapy and management, decision making when a procedure is contemplated (clinician and patient perspectives), and postprocedure therapy and management. It is hoped that this report will foster collaboration among diverse stakeholders and highlight for funding bodies the pressing patient\u2010centered research gaps, opportunities, and priorities in\n            <jats:styled-content style=\"fixed-case\">VHD<\/jats:styled-content>\n            in order to produce impactful patient\u2010centered research that will inform and improve patient\u2010centered policy and care.\n          <\/jats:p>","DOI":"10.1161\/jaha.119.015975","type":"journal-article","created":{"date-parts":[[2020,4,24]],"date-time":"2020-04-24T09:02:11Z","timestamp":1587718931000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":43,"title":["Priorities for Patient\u2010Centered Research in Valvular Heart Disease: A Report From the National Heart, Lung, and Blood Institute Working 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