{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T07:48:45Z","timestamp":1790668125922,"version":"4.1.0"},"reference-count":32,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"8","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2021,4,20]]},"abstract":"<jats:sec xml:lang=\"en\">\n            <jats:title>Background<\/jats:title>\n            <jats:p xml:lang=\"en\">Although antiplatelet therapy (APT) has been recommended to balance ischemic\u2010bleeding risks, it has been left to an individualized decision\u2010making based on physicians' perspectives before non\u2010cardiac surgery. The study aimed to assess the advantages of a consensus among physicians, surgeons, and anesthesiologists on continuation and regimen of preoperative APT in patients with coronary drug\u2010eluting stents.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Methods and Results<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              A total of 3582 adult patients undergoing non\u2010cardiac surgery after percutaneous coronary intervention with second\u2010generation stents was retrospectively included from a multicenter cohort. Physicians determined whether APT should be continued or discontinued for a recommended period before non\u2010cardiac surgery. There were 3103 patients who complied with a consensus decision. Arbitrary APT, not based on a consensus decision, was associated with urgent surgery, high bleeding risk of surgery, female sex, and dual APT at the time of preoperative evaluation. Arbitrary APT independently increased the net clinical adverse event (adjusted odds ratio [OR\n              <jats:sub>adj<\/jats:sub>\n              ], 1.98; 95% CI, 1.98\u20133.11), major adverse cardiac event (OR\n              <jats:sub>adj<\/jats:sub>\n              , 3.11; 95% CI, 1.31\u20137.34), and major bleeding (OR\n              <jats:sub>adj<\/jats:sub>\n              , 2.34; 95% CI, 1.45\u20133.76) risks. The association was consistently noted, irrespective of the surgical risks, recommendations, and practice on discontinuation of APT.\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p xml:lang=\"en\">Most patients were treated in agreement with a consensus decision about preoperative APT based on a referral system among physicians, surgeons, and anesthesiologists. The risk of perioperative adverse events increased if complying with a consensus decision was failed.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Registration<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              URL:\n              <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/www.clinicaltrials.gov\">https:\/\/www.clinicaltrials.gov<\/jats:ext-link>\n              ; Unique identifier: NCT03908463.\n            <\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/jaha.120.020079","type":"journal-article","created":{"date-parts":[[2021,4,10]],"date-time":"2021-04-10T09:38:35Z","timestamp":1618047515000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":11,"title":["Consensus Decision\u2010Making for the Management of Antiplatelet Therapy before Non\u2010Cardiac Surgery in Patients Who Underwent Percutaneous Coronary Intervention With Second\u2010Generation Drug\u2010Eluting Stents: A Cohort Study"],"prefix":"10.1161","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5226-7290","authenticated-orcid":false,"given":"Choongki","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Cardiology Ewha Womans University College of Medicine Seoul Hospital Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2263-3274","authenticated-orcid":false,"given":"Jung\u2010Sun","family":"Kim","sequence":"additional","affiliation":[{"name":"Division of Cardiology Department of Internal Medicine Severance Cardiovascular Hospital Yonsei University College of Medicine Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5030-952X","authenticated-orcid":false,"given":"Hyeongsoo","family":"Kim","sequence":"additional","affiliation":[{"name":"Division of Cardiology Department of Internal Medicine Severance Cardiovascular Hospital Yonsei University College of Medicine Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1528-2739","authenticated-orcid":false,"given":"Sung Gyun","family":"Ahn","sequence":"additional","affiliation":[{"name":"Division of Cardiology Department of Internal Medicine Wonju Severance Christian Hospital Yonsei University Wonju College of Medicine Wonju Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2059-1584","authenticated-orcid":false,"given":"Sungsoo","family":"Cho","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine Department of Internal Medicine Dankook University HospitalDankook University College of Medicine Cheonan 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