{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T21:10:37Z","timestamp":1793135437335,"version":"4.5.0"},"reference-count":45,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"16","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2021,8,17]]},"abstract":"<jats:sec xml:lang=\"en\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p xml:lang=\"en\">We aimed to understand the characteristics and outcomes of patients readmitted with a recurrent myocardial infarction (RMI) within 90\u00a0days of discharge after an acute myocardial infarction (early RMI).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Methods and Results<\/jats:title>\n                    <jats:p xml:lang=\"en\">\n                      We analyzed the timing of reinfarction, etiology, and outcome for all patients admitted with an early RMI within 90\u00a0days of discharge after an acute myocardial infarction between January 1, 2010 and January 1, 2017. We identified 6626 admissions for acute myocardial infarction (index myocardial infarction) which led to 168 cases of RMI within 90\u00a0days of discharge. The mean patient age was 65.1\u00b113.1\u00a0years, and 37% were women. The 90\u2010day probability of readmission with an early RMI was 2.5%. Black race, medical management, higher troponin T, and shorter length of stay were independent predictors of early RMI. Medically managed group had a higher risk for early RMI compared with percutaneous coronary intervention (\n                      <jats:italic>P<\/jats:italic>\n                      =0.04) or coronary artery bypass grafting (\n                      <jats:italic>P<\/jats:italic>\n                      =0.2). Predominant mechanisms for reinfarction were stent thrombosis (17%), disease progression (12%), and unchanged coronary artery disease (11%). At 5\u00a0years, the all\u2010cause mortality rate for patients with an early RMI was 49% (95% CI, 40%\u201357%) compared with 22% (95% CI, 21%\u201323%) for patients without an early RMI (\n                      <jats:italic>P<\/jats:italic>\n                      &lt;0.0001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p xml:lang=\"en\">Early RMI is a life\u2010threatening condition with nearly 50% mortality within 5\u00a0years. Stent\u2010related events and progression in coronary artery disease account for most early RMI. Medication compliance, aggressive risk factor management, and care transitions should be the cornerstone in preventing early RMI.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/jaha.120.019270","type":"journal-article","created":{"date-parts":[[2021,8,2]],"date-time":"2021-08-02T04:59:12Z","timestamp":1627880352000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":57,"title":["Characteristics and Outcomes of Early Recurrent Myocardial Infarction After Acute Myocardial Infarction"],"prefix":"10.1161","volume":"10","author":[{"given":"Raunak","family":"Nair","sequence":"first","affiliation":[{"name":"Cleveland Clinic Heart, Vascular and Thoracic Institute Cleveland OH"},{"name":"Cleveland Clinic Heart, Vascular and Thoracic Institute Center for Healthcare Delivery Innovation Cleveland OH"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Johnson","sequence":"additional","affiliation":[{"name":"Cleveland Clinic Heart, Vascular and Thoracic Institute Center for Healthcare Delivery Innovation Cleveland OH"},{"name":"University Cardiology Associates Augusta GA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathleen","family":"Kravitz","sequence":"additional","affiliation":[{"name":"Cleveland Clinic Heart, Vascular and Thoracic Institute Cleveland OH"},{"name":"Cleveland Clinic Heart, Vascular and Thoracic Institute Center for Healthcare Delivery Innovation Cleveland OH"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chetan","family":"Huded","sequence":"additional","affiliation":[{"name":"Cleveland Clinic Heart, Vascular and Thoracic Institute Center for Healthcare Delivery Innovation Cleveland OH"},{"name":"Saint Luke's Mid America Heart Institute Kansas City MO"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeevanantham","family":"Rajeswaran","sequence":"additional","affiliation":[{"name":"Cleveland Clinic Heart, Vascular and Thoracic Institute Cleveland OH"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moses","family":"Anabila","sequence":"additional","affiliation":[{"name":"Cleveland Clinic Heart, Vascular and Thoracic Institute Cleveland OH"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9839-3567","authenticated-orcid":false,"given":"Eugene","family":"Blackstone","sequence":"additional","affiliation":[{"name":"Cleveland Clinic Heart, Vascular and Thoracic Institute Cleveland OH"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4410-2677","authenticated-orcid":false,"given":"Venu","family":"Menon","sequence":"additional","affiliation":[{"name":"Cleveland Clinic Heart, Vascular and Thoracic Institute Cleveland OH"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. 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