{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T15:43:08Z","timestamp":1772552588300,"version":"3.50.1"},"reference-count":28,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"15","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2021,8,3]]},"abstract":"<jats:sec xml:lang=\"en\">\n            <jats:title>Background<\/jats:title>\n            <jats:p xml:lang=\"en\">There are limited contemporary data on the use of emergent coronary artery bypass grafting (CABG) in acute myocardial infarction.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Methods and Results<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              Adult (aged &gt;18\u00a0years) acute myocardial infarction admissions were identified using the National (Nationwide) Inpatient Sample (2000\u20132017) and classified by tertiles of admission year. Outcomes of interest included temporal trends of CABG use; age\u2010, sex\u2010, and race\u2010stratified trends in CABG use; in\u2010hospital mortality; hospitalization costs; and hospital length of stay. Of the 11\u00a0622\u00a0528 acute myocardial infarction admissions, emergent CABG was performed in 1\u00a0071\u00a0156 (9.2%). CABG utilization decreased overall (10.5% [2000] to 8.7% [2017]; adjusted odds ratio [OR], 0.98 [95% CI, 0.98\u20130.98];\n              <jats:italic>P<\/jats:italic>\n              &lt;0.001), in ST\u2010segment\u2013elevation myocardial infarction (10.2% [2000] to 5.2% [2017]; adjusted OR, 0.95 [95% CI, 0.95\u20130.95];\n              <jats:italic>P<\/jats:italic>\n              &lt;0.001) and non\u2013ST\u2010segment\u2013elevation myocardial infarction (10.8% [2000] to 10.0% [2017]; adjusted OR, 0.99 [95% CI, 0.99\u20130.99];\n              <jats:italic>P<\/jats:italic>\n              &lt;0.001), with consistent age, sex, and race trends. In 2012 to 2017, compared with 2000 to 2005, admissions receiving emergent CABG were more likely to have non\u2013ST\u2010segment\u2013elevation myocardial infarction (80.5% versus 56.1%), higher rates of noncardiac multiorgan failure (26.1% versus 8.4%), cardiogenic shock (11.5% versus 6.4%), and use of mechanical circulatory support (19.8% versus 18.7%). In\u2010hospital mortality in CABG admissions decreased from 5.3% (2000) to 3.6% (2017) (adjusted OR, 0.89; 95% CI, 0.88\u20130.89 [\n              <jats:italic>P<\/jats:italic>\n              &lt;0.001]) in the overall cohort, with similar temporal trends in patients with ST\u2010segment\u2013elevation myocardial infarction and non\u2013ST\u2010segment\u2013elevation myocardial infarction. An increase in lengths of hospital stay and hospitalization costs was seen over time.\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p xml:lang=\"en\">Utilization of CABG has decreased substantially in acute myocardial infarction admissions, especially in patients with ST\u2010segment\u2013elevation myocardial infarction. Despite an increase in acuity and multiorgan failure, in\u2010hospital mortality consistently decreased in this population.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/jaha.120.020517","type":"journal-article","created":{"date-parts":[[2021,5,15]],"date-time":"2021-05-15T14:00:11Z","timestamp":1621087211000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":24,"title":["Temporal Trends, Clinical Characteristics, and Outcomes of Emergent Coronary Artery Bypass Grafting for Acute Myocardial Infarction in the United States"],"prefix":"10.1161","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7952-0217","authenticated-orcid":false,"given":"Sri Harsha","family":"Patlolla","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Surgery Mayo Clinic Rochester MN"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ardaas","family":"Kanwar","sequence":"additional","affiliation":[{"name":"University of Minnesota Minneapolis MN"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9954-9711","authenticated-orcid":false,"given":"Wisit","family":"Cheungpasitporn","sequence":"additional","affiliation":[{"name":"Division of Nephrology and Hypertension Department of Medicine Mayo Clinic Rochester MN"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajkumar P.","family":"Doshi","sequence":"additional","affiliation":[{"name":"Department of Medicine University of Nevada Reno School of Medicine NV"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John M.","family":"Stulak","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery Mayo Clinic Rochester MN"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0037-0373","authenticated-orcid":false,"suffix":"Jr","given":"David R.","family":"Holmes","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Mayo Clinic Rochester MN"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Malcolm R.","family":"Bell","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Mayo Clinic Rochester MN"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mandeep","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Mayo Clinic Rochester MN"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1631-8238","authenticated-orcid":false,"given":"Saraschandra","family":"Vallabhajosyula","sequence":"additional","affiliation":[{"name":"Section of Interventional Cardiology Division of Cardiovascular Medicine Department of Medicine Emory University School of Medicine Atlanta GA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0b013e3182742c84"},{"key":"e_1_3_2_3_2","first-page":"1082","article-title":"2017 ESC guidelines for the management of acute myocardial infarction in patients presenting with ST\u2010segment elevation","volume":"70","author":"Ib\u00e1nez B","year":"2017","unstructured":"Ib\u00e1nez B, James S, Agewall S, Antunes MJ, Bucciarelli\u2010Ducci C, Bueno H, Caforio ALP, Crea F, Goudevenos JA, Halvorsen S, et al. 2017 ESC guidelines for the management of acute myocardial infarction in patients presenting with ST\u2010segment elevation. 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