{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T12:36:41Z","timestamp":1792154201935,"version":"4.4.0"},"reference-count":40,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2022,1,18]]},"abstract":"<jats:sec xml:lang=\"en\">\n            <jats:title>Background<\/jats:title>\n            <jats:p xml:lang=\"en\">Although pregnancy\u2010induced hypertension (PIH) is associated with an elevated cardiovascular risk, long\u2010term studies or prepregnancy baseline data are scarce. Therefore, using a large nationwide cohort with prepregnancy periodic health screening data, we investigated whether clinically significant arrhythmia incidence increases after PIH.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Methods and Results<\/jats:title>\n            <jats:p xml:lang=\"en\">Data were extracted from the Korea National Health Insurance database and combined with the National Health Screening Examination database; women who gave birth between 2007 and 2015 and underwent the national health screening test within a year before pregnancy were followed up until 2016. We excluded women who had a diagnosis of arrhythmia within 1\u00a0year before pregnancy. The primary outcome was significant arrhythmia during the year after delivery. Secondary analysis included only specific diagnostic codes of arrhythmia with clinical significance. Additionally, the risk of arrhythmia was stratified by the use of magnesium sulfate. Of 2\u00a0035\u00a0684 women (PIH; n=37\u00a0297 versus normotensive pregnancy; n=1\u00a0998\u00a0387), the PIH group had a higher prepregnancy risk profile and showed a higher incidence of arrhythmia than women with normotensive pregnancies within 1\u00a0year. Women with PIH had a significantly higher risk of atrial flutter\/fibrillation and atrioventricular block, but not lethal arrhythmias. Other predictors of arrhythmia development included advanced maternal age and cesarean section. Stratified analysis showed a higher risk of arrhythmia with magnesium sulfate use.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p xml:lang=\"en\">PIH was significantly associated with the development of arrhythmia within 1\u00a0year after delivery. Nevertheless, the incidence of lethal arrhythmias was not increased by PIH. Arrhythmia, especially atrial fibrillation, may largely contribute to increasing the future cardiovascular risk in women with a PIH history.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/jaha.121.023013","type":"journal-article","created":{"date-parts":[[2022,1,11]],"date-time":"2022-01-11T14:00:55Z","timestamp":1641909655000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":12,"title":["Increased Cardiac Arrhythmia After Pregnancy\u2010Induced Hypertension: A South Korean Nationwide Database Study"],"prefix":"10.1161","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2571-7898","authenticated-orcid":false,"given":"Yoonjee","family":"Park","sequence":"first","affiliation":[{"name":"Division of Cardiology Department of Internal Medicine Heart Vascular Stroke InstituteSamsung Medical CenterSungkyunkwan University School of Medicine Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6761-0944","authenticated-orcid":false,"given":"Geum Joon","family":"Cho","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Korea University College of Medicine Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0854-9079","authenticated-orcid":false,"given":"Seung\u2010Young","family":"Roh","sequence":"additional","affiliation":[{"name":"Division of Cardiology Department of Internal Medicine Korea University Guro Hospital Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5096-4428","authenticated-orcid":false,"given":"Jin Oh","family":"Na","sequence":"additional","affiliation":[{"name":"Division of Cardiology Department of Internal Medicine Korea University Guro Hospital Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min\u2010Jeong","family":"Oh","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Korea University College of Medicine Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_2_2_2","first-page":"1122","article-title":"Report of the American College of Obstetricians and Gynecologists\u2019 task force on hypertension in pregnancy","volume":"122","author":"Hypertension in pregnancy","year":"2013","unstructured":"Hypertension in pregnancy . 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