{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:55:04Z","timestamp":1787018104364,"version":"build-2736575974"},"reference-count":17,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2022,2]]},"abstract":"<jats:sec xml:lang=\"en\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p xml:lang=\"en\">Patients resuscitated from out\u2010of\u2010hospital circulatory arrest (OHCA) frequently have cardiopulmonary resuscitation injuries identifiable by computed tomography, although the prevalence, types of injury, and effects on clinical outcomes are poorly characterized.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Methods and Results<\/jats:title>\n                    <jats:p xml:lang=\"en\">\n                      We assessed the prevalence of resuscitation\u2010associated injuries in a prospective, observational study of a head\u2010to\u2010pelvis sudden\u2010death computed tomography scan within 6\u00a0hours of successful OHCA resuscitation. Primary outcomes included total injuries and time\u2010critical injuries (such as organ laceration). Exploratory outcomes were injury associations with mechanical cardiopulmonary resuscitation and survival to discharge. Among 104 patients with OHCA (age 56\u00b115\u00a0years, 30% women), 58% had bystander cardiopulmonary resuscitation, and total cardiopulmonary resuscitation time was 15\u00b111\u00a0minutes. The prevalence of resuscitation\u2010associated injury was high (81%), including 15 patients (14%) with time\u2010critical findings. Patients with resuscitation injury were older (58\u00b115 versus 46\u00b113\u00a0years;\n                      <jats:italic>P<\/jats:italic>\n                      &lt;0.001), but had otherwise similar baseline characteristics and survival compared with those without. Mechanical chest compression systems (27%) had more frequent sternal fractures (36% versus 12%;\n                      <jats:italic>P<\/jats:italic>\n                      =0.009), including displaced fractures (18% versus 1%;\n                      <jats:italic>P<\/jats:italic>\n                      =0.005), but no difference in survival (46% versus 41%;\n                      <jats:italic>P<\/jats:italic>\n                      =0.66).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p xml:lang=\"en\">In patients resuscitated from OHCA, head\u2010to\u2010pelvis sudden\u2010death computed tomography identified resuscitation injuries in most patients, with nearly 1 in 7 with time\u2010critical complications, and one\u2010half with extensive rib\u2010cage injuries. These data suggest that sudden\u2010death computed tomography may have additional diagnostic utility and treatment implications beyond evaluating causes of OHCA. These important findings need to also be taken in context of the certain fatal outcome without resuscitation efforts.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Registration<\/jats:title>\n                    <jats:p xml:lang=\"en\">\n                      URL:\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/www.clinicaltrials.gov\">https:\/\/www.clinicaltrials.gov<\/jats:ext-link>\n                      ; Unique identifier: NCT03111043.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/jaha.121.023949","type":"journal-article","created":{"date-parts":[[2022,1,19]],"date-time":"2022-01-19T05:36:13Z","timestamp":1642570573000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":36,"title":["Prevalence and Patterns of Resuscitation\u2010Associated Injury Detected by Head\u2010to\u2010Pelvis Computed Tomography After Successful Out\u2010of\u2010Hospital Cardiac Arrest Resuscitation"],"prefix":"10.1161","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5468-3941","authenticated-orcid":false,"given":"Aris","family":"Karatasakis","sequence":"first","affiliation":[{"name":"Division of Cardiology University of Washington Seattle WA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8230-7265","authenticated-orcid":false,"given":"Basar","family":"Sarikaya","sequence":"additional","affiliation":[{"name":"Department of Radiology University of Washington Seattle WA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda","family":"Liu","sequence":"additional","affiliation":[{"name":"Division of Cardiology University of Washington Seattle WA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9879-8660","authenticated-orcid":false,"given":"Martin L.","family":"Gunn","sequence":"additional","affiliation":[{"name":"Department of Radiology University of Washington Seattle WA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1855-1102","authenticated-orcid":false,"given":"Peter J.","family":"Kudenchuk","sequence":"additional","affiliation":[{"name":"Division of Cardiology University of Washington Seattle WA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Medley O.","family":"Gatewood","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine University of Washington Seattle WA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1644-7814","authenticated-orcid":false,"given":"Charles","family":"Maynard","sequence":"additional","affiliation":[{"name":"Department of Health Services School of Public Health and Community Medicine University of Washington Seattle WA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0322-3181","authenticated-orcid":false,"given":"Michael R.","family":"Sayre","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine University of Washington Seattle WA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7152-8887","authenticated-orcid":false,"given":"Catherine R.","family":"Counts","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine University of Washington Seattle WA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David J.","family":"Carlbom","sequence":"additional","affiliation":[{"name":"Division of Pulmonary Critical Care, and Sleep Medicine University of Washington Seattle WA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7330-0782","authenticated-orcid":false,"given":"Rachael M.","family":"Edwards","sequence":"additional","affiliation":[{"name":"Department of Radiology University of Washington Seattle WA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2362-6498","authenticated-orcid":false,"given":"Kelley R. H.","family":"Branch","sequence":"additional","affiliation":[{"name":"Division of Cardiology University of Washington Seattle WA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000950"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000916"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.92.2.287"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/acem.14228"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2020.04.033"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.4271\/2006-01-0250"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbi.2019.103208"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbi.2008.08.010"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2003.10.003"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-008-1255-9"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2021.02.012"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2020.09.012"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2014.12.022"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2015.11.004"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0300-9572(99)00033-7"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0300-9572(99)00137-9"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1097\/TA.0000000000000086"}],"container-title":["Journal of the American Heart Association"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/JAHA.121.023949","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T07:44:26Z","timestamp":1715586266000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/JAHA.121.023949"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2]]},"references-count":17,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022,2]]}},"alternative-id":["10.1161\/JAHA.121.023949"],"URL":"https:\/\/doi.org\/10.1161\/jaha.121.023949","relation":{},"ISSN":["2047-9980"],"issn-type":[{"value":"2047-9980","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,2]]},"assertion":[{"value":"2021-09-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-12-08","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-01-19","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e023949"}}