{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T14:23:17Z","timestamp":1760710997062,"version":"3.41.2"},"reference-count":23,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"15","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2022,8,2]]},"abstract":"<jats:sec sec-type=\"background\" xml:lang=\"en\">\n            <jats:title>Background<\/jats:title>\n            <jats:p xml:lang=\"en\">Despite the known significant morbidity and mortality associated with cardiovascular disease and peripheral vascular disease (PVD), contemporary data describing racial demographics in PVD mortality are scarce.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Methods and Results<\/jats:title>\n            <jats:p xml:lang=\"en\">Using the multiple causes of death file from the Centers for Disease Control and Prevention\u2019s Wide\u2010Ranging Online Data for Epidemiologic Research, we analyzed the trends of age\u2010adjusted mortality (AAMR) for PVD and its subtypes (aortic aneurysm\/dissection, arterial thrombosis, venous thrombosis\/disease, pulmonary embolism), by race and sex between 1999 and 2019. Of the 17\u2009826\u2009871 deaths attributed to cardiovascular disease, a total of 888\u2009187 (5.0%) PVD deaths were analyzed during the study period (12.4% Black, 85.6% White). Between 1999 and 2019, AAMR for PVD decreased by 52% (24.8\u201311.8 per 100\u2009000 people) in the overall population. Despite a decrease in the overall mortality across all race and sex groups, Black men and Black women continued to have higher mortality for PVD (1.5\u00d7), aortic dissection (1.8\u00d7), arterial thrombosis (1.3\u00d7), and venous thrombosis\/disease (2.0\u00d7) mortality compared with White men and White women in 2019. While there was a 53% decrease in PVD among White individuals (AAMR 24.5\u201311.5 per 100\u2009000), there was only a 43% decrease (30.0\u201317.1) in PVD AAMR in Black individuals between 1999 and 2019. The ratio of PVD AAMR increased from 1.2 (1999) to 1.5 (2019) in Black men\/White men and from to 1.3 (1999) to 1.5 (2019) in Black women\/White women. Similar trends were noted in aortic dissection (Black men\/White men, 1.2\u20131.8; and Black women\/White women, 1.5\u20131.7), arterial thrombosis (Black men\/White men, 1.0\u20131.3; and Black women\/White women, 0.9\u20131.3), and venous thrombosis\/disease (Black men\/White men, 1.7\u20131.8; and Black women\/White women, 1.7\u20132.0).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p xml:lang=\"en\">In this retrospective review of death certificate data in the United States, we demonstrate continued significant disparities between Black and White populations in PVD mortality and its subtypes. Future studies should investigate etiologies and social determinants of PVD mortality.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/jaha.121.025276","type":"journal-article","created":{"date-parts":[[2022,7,19]],"date-time":"2022-07-19T09:01:52Z","timestamp":1658221312000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":13,"title":["Proportionate and Absolute Vascular Disease Mortality by Race and Sex in the United States From 1999 to 2019"],"prefix":"10.1161","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0635-6131","authenticated-orcid":false,"given":"Scott E.","family":"Janus","sequence":"first","affiliation":[{"name":"Department of Medicine University Hospitals Cleveland OH"},{"name":"Harrington Heart and Vascular Institute University Hospitals and School of Medicine, Case Western Reserve University Cleveland OH"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6859-1191","authenticated-orcid":false,"given":"Tarek","family":"Chami","sequence":"additional","affiliation":[{"name":"Minneapolis Heart Institute Minneapolis MN"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6578-1926","authenticated-orcid":false,"given":"Haytham","family":"Mously","sequence":"additional","affiliation":[{"name":"Harrington Heart and Vascular Institute University Hospitals and School of Medicine, Case Western Reserve University Cleveland OH"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jamal","family":"Hajjari","sequence":"additional","affiliation":[{"name":"Department of Medicine University Hospitals Cleveland OH"},{"name":"Harrington Heart and Vascular Institute University Hospitals and School of Medicine, Case Western Reserve University Cleveland 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