{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T18:47:27Z","timestamp":1790275647056,"version":"4.1.0"},"reference-count":17,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"16","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2021,8,17]]},"abstract":"<jats:sec xml:lang=\"en\">\n            <jats:title>Background<\/jats:title>\n            <jats:p xml:lang=\"en\">Limited information is available regarding in\u2010hospital cardiac arrest (IHCA) in patients with COVID\u201019.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Methods and Results<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              We leveraged the American Heart Association COVID\u201019 Cardiovascular Disease (AHA COVID\u201019 CVD) Registry to conduct a cohort study of adults hospitalized for COVID\u201019. IHCA was defined as those with documentation of cardiac arrest requiring medication or electrical shock for resuscitation. Mixed effects models with random intercepts were used to identify independent predictors of IHCA and mortality while accounting for clustering at the hospital level. The study cohort included 8518 patients (6080 not in the intensive care unit [ICU]) with mean age of 61.5\u00a0years (SD 17.5). IHCA occurred in 509 (5.9%) patients overall with 375 (73.7%) in the ICU and 134 (26.3%) patients not in the ICU. The majority of patients at the time of ICHA were not in a shockable rhythm (76.5%). Independent predictors of IHCA included older age, Hispanic ethnicity (odds ratio [OR], 1.9; CI, 1.4\u20132.4;\n              <jats:italic>P<\/jats:italic>\n              &lt;0.001), and non\u2010Hispanic Black race (OR, 1.5; CI, 1.1\u20131.9;\n              <jats:italic>P<\/jats:italic>\n              =0.004). Other predictors included oxygen use on admission, quick Sequential Organ Failure Assessment score on admission, and hypertension. Overall, 35 (6.9%) patients with IHCA survived to discharge, with 9.1% for ICU and 0.7% for non\u2010ICU patients.\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p xml:lang=\"en\">Older age, Black race, and Hispanic ethnicity are independent predictors of IHCA in patients with COVID\u201019. Although the incidence is much lower than in ICU patients, approximately one\u2010quarter of IHCA events in patients with COVID\u201019 occur in non\u2010ICU settings, with the latter having a substantially lower survival to discharge rate.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/jaha.120.021204","type":"journal-article","created":{"date-parts":[[2021,8,11]],"date-time":"2021-08-11T08:59:08Z","timestamp":1628672348000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":27,"title":["Incidence, Predictors, and Outcomes of In\u2010Hospital Cardiac Arrest in COVID\u201019 Patients Admitted to Intensive and Non\u2010Intensive Care Units: Insights From the AHA COVID\u201019 CVD Registry"],"prefix":"10.1161","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6779-4106","authenticated-orcid":false,"given":"Prakash","family":"Acharya","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Medicine University of Kansas School of Medicine Kansas City KS"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sagar","family":"Ranka","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine University of Kansas School of Medicine Kansas City KS"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6685-5015","authenticated-orcid":false,"given":"Prince","family":"Sethi","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine University of Kansas School of Medicine Kansas City KS"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajani","family":"Bharati","sequence":"additional","affiliation":[{"name":"CUNY Graduate School of Public Health and Health Policy New York NY"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinxiang","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine University of Kansas School of Medicine Kansas City KS"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9947-3849","authenticated-orcid":false,"given":"Amit","family":"Noheria","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine University of Kansas School of Medicine Kansas City KS"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4331-6649","authenticated-orcid":false,"given":"Brahmajee K.","family":"Nallamothu","sequence":"additional","affiliation":[{"name":"Division of Cardiology Department of Medicine University of MichiganFrankel Cardiovascular Center Ann Arbor MI"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0180-349X","authenticated-orcid":false,"given":"Salim S.","family":"Hayek","sequence":"additional","affiliation":[{"name":"Division of Cardiology Department of Medicine University of MichiganFrankel Cardiovascular Center Ann Arbor MI"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2440-9033","authenticated-orcid":false,"given":"Kamal","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine University of Kansas School of Medicine Kansas City KS"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2020.04.005"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2020.07.011"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2020.4796"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.m3513"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0235653"},{"key":"e_1_3_1_7_2","unstructured":"Coronavirus Disease 2019 (COVID\u201019). CDC COVID Data Tracker. 2020. Available at: https:\/\/covid.cdc.gov\/covid\u2010data\u2010tracker\/#cases_totalcases. Accessed March 10 2020."},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMp2010758"},{"key":"e_1_3_1_9_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMp2006141"},{"key":"e_1_3_1_10_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCOUTCOMES.120.006967"},{"key":"e_1_3_1_11_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2016.20328"},{"key":"e_1_3_1_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.annemergmed.2016.10.007"},{"key":"e_1_3_1_13_2","volume-title":"R: A Language and Environment for Statistical Computing [Computer Program]","year":"2019","unstructured":"R: A Language and Environment for Statistical Computing [Computer Program]. Vienna, Austria: R foundation for Statistical Computing; 2019."},{"key":"e_1_3_1_14_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCOUTCOMES.120.006837"},{"key":"e_1_3_1_15_2","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.116.003638"},{"key":"e_1_3_1_16_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehaa500"},{"key":"e_1_3_1_17_2","unstructured":"Health disparities: race and hispanic origin. Provisional death counts for coronavirus disease 2019 (COVID\u201019). 2020. Available at: https:\/\/www.cdc.gov\/nchs\/nvss\/vsrr\/covid19\/health_disparities.htm. Accessed April 10 2020."},{"key":"e_1_3_1_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mayocp.2020.07.024"}],"container-title":["Journal of the American Heart Association"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/JAHA.120.021204","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T11:05:16Z","timestamp":1715598316000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/JAHA.120.021204"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,8,17]]},"references-count":17,"journal-issue":{"issue":"16","published-print":{"date-parts":[[2021,8,17]]}},"alternative-id":["10.1161\/JAHA.120.021204"],"URL":"https:\/\/doi.org\/10.1161\/jaha.120.021204","relation":{},"ISSN":["2047-9980"],"issn-type":[{"value":"2047-9980","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,8,17]]},"assertion":[{"value":"2021-02-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-06-28","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-08-11","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e021204"}}