{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T23:38:04Z","timestamp":1773877084459,"version":"3.50.1"},"reference-count":54,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"17","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2021,9,7]]},"abstract":"<jats:sec xml:lang=\"en\">\n            <jats:title>Background<\/jats:title>\n            <jats:p xml:lang=\"en\">Data are limited about young adults' characteristics and outcomes undergoing coronary artery bypass grafting (CABG).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Methods and Results<\/jats:title>\n            <jats:p xml:lang=\"en\">We used the National Inpatient Sample database to identify adults aged 18 to 45 years who underwent CABG between 2004 and 2018. The data were weighted to generate national estimates of the entire US hospitalized population. We identified 110\u00a0463 CABG cases, equivalent to 62.2 per 1\u00a0000\u00a0000 person\u2010years; 27.1% were women, and 70.2% were White adults. Overall, annual CABG volume per 1\u00a0000\u00a0000 significantly decreased from 87.3 in 2004 to 45.7 in 2018. The prevalence of obesity, diabetes mellitus, hypertension, drug abuse, and chronic medical conditions increased over time. Overall, inpatient mortality was 1.76%; ST\u2010segment\u2013elevation myocardial infarction, non\u2013ST\u2010segment\u2013elevation myocardial infarction, heart failure, peripheral vascular disease, renal failure, and valvular surgery were associated with higher inpatient mortality. Women had higher inpatient mortality than men (2.29% versus 1.57%), and Black patients had higher deaths than White patients (2.86% versus 1.58%). Inpatient mortality remained stable overall, according to sex, race, or clinical indication of CABG. However, the mean length of stay (8.4\u00a0days in 2004 to 9.5\u00a0days in 2018) and inflation\u2010adjusted cost of care ($40\u00a0522.8 in 2004 to $52\u00a0434.2 in 2018) significantly increased during the study period.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p xml:lang=\"en\">Despite the increased burden of cardiometabolic risk factors, the inpatient mortality in young adults undergoing CABG remained stable during the last 15\u00a0years. However, CABG volumes have decreased, but length of stay and inflation\u2010adjusted costs have increased over time.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/jaha.121.021361","type":"journal-article","created":{"date-parts":[[2021,8,28]],"date-time":"2021-08-28T09:14:46Z","timestamp":1630142086000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":21,"title":["Trends in Characteristics and Outcomes of Hospitalized Young Patients Undergoing Coronary Artery Bypass Grafting in the United States, 2004 to 2018"],"prefix":"10.1161","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3434-6136","authenticated-orcid":false,"given":"Sourbha S.","family":"Dani","sequence":"first","affiliation":[{"name":"Division of Cardiology Lahey Hospital and Medical CenterBeth Israel Lahey Health Burlington MA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdul Mannan Khan","family":"Minhas","sequence":"additional","affiliation":[{"name":"Department of Medicine Forrest General Hospital Hattiesburg MS"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adeel","family":"Arshad","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology Ohio State University Comprehensive Cancer Care Center Columbus OH"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Troy","family":"Krupica","sequence":"additional","affiliation":[{"name":"Department of Medicine West Virginia University Morgantown WV"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6041-3876","authenticated-orcid":false,"given":"Sachin S.","family":"Goel","sequence":"additional","affiliation":[{"name":"Department of Cardiology Houston Methodist DeBakey Heart &amp; Vascular Center Houston TX"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9541-6954","authenticated-orcid":false,"given":"Salim S.","family":"Virani","sequence":"additional","affiliation":[{"name":"Michael E. 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