{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T18:32:19Z","timestamp":1784140339703,"version":"3.55.0"},"reference-count":53,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"8","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2022,4,19]]},"abstract":"<jats:sec xml:lang=\"en\">\n            <jats:title>Background<\/jats:title>\n            <jats:p xml:lang=\"en\">The effectiveness of a nurse\u2010led in\u2010hospital monitoring protocol with mobile ECG (iECG) was investigated for detecting atrial fibrillation in patients post\u2010ischemic stroke or post\u2010transient ischemic attack. The study aimed to assess the cost\u2010effectiveness of using iECG during the initial hospital stay compared with standard 24\u2010hour Holter monitoring.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Methods and Results<\/jats:title>\n            <jats:p xml:lang=\"en\">A Markov microsimulation model was constructed to simulate the lifetime health outcomes and costs. The rate of atrial fibrillation detection in iECG and Holter monitoring during the in\u2010hospital phase and characteristics of modeled population (ie, age, sex, CHA2DS2\u2010VASc) were informed by patient\u2010level data. Costs related to recurrent stroke, stroke management, medications (new oral anticoagulants), and rehabilitation were included. The cost\u2010effectiveness analysis outcome was calculated as an incremental cost per quality\u2010adjusted life\u2010year gained. As results, monitoring patients with iECG post\u2010stroke during the index hospitalization was associated with marginally higher costs (A$31\u00a0196) and greater benefits (6.70 quality\u2010adjusted life\u2010years) compared with 24\u2010hour Holter surveillance (A$31\u00a0095 and 6.66 quality\u2010adjusted life\u2010years) over a 20\u2010year time horizon, with an incremental cost\u2010effectiveness ratio of $3013\/ quality\u2010adjusted life\u2010years. Monitoring patients with iECG also contributed to lower recurrence of stroke and stroke\u2010related deaths (140 recurrent strokes and 20 deaths avoided per 10\u00a0000 patients). The probabilistic sensitivity analyses suggested iECG is highly likely to be a cost\u2010effective intervention (100% probability).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p xml:lang=\"en\">A nurse\u2010led iECG monitoring protocol during the acute hospital stay was found to improve the rate of atrial fibrillation detection and contributed to slightly increased costs and improved health outcomes. Using iECG to monitor patients post\u2010stroke during initial hospitalization is recommended to complement routine care.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/jaha.121.022735","type":"journal-article","created":{"date-parts":[[2022,4,12]],"date-time":"2022-04-12T09:48:54Z","timestamp":1649756934000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":9,"title":["Cost\u2010Effectiveness of Monitoring Patients Post\u2010Stroke With Mobile ECG During the Hospital Stay"],"prefix":"10.1161","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9734-1140","authenticated-orcid":false,"given":"Lan","family":"Gao","sequence":"first","affiliation":[{"name":"Faculty of Health Deakin Health Economics Institute for Health TransformationDeakin University Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6890-5250","authenticated-orcid":false,"given":"Marj","family":"Moodie","sequence":"additional","affiliation":[{"name":"Faculty of Health Deakin Health Economics Institute for Health TransformationDeakin University Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3809-2911","authenticated-orcid":false,"given":"Ben","family":"Freedman","sequence":"additional","affiliation":[{"name":"Heart Research Institute Charles Perkins Centre, and Concord Hospital CardiologyUniversity of Sydney Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina","family":"Lam","sequence":"additional","affiliation":[{"name":"The Melbourne Brain Centre at the Royal Melbourne Hospital and the University of Melbourne Parkville Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans","family":"Tu","sequence":"additional","affiliation":[{"name":"Department of Neurology and Medicine Western HealthThe University of Melbourne Footscray Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Corey","family":"Swift","sequence":"additional","affiliation":[{"name":"The Melbourne Brain Centre at the Royal Melbourne Hospital and the University of Melbourne Parkville Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0609-758X","authenticated-orcid":false,"given":"Sze\u2010Ho","family":"Ma","sequence":"additional","affiliation":[{"name":"Division of Neurology Department of Medicine and Therapeutics Gerald Choa Neuroscience Centre Lui Che Woo Institute of Innovative Medicine Faculty of Medicine Prince of Wales HospitalThe Chinese University of Hong Kong Hong Kong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent C. 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