{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T16:05:32Z","timestamp":1791475532011,"version":"4.3.4"},"reference-count":43,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"7","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2021,4,6]]},"abstract":"<jats:sec xml:lang=\"en\">\n            <jats:title>Background<\/jats:title>\n            <jats:p xml:lang=\"en\">Less than 40% of acute stroke patients have computed tomography (CT) imaging performed within 25\u00a0minutes of hospital arrival. We aimed to examine the race\u2010ethnic and sex differences in door\u2010to\u2010CT (DTCT) \u226425\u00a0minutes in the FSR (Florida Stroke Registry).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Methods and Results<\/jats:title>\n            <jats:p xml:lang=\"en\">Data were collected from 2010 to 2018 for 63\u00a0265 patients with acute ischemic stroke from the FSR and secondary analysis was performed on 15\u00a0877 patients with intravenous tissue plasminogen activator\u2010treated ischemic stroke. Generalized estimating equation models were used to determine predictors of DTCT \u226425. DTCT \u226425 was achieved in 56% of cases of suspected acute stroke, improving from 36% in 2010 to 72% in 2018. Women (odds ratio [OR], 0.90; 95% CI, 0.87\u20130.93) and Black (OR, 0.88; CI, 0.84\u20130.94) patients who had strokes were less likely, and Hispanic patients more likely (OR, 1.07; CI, 1.01\u20131.14), to achieve DTCT \u226425. In a secondary analysis among intravenous tissue plasminogen activator\u2010treated patients, 81% of patients achieved DTCT \u226425. In this subgroup, women were less likely to receive DTCT \u226425 (0.85, 0.77\u20130.94) whereas no significant differences were observed by race or ethnicity.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p xml:lang=\"en\">In the FSR, there was considerable improvement in acute stroke care metric DTCT \u226425 in 2018 in comparison to 2010. However, sex and race\u2010ethnic disparities persist and require further efforts to improve performance and reduce these disparities.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/jaha.120.017543","type":"journal-article","created":{"date-parts":[[2021,3,31]],"date-time":"2021-03-31T09:51:17Z","timestamp":1617184277000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":26,"title":["Sex and Race\u2010Ethnic Disparities in Door\u2010to\u2010CT Time in Acute Ischemic Stroke: The Florida Stroke Registry"],"prefix":"10.1161","volume":"10","author":[{"given":"Sai P.","family":"Polineni","sequence":"first","affiliation":[{"name":"Department of Neurology University of Miami Miller School of Medicine Miami FL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enmanuel J.","family":"Perez","sequence":"additional","affiliation":[{"name":"Department of Neurology Washington University in St. Louis MO"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kefeng","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Miami Miller School of Medicine Miami FL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina M.","family":"Gutierrez","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Miami Miller School of Medicine Miami FL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey","family":"Walker","sequence":"additional","affiliation":[{"name":"American Heart Association Southeast Marietta GA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dianne","family":"Foster","sequence":"additional","affiliation":[{"name":"American Heart Association Southeast Marietta GA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuanhui","family":"Dong","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Miami Miller School of Medicine Miami FL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0285-825X","authenticated-orcid":false,"given":"Negar","family":"Asdaghi","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Miami Miller School of Medicine Miami FL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3667-2792","authenticated-orcid":false,"given":"Jose G.","family":"Romano","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Miami Miller School of Medicine Miami FL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4629-684X","authenticated-orcid":false,"given":"Ralph L.","family":"Sacco","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Miami Miller School of Medicine Miami FL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7115-9815","authenticated-orcid":false,"given":"Tatjana","family":"Rundek","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Miami Miller School of Medicine Miami FL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"for the Florida Stroke Registry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000659"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1161\/STR.0000000000000158"},{"key":"e_1_3_2_4_2","unstructured":"American Stroke Association . 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