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This systematic review aims to (1) quantify the number of cases and indications for\n                      <jats:styled-content style=\"fixed-case\">ECLS<\/jats:styled-content>\n                      in women during the peripartum period reported in the literature and (2) report maternal and fetal complications and outcomes associated with peripartum\n                      <jats:styled-content style=\"fixed-case\">ECLS<\/jats:styled-content>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Methods and Results<\/jats:title>\n                    <jats:p xml:lang=\"en\">\n                      This review was registered in\n                      <jats:styled-content style=\"fixed-case\">PROSPERO<\/jats:styled-content>\n                      (\n                      <jats:styled-content style=\"fixed-case\">CRD<\/jats:styled-content>\n                      42018108142).\n                      <jats:styled-content style=\"fixed-case\">MEDLINE<\/jats:styled-content>\n                      , Embase, and\n                      <jats:styled-content style=\"fixed-case\">CINAHL<\/jats:styled-content>\n                      were searched for case reports, case series, and studies reporting cases of\n                      <jats:styled-content style=\"fixed-case\">ECLS<\/jats:styled-content>\n                      during the peripartum period that reported one or more of the following outcomes: maternal survival, maternal complications, fetal survival, and\/or fetal complications. Qualitative assessment of 221 publications evaluated the number of cases, clinical details, and maternal and fetal outcomes of\n                      <jats:styled-content style=\"fixed-case\">ECLS<\/jats:styled-content>\n                      during the peripartum period. There were 358 women included and 68 reported fetal outcomes in cases where the mother was pregnant at the time of cannulation. The aggregate maternal survival at 30\u00a0days was 270 (75.4%) and at 1\u00a0year was 266 (74.3%); fetal survival was 44 (64.7%). The most common indications for\n                      <jats:styled-content style=\"fixed-case\">ECLS<\/jats:styled-content>\n                      overall in pregnancy included acute respiratory distress syndrome 177 (49.4%), cardiac failure 67 (18.7%), and cardiac arrest 57 (15.9%). The most common maternal complications included mild to moderate bleeding 66 (18.4%), severe bleeding requiring surgical intervention 48 (13.4%), and intracranial neurologic morbidity 19 (5.3%). The most commonly reported fetal complications included preterm delivery 33 (48.5%) and neonatal intensive care unit admission 19 (27.9%).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p xml:lang=\"en\">\n                      Reported rates of survival in\n                      <jats:styled-content style=\"fixed-case\">ECLS<\/jats:styled-content>\n                      in pregnant and postpartum women are high and major complications relatively low.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/jaha.119.016072","type":"journal-article","created":{"date-parts":[[2020,6,24]],"date-time":"2020-06-24T05:27:03Z","timestamp":1592976423000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":162,"title":["Extracorporeal Life Support in Pregnancy: A Systematic Review"],"prefix":"10.1161","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4107-882X","authenticated-orcid":false,"given":"Emily E.","family":"Naoum","sequence":"first","affiliation":[{"name":"Department of Anesthesiology University of Michigan Ann Arbor MI"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Chalupka","sequence":"additional","affiliation":[{"name":"Department of Anesthesia, Critical Care and Pain Medicine Massachusetts General Hospital Boston MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan","family":"Haft","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery University of Michigan Ann Arbor MI"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"MacEachern","sequence":"additional","affiliation":[{"name":"Taubman Health Sciences Library University of Michigan Ann Arbor MI"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cosmas J. 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