{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T19:19:15Z","timestamp":1789154355698,"version":"build-2803163510"},"reference-count":29,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"20","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2022,10,18]]},"abstract":"<jats:sec sec-type=\"background\" xml:lang=\"en\">\n            <jats:title>Background<\/jats:title>\n            <jats:p xml:lang=\"en\">Malnutrition is associated with poor prognosis in several cardiovascular diseases. However, its prognostic impact in patients undergoing transcatheter edge\u2010to\u2010edge mitral valve repair (TEER) is not well known. This study sought to assess the prevalence, clinical associations, and prognostic consequences of malnutrition in patients undergoing TEER.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Methods and Results<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              A total of 892 patients undergoing TEER from the international MIVNUT (Mitral Valve Repair and Nutritional Status) registry were studied. Malnutrition status was assessed with the Controlling Nutritional Status score. The association of nutritional status with mortality was analyzed with multivariable Cox regression models, whereas the association with heart failure admission was assessed by Fine\u2010Gray models, with death as a competing risk. According to the Controlling Nutritional Status score, 74.4% of patients with TEER had any degree of malnutrition at the time of TEER (75.1% in patients with body mass index &lt;25\u2009kg\/m\n              <jats:sup>2<\/jats:sup>\n              , 72.1% in those with body mass index \u226525\u2009kg\/m\n              <jats:sup>2<\/jats:sup>\n              ). However, only 20% had moderate\u2013severe malnutrition. TEER was successful in most of patients (94.2%). During a median follow\u2010up of 1.6\u2009years (interquartile range, 0.6\u20133.0), 267 (29.9%) patients died and 256 patients (28.7%) were admitted for heart failure after TEER. Compared with normal nutritional status moderate\u2013severe malnutrition resulted a strong predictor of mortality (adjusted hazard ratio [HR], 2.1 [95% CI, 1.1\u20132.4];\n              <jats:italic>P<\/jats:italic>\n              &lt;0.001) and heart failure admission (adjusted subdistribution HR, 1.6 [95% CI, 1.1\u20132.4];\n              <jats:italic>P<\/jats:italic>\n              =0.015).\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p xml:lang=\"en\">Malnutrition is common among patients submitted to TEER, and moderate\u2013severe malnutrition is strongly associated with increased mortality and heart failure readmission. Assessment of nutritional status in these patients may help to improve risk stratification.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/jaha.121.023121","type":"journal-article","created":{"date-parts":[[2022,10,11]],"date-time":"2022-10-11T00:54:26Z","timestamp":1665449666000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":17,"title":["Prognostic Impact of Nutritional Status After Transcatheter Edge\u2010to\u2010Edge Mitral Valve Repair: The MIVNUT Registry"],"prefix":"10.1161","volume":"11","author":[{"given":"Berenice","family":"Caneiro\u2010Queija","sequence":"first","affiliation":[{"name":"Hospital \u00c1lvaro Cunqueiro and Instituto de Investigaci\u00f3n Sanitaria Galicia Sur Vigo 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