{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T04:28:29Z","timestamp":1784262509798,"version":"3.55.0"},"reference-count":30,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"10","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2022,5,17]]},"abstract":"<jats:sec xml:lang=\"en\">\n            <jats:title>Background<\/jats:title>\n            <jats:p xml:lang=\"en\">Prolonged exposure to a hemodynamically significant patent ductus arteriosus (PDA) is associated with major morbidity, particularly in infants born at &lt;27\u00a0weeks\u2019 gestation. High\u2010frequency jet ventilation (HFJV) is a standard of care at our center. There are no data about transcatheter PDA closure while on HFJV. The aim of this study was to assess the feasibility, safety, and outcomes of HFJV during transcatheter PDA closure.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Methods and Results<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              This is a retrospective cohort study of premature infants undergoing transcatheter device closure on HFJV. The primary outcome was successful device placement. Secondary outcomes included procedure time, fluoroscopy time and dose, time off unit, device complications, need for escalation in respiratory support, and 7\u2010day survival. Subgroup comparative evaluation of patients managed with HFJV versus a small cohort of patients managed with conventional mechanical ventilation was performed. Thirty\u2010eight patients were included in the study. Median age and median weight at PDA device closure for the HFJV cohort were 32\u00a0days (interquartile range, 25.25\u201342.0\u00a0days) and 1115 g (interquartile range, 885\u20131310 g), respectively. There was successful device placement in 100% of patients. There were no device complications noted. The time off unit and the procedure time were not significantly different between the HFJV group and the conventional ventilation group. Infants managed by HFJV had shorter median fluoroscopy times (4.5 versus 6.1\u00a0minutes;\n              <jats:italic>P<\/jats:italic>\n              &lt;0.05) and no increased risk of adverse respiratory outcomes.\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p xml:lang=\"en\">Transcatheter PDA closure in premature infants on HFJV is a safe and effective approach that does not compromise device placement success rate and does not lead to secondary complications.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/jaha.122.025343","type":"journal-article","created":{"date-parts":[[2022,5,16]],"date-time":"2022-05-16T09:15:29Z","timestamp":1652692529000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":13,"title":["Feasibility, Safety, and Short\u2010Term Outcomes of Transcatheter Patent Ductus Arteriosus Closure in Premature Infants on High\u2010Frequency Jet Ventilation"],"prefix":"10.1161","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2644-5425","authenticated-orcid":false,"given":"Kamel","family":"Shibbani","sequence":"first","affiliation":[{"name":"Division of Pediatric Cardiology Stead Family Children\u2019s Hospital University of Iowa Iowa City IA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0811-446X","authenticated-orcid":false,"given":"Bassel","family":"Mohammad Nijres","sequence":"additional","affiliation":[{"name":"Division of Pediatric Cardiology Stead Family Children\u2019s Hospital University of Iowa Iowa City IA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2545-1241","authenticated-orcid":false,"given":"Daniel","family":"McLennan","sequence":"additional","affiliation":[{"name":"Division of Pediatric Cardiology Stead Family Children\u2019s Hospital University of Iowa Iowa City IA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9218-1301","authenticated-orcid":false,"given":"Adrianne Rahde","family":"Bischoff","sequence":"additional","affiliation":[{"name":"Division of Neonatology Stead Family Children\u2019s Hospital University of Iowa Iowa City IA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6227-6761","authenticated-orcid":false,"given":"Regan","family":"Giesinger","sequence":"additional","affiliation":[{"name":"Division of Neonatology Stead Family Children\u2019s Hospital University of Iowa Iowa City IA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7648-8872","authenticated-orcid":false,"given":"Patrick J.","family":"McNamara","sequence":"additional","affiliation":[{"name":"Division of Pediatric Cardiology Stead Family Children\u2019s Hospital University of Iowa Iowa City IA"},{"name":"Division 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