{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,8]],"date-time":"2025-11-08T17:59:24Z","timestamp":1762624764885,"version":"3.41.2"},"reference-count":39,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2022,3,15]]},"abstract":"<jats:sec xml:lang=\"en\">\n            <jats:title>Background<\/jats:title>\n            <jats:p xml:lang=\"en\">We investigated the early postoperative effect of percutaneous transluminal renal angioplasty on ambulatory blood pressure (BP) and the circadian characteristics of natriuresis and autonomic nerve activity.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Methods and Results<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              A total of 64 patients with hypertension with hemodynamically significant renal artery stenosis (mean age, 60.0\u00b121.0\u00a0years; 31.3% fibromuscular dysplasia) who underwent angioplasty were included, and circadian characteristics of natriuresis as well as heart rate variability indices, including 24\u2010hour BP, low\u2010frequency and high\u2010frequency (HF) components, and the percentage of differences between adjacent normal R\u2010R intervals &gt;50\u00a0ms were evaluated using an oscillometric device, TM\u20102425, both at baseline and 3\u00a0days after angioplasty. In both the fibromuscular dysplasia and atherosclerotic stenosis groups, 24\u2010hour systolic BP (fibromuscular dysplasia, \u221219\u00b114; atherosclerotic renal artery stenosis, \u221211\u00b19\u00a0mm\u00a0Hg), percentage of differences between adjacent normal R\u2010R intervals &gt;50 ms, HF, brain natriuretic peptide, and nighttime urinary sodium excretion decreased (all\n              <jats:italic>P<\/jats:italic>\n              &lt;0.01), and heart rate increased (both\n              <jats:italic>P<\/jats:italic>\n              &lt;0.05) after angioplasty. In both groups, revascularization increased the night\/day ratios of percentage of differences between adjacent normal R\u2010R intervals &gt;50 ms (both\n              <jats:italic>P<\/jats:italic>\n              &lt;0.01) and HF, and decreased those of low frequency\/HF (all\n              <jats:italic>P<\/jats:italic>\n              &lt;0.05) and nighttime urinary sodium excretion (fibromuscular dysplasia, 1.17\u00b10.15 to 0.78\u00b10.09; atherosclerotic renal artery stenosis, 1.37\u00b10.10 to 0.99\u00b10.06, both\n              <jats:italic>P<\/jats:italic>\n              &lt;0.01). Multiple logistic regression analysis indicated that a 1\u2010SD increase in baseline low frequency\/HF was associated with at least a 15% decrease in 24\u2010hour systolic BP after angioplasty (odds ratio, 2.30 [95% CI, 1.03\u20135.67];\n              <jats:italic>P<\/jats:italic>\n              &lt;0.05).\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p xml:lang=\"en\">Successful revascularization results in a significant BP decrease in the early postoperative period. Intrarenal perfusion might be a key modulator of the circadian patterns of autonomic nerve activity and natriuresis, and pretreatment heart rate variability evaluation seems to be important for treatment success.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/jaha.121.023655","type":"journal-article","created":{"date-parts":[[2022,3,9]],"date-time":"2022-03-09T10:05:21Z","timestamp":1646820321000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Impact of Percutaneous Transluminal Renal Angioplasty on Autonomic Nervous System and Natriuresis in Hypertensive Patients With Renal Artery Stenosis"],"prefix":"10.1161","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1932-7324","authenticated-orcid":false,"given":"Yoshio","family":"Iwashima","sequence":"first","affiliation":[{"name":"Department of Nephrology and Hypertension Dokkyo Medical University Tochigi Japan"},{"name":"Division of Hypertension and Nephrology National Cerebral and Cardiovascular Center Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Kusunoki","sequence":"additional","affiliation":[{"name":"Division of Hypertension and Nephrology National Cerebral and Cardiovascular Center Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akira","family":"Taniyama","sequence":"additional","affiliation":[{"name":"Division of Hypertension and Nephrology National Cerebral and Cardiovascular Center Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeshi","family":"Horio","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Ishikiriseiki Hospital Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shin\u2010ichiro","family":"Hayashi","sequence":"additional","affiliation":[{"name":"Division of Hypertension and Nephrology National Cerebral and Cardiovascular Center Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1917-8867","authenticated-orcid":false,"given":"Masatsugu","family":"Kishida","sequence":"additional","affiliation":[{"name":"Division of Hypertension and Nephrology National Cerebral and Cardiovascular Center Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tetsuya","family":"Fukuda","sequence":"additional","affiliation":[{"name":"Department of Radiology National Cerebral and Cardiovascular Center Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9394-4315","authenticated-orcid":false,"given":"Fumiki","family":"Yoshihara","sequence":"additional","affiliation":[{"name":"Division of Hypertension and Nephrology National Cerebral and Cardiovascular Center Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshihiko","family":"Ishimitsu","sequence":"additional","affiliation":[{"name":"Department of Nephrology and Hypertension Dokkyo Medical University Tochigi Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0049-259X","authenticated-orcid":false,"given":"Yuhei","family":"Kawano","sequence":"additional","affiliation":[{"name":"Division of Hypertension and Nephrology National Cerebral and Cardiovascular Center Osaka Japan"},{"name":"Department of Medical Technology Teikyo University Fukuoka Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0905368"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-150-12-200906160-00119"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1310753"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.7326\/M16-1053"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.2174\/15734021113099990007"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.99.19.2537"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/00004872-200206000-00031"},{"key":"e_1_3_1_9_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.hyp.17.6.1057"},{"key":"e_1_3_1_10_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199702133360702"},{"key":"e_1_3_1_11_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.93.5.1043"},{"key":"e_1_3_1_12_2","doi-asserted-by":"publisher","DOI":"10.1097\/HJH.0000000000000928"},{"key":"e_1_3_1_13_2","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.112.196717"},{"key":"e_1_3_1_14_2","first-page":"1292","article-title":"Association of renal resistive index with target organ damage in essential hypertension","volume":"25","author":"Doi Y","year":"2012","unstructured":"Doi Y, Iwashima Y, Yoshihara F, Kamide K, Takata H, Fujii T, Kubota Y, Nakamura S, Horio T, Kawano Y. 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