{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T20:03:58Z","timestamp":1778097838360,"version":"3.51.4"},"reference-count":23,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"24","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2020,12,15]]},"abstract":"<jats:sec xml:lang=\"en\">\n            <jats:title>Background<\/jats:title>\n            <jats:p xml:lang=\"en\">It has been reported that atrial fibrillation (AF) may contribute to impairment of baroreflex sensitivity (BRS). However, the difference of BRS between patients with persistent AF (PeAF) and those with paroxysmal AF (PAF) is unknown. We tested the hypothesis that patients with PeAF have a more impaired BRS compared with those with PAF.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Methods and Results<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              From October 2015 onwards, a total of 67 patients (14 women [20.9%]; mean age 65.2\u00b110.1\u00a0years) with PAF (n=46, 68.7%) and PeAF (n=21, 31.3%), who underwent catheter ablation, were prospectively enrolled. The baseline BRS was evaluated during sinus rhythm. The baseline BRS in patients with PeAF was significantly lower than those with PAF (2.97 [0.52\u20136.62] ms\/mm\u00a0Hg versus 4.70 [2.36\u20138.37] ms\/mm\u00a0Hg,\n              <jats:italic>P<\/jats:italic>\n              =0.047). The BRS was significantly depressed after catheter ablation in all the patients (4.66 [1.80\u20137.37] ms\/mm\u00a0Hg versus 0.55 [\u22120.15 to 1.22] ms\/mm\u00a0Hg,\n              <jats:italic>P<\/jats:italic>\n              &lt;0.001). However, the depression of BRS because of catheter ablation appeared attenuated in patients with PeAF when compared with those with PAF. The number of patients who did not show depression of BRS was significantly greater, that is, patients with PeAF (3\/12, 25%) than those with PAF (0\/46, 0%,\n              <jats:italic>P<\/jats:italic>\n              &lt;0.01).\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p xml:lang=\"en\">Our findings demonstrated that the baseline BRS was more depressed in patients with PeAF compared with PAF. Catheter ablation depressed BRS irrespective of the type of AF, with a greater effect in patients with PAF than PeAF.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/jaha.120.018019","type":"journal-article","created":{"date-parts":[[2020,12,2]],"date-time":"2020-12-02T13:16:58Z","timestamp":1606915018000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":17,"title":["Baroreflex Sensitivity in Patients With Atrial Fibrillation"],"prefix":"10.1161","volume":"9","author":[{"given":"Miho","family":"Miyoshi","sequence":"first","affiliation":[{"name":"Department of Cardiology and Clinical Examination Faculty of Medicine Oita University Yufu\u2010City Oita Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2451-5845","authenticated-orcid":false,"given":"Hidekazu","family":"Kondo","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Clinical Examination 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