{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T19:22:04Z","timestamp":1788636124874,"version":"build-2803163510"},"reference-count":27,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"7","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2021,4,6]]},"abstract":"<jats:sec xml:lang=\"en\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p xml:lang=\"en\">Esophageal thermal injury (ETI) is a byproduct of atrial fibrillation (AF) ablation using thermal sources. The most severe form of ETI is represented by atrioesophageal fistula, which has a high mortality rate. Late gadolinium enhancement (LGE) magnetic resonance imaging (MRI) allows identification of ETI. Hence, we sought to evaluate the utility of LGE\u2010MRI as a method to identify ETI across the entire spectrum of severity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Methods and Results<\/jats:title>\n                    <jats:p xml:lang=\"en\">All AF radiofrequency ablations performed at the University of Utah between January 2009 and December 2017 were reviewed. Patients with LGE\u2010MRI within 24 hours following AF ablation as well as patients who had esophagogastroduodenoscopy in addition to LGE\u2010MRI were identified. An additional patient with atrioesophageal fistula who had AF ablation at a different institution and had MRI and esophagogastroduodenoscopy at the University of Utah was identified. A total of 1269 AF radiofrequency ablations were identified. ETI severity was classified on the basis of esophageal LGE pattern (none, 60.9%; mild, 27.5%; moderate, 9.9%; severe, 1.7%). ETI resolved in most patients who underwent repeat LGE\u2010MRI at 3\u00a0months. All patients with esophagogastroduodenoscopy\u2010confirmed ETI had moderate\u2010to\u2010severe LGE 24 hours after ablation MRI. Moderate\u2010to\u2010severe LGE had 100% sensitivity and 58.1% specificity in detecting ETI, and a negative predictive value of 100%. Atrioesophageal fistula was visualized by both computed tomography and LGE\u2010MRI in one patient.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p xml:lang=\"en\">LGE\u2010MRI is useful in detecting and characterizing ETI across the entire severity spectrum. LGE\u2010MRI exhibits an extremely high sensitivity and negative predictive value in screening for ETI after AF ablation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/jaha.120.018924","type":"journal-article","created":{"date-parts":[[2021,3,24]],"date-time":"2021-03-24T05:59:11Z","timestamp":1616565551000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":11,"title":["Late Gadolinium Enhancement Magnetic Resonance Imaging Evaluation of Post\u2013Atrial Fibrillation Ablation Esophageal Thermal Injury Across the Spectrum of Severity"],"prefix":"10.1161","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1395-8707","authenticated-orcid":false,"given":"Qussay","family":"Marashly","sequence":"first","affiliation":[{"name":"Department of Internal Medicine University of Utah School of Medicine Salt Lake City UT"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chaitra","family":"Gopinath","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine University of Kansas Medical Center\u2013Wichita Wichita KS"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex","family":"Baher","sequence":"additional","affiliation":[{"name":"Metropolitan Heart and Vascular Institute Coon Rapids MN"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madan","family":"Acharya","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine University of Utah School of Medicine Salt Lake City UT"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5094-6975","authenticated-orcid":false,"given":"Mobin","family":"Kheirkhahan","sequence":"additional","affiliation":[{"name":"Department of Medicine Northwestern University Chicago IL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin","family":"Hardisty","sequence":"additional","affiliation":[{"name":"VA Informatics and Computing Infrastructure (VINCI) Northwestern University Chicago IL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3920-2876","authenticated-orcid":false,"given":"Mossab","family":"Aljuaid","sequence":"additional","affiliation":[{"name":"Cardiovascular Center Northwestern University Chicago IL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ibrahim","family":"Tawhari","sequence":"additional","affiliation":[{"name":"Division of Nephrology and Hypertension Feinberg School of Medicine Northwestern University Chicago IL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Ibrahim","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine University of Utah School of Medicine Salt Lake City UT"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8568-7635","authenticated-orcid":false,"given":"Alan K.","family":"Morris","sequence":"additional","affiliation":[{"name":"Utah Center for Advanced Imaging Research (UCAIR) University of Utah Salt Lake City UT"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eugene G.","family":"Kholmovski","sequence":"additional","affiliation":[{"name":"Utah Center for Advanced Imaging Research (UCAIR) University of Utah Salt Lake City UT"},{"name":"Department of Radiology and Imaging Sciences University of Utah Salt Lake City UT"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brent D.","family":"Wilson","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine University of Utah School of Medicine Salt Lake City UT"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nassir F.","family":"Marrouche","sequence":"additional","affiliation":[{"name":"Section of Cardiac Electrophysiology Tulane University Heart &amp; 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