{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T15:43:43Z","timestamp":1792511023404,"version":"4.5.0"},"reference-count":23,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2021,1,5]]},"abstract":"<jats:sec xml:lang=\"en\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p xml:lang=\"en\">In athletes with ventricular arrhythmias (VA) and otherwise unremarkable clinical findings, cardiac magnetic resonance (CMR) may reveal concealed pathological substrates. The aim of this multicenter study was to evaluate which VA characteristics predicted CMR abnormalities.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Methods and Results<\/jats:title>\n                    <jats:p xml:lang=\"en\">\n                      We enrolled 251 consecutive competitive athletes (74% males, median age 25 [17\u201039] years) who underwent CMR for evaluation of VA. We included athletes with &gt;100 premature ventricular beats\/24 h or \u22651 repetitive VA (couplets, triplets, or nonsustained ventricular tachycardia) on 12\u2010lead 24\u2010hour ambulatory ECG monitoring and negative family history, ECG, and echocardiogram. Features of VA that were evaluated included number, morphology, repetitivity, and response to exercise testing. Left\u2010ventricular late gadolinium\u2010enhancement was documented by CMR in 28 (11%) athletes, mostly (n=25) with a subepicardial\/midmyocardial stria pattern. On 24\u2010hour ECG monitoring, premature ventricular beats with multiple morphologies or with right\u2010bundle\u2010branch\u2010block and intermediate\/superior axis configuration were documented in 25 (89%) athletes with versus 58 (26%) without late gadolinium\u2010enhancement (\n                      <jats:italic>P<\/jats:italic>\n                      &lt;0.001). More than 3300 premature ventricular beats were recorded in 4 (14%) athletes with versus 117 (53%) without positive CMR (\n                      <jats:italic>P<\/jats:italic>\n                      &lt;0.001). At exercise testing, nonsustained ventricular tachycardia occurred at peak of exercise in 8 (29%) athletes with late gadolinium\u2010enhancement (polymorphic in 6\/8, 75%) versus 17 athletes (8%) without late gadolinium\u2010enhancement (\n                      <jats:italic>P<\/jats:italic>\n                      =0.002), (\n                      <jats:italic>P<\/jats:italic>\n                      &lt;0.0001). At multivariable analysis, all 3 parameters independently correlated with CMR abnormalities.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p xml:lang=\"en\">In athletes with apparently idiopathic VA, simple characteristics such as number and morphology of premature ventricular beats on 12\u2010lead 24\u2010hour ambulatory ECG monitoring and response to exercise testing predicted the presence of concealed myocardial abnormalities on CMR. These findings may help cost\u2010effective CMR prescription.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/jaha.120.018206","type":"journal-article","created":{"date-parts":[[2020,12,31]],"date-time":"2020-12-31T05:27:18Z","timestamp":1609392438000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":45,"title":["Predictors of Left Ventricular Scar Using Cardiac Magnetic Resonance in Athletes With Apparently Idiopathic Ventricular Arrhythmias"],"prefix":"10.1161","volume":"10","author":[{"given":"Cinzia","family":"Crescenzi","sequence":"first","affiliation":[{"name":"Division of Cardiology Policlinico Casilino Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3578-0583","authenticated-orcid":false,"given":"Alessandro","family":"Zorzi","sequence":"additional","affiliation":[{"name":"Department of Cardiac, Thoracic and Vascular Sciences and Public Health University of Padova Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teresina","family":"Vessella","sequence":"additional","affiliation":[{"name":"Center for Sports Medicine ULSS2 Marca Trevigiana Treviso Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annamaria","family":"Martino","sequence":"additional","affiliation":[{"name":"Division of Cardiology Policlinico Casilino Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Germana","family":"Panattoni","sequence":"additional","affiliation":[{"name":"Division of Cardiology Policlinico Casilino Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7842-6202","authenticated-orcid":false,"given":"Alberto","family":"Cipriani","sequence":"additional","affiliation":[{"name":"Department of Cardiac, Thoracic and Vascular Sciences and Public Health University of Padova Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuel","family":"De Lazzari","sequence":"additional","affiliation":[{"name":"Department of Cardiac, Thoracic and Vascular Sciences and Public Health University of Padova Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martina","family":"Perazzolo Marra","sequence":"additional","affiliation":[{"name":"Department of Cardiac, Thoracic and Vascular Sciences and Public Health University of Padova Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Armando","family":"Fusco","sequence":"additional","affiliation":[{"name":"Department of Radiology Policlinico Casilino Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luigi","family":"Sciarra","sequence":"additional","affiliation":[{"name":"Division of Cardiology Policlinico Casilino Rome 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