{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:55:03Z","timestamp":1787018103298,"version":"build-2736575974"},"reference-count":24,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"18","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2021,9,21]]},"abstract":"<jats:sec xml:lang=\"en\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p xml:lang=\"en\">It is well established that postoperative atrial fibrillation (POAF) is associated with adverse postoperative outcomes after major cardiac operations. The purpose of this study was to investigate the incidence of new\u2010onset POAF after successful total arch repair surgery and the association between POAF and in\u2010hospital mortality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Methods and Results<\/jats:title>\n                    <jats:p xml:lang=\"en\">\n                      All consecutive patients undergoing total arch repair from September 2012 to December 2019 in Fuwai hospital were enrolled (n=1280). Patients diagnosed with preoperative atrial fibrillation were excluded. POAF was diagnosed as the new\u2010onset atrial fibrillation or flutter for more than 5\u00a0minutes based on continuous electrocardiogram monitoring. A logistic regression model was used to determine predictors of in\u2010hospital mortality. Multivariable adjustment, inverse probability of treatment weighting, and propensity score matching were used to adjust for confounders. POAF was diagnosed in 32.3% (411\/1271) of this cohort population. The occurrence of new\u2010onset POAF was associated with age (odds ratio [OR], 1.05; 95% CI, 1.04\u20131.06;\n                      <jats:italic>P<\/jats:italic>\n                      &lt;0.001), male sex (OR, 0.72; 95% CI, 0.52\u20130.98;\n                      <jats:italic>P<\/jats:italic>\n                      =0.035), and surgery duration (OR, 1.2; 95% CI, 1.12\u20131.28;\n                      <jats:italic>P<\/jats:italic>\n                      &lt;0.001). The in\u2010hospital mortality was significantly higher in patients with POAF than those without POAF (10.7% versus 2.4%,\n                      <jats:italic>P<\/jats:italic>\n                      &lt;0.001). Inverse probability of treatment weighting and propensity score matching analyses confirmed the results. The increased in\u2010hospital mortality in POAF group still existed among subgroup analysis based on different age, sex, hypertension, smoking, and hypokalemia, combined with cardiac surgery, and deep hypothermic circulatory arrest.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p xml:lang=\"en\">More careful attention should be given to POAF after total arch repair surgery. The incidence of POAF after total arch repair surgery was 32.3% and associated with increased in\u2010hospital mortality. The elderly female patient who experienced longer operation duration was at highest risk for POAF.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/jaha.121.021980","type":"journal-article","created":{"date-parts":[[2021,9,17]],"date-time":"2021-09-17T06:22:04Z","timestamp":1631859724000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":16,"title":["New\u2010Onset Postoperative Atrial Fibrillation After Total Arch Repair Is Associated With Increased In\u2010Hospital Mortality"],"prefix":"10.1161","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5793-7951","authenticated-orcid":false,"given":"Rui","family":"Zhao","sequence":"first","affiliation":[{"name":"Department of Vascular Surgery Fuwai HospitalState Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular DiseasesChinese Academy of Medical Sciences and Peking Union Medical College Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhao","family":"Wang","sequence":"additional","affiliation":[{"name":"Cardiac Arrhythmia Center Fuwai HospitalState Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular DiseasesChinese Academy of Medical Sciences and Peking Union Medical College Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fangfang","family":"Cao","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery Fuwai HospitalState Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular DiseasesChinese Academy of Medical Sciences and Peking Union Medical College Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery Fuwai HospitalState Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular DiseasesChinese Academy 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Arrhythmia Center Fuwai HospitalState Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular DiseasesChinese Academy of Medical Sciences and Peking Union Medical College Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7874-9052","authenticated-orcid":false,"given":"Cuntao","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery Fuwai HospitalState Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular DiseasesChinese Academy of Medical Sciences and Peking Union Medical College Beijing 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