{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T23:19:03Z","timestamp":1782775143130,"version":"3.54.5"},"reference-count":40,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2022,1,18]]},"abstract":"<jats:sec xml:lang=\"en\">\n            <jats:title>Background<\/jats:title>\n            <jats:p xml:lang=\"en\">Women with a history of obstetric complications are at increased risk of cardiovascular disease, but whether they should be specifically targeted for cardiovascular disease (CVD) risk screening is unknown.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Methods and Results<\/jats:title>\n            <jats:p xml:lang=\"en\">We used linked data from the Norwegian HUNT (Tr\u00f8ndelag Health) Study and the Medical Birth Registry of Norway to create a population\u2010based, prospective cohort of parous women. Using an established CVD risk prediction model (A Norwegian risk model for cardiovascular disease), we predicted 10\u2010year risk of CVD (nonfatal myocardial infarction, fatal coronary heart disease, and nonfatal or fatal stroke) based on established risk factors (age, systolic blood pressure, total and high\u2010density lipoprotein cholesterol, smoking, antihypertensive use, and family history of myocardial infarction). Predicted 10\u2010year CVD risk scores in women aged between 40 and 60\u00a0years were consistently higher in those with a history of obstetric complications. For example, when aged 40\u00a0years, women with a history of preeclampsia had a 0.06 percentage point higher mean risk score than women with all normotensive deliveries, and when aged 60\u00a0years this difference was 0.86. However, the differences in the proportion of women crossing established clinical thresholds for counseling and treatment in women with and without a complication were modest.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p xml:lang=\"en\">Findings do not support targeting parous women with a history of pregnancy complications for CVD screening. However, pregnancy complications identify women who would benefit from primordial and primary prevention efforts such as encouraging and supporting behavioral changes to reduce CVD risk in later life.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/jaha.121.021733","type":"journal-article","created":{"date-parts":[[2022,1,11]],"date-time":"2022-01-11T13:59:07Z","timestamp":1641909547000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":11,"title":["Ten\u2010Year Cardiovascular Disease Risk Trajectories by Obstetric History: A Longitudinal Study in the Norwegian HUNT Study"],"prefix":"10.1161","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7741-9470","authenticated-orcid":false,"given":"Abigail","family":"Fraser","sequence":"first","affiliation":[{"name":"Population Health Sciences Bristol Medical School University of Bristol Bristol UK"},{"name":"Medical Research Council Integrative Epidemiology Unit at the University of Bristol Bristol UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0376-4375","authenticated-orcid":false,"given":"Amanda R.","family":"Markovitz","sequence":"additional","affiliation":[{"name":"Department of Epidemiology Harvard T.H. Chan School of Public Health Boston MA"},{"name":"Division of Women\u2019s Health Brigham and Women\u2019s Hospital Boston MA"},{"name":"Connors Center for Women\u2019s Health and Gender BiologyBrigham and Women\u2019s Hospital Boston MA"},{"name":"Mathematica Cambridge MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eirin B.","family":"Haug","sequence":"additional","affiliation":[{"name":"Population Health Sciences Bristol Medical School University of Bristol Bristol UK"},{"name":"Medical Research Council Integrative Epidemiology Unit at the University of Bristol Bristol UK"},{"name":"K.G. Jebsen Center for Genetic Epidemiology Department of Public Health and Nursing NTNUNorwegian University of Science and Technology Trondheim Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1344-9707","authenticated-orcid":false,"given":"Julie","family":"Horn","sequence":"additional","affiliation":[{"name":"HUNT Research Center Department of Public Health and Nursing NTNUNorwegian University of Science and Technology Levanger Norway"},{"name":"Department of Obstetrics and Gynecology Levanger HospitalNord\u2010Tr\u00f8ndelag Hospital Trust Levanger Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2061-4336","authenticated-orcid":false,"given":"P\u00e5l Richard","family":"Romundstad","sequence":"additional","affiliation":[{"name":"Department of Public Health and Nursing NTNUNorwegian University of Science and Technology Trondheim Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H\u00e5vard","family":"Dalen","sequence":"additional","affiliation":[{"name":"Department of Medicine Levanger HospitalNord\u2010Tr\u00f8ndelag Hospital Trust Levanger Norway"},{"name":"Department of Circulation and Medical Imaging NTNUNorwegian University of Science and Technology Trondheim Norway"},{"name":"Cardiac Clinic St Olavs HospitalTrondheim University Hospital Trondheim Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5066-8808","authenticated-orcid":false,"given":"Janet","family":"Rich\u2010Edwards","sequence":"additional","affiliation":[{"name":"Department of Epidemiology Harvard T.H. Chan School of Public Health Boston MA"},{"name":"Division of Women\u2019s Health Brigham and Women\u2019s Hospital Boston MA"},{"name":"Connors Center for Women\u2019s Health and Gender BiologyBrigham and Women\u2019s Hospital Boston MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3837-2101","authenticated-orcid":false,"given":"Bj\u00f8rn Olav","family":"\u00c5svold","sequence":"additional","affiliation":[{"name":"K.G. 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