{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T21:08:56Z","timestamp":1793653736097,"version":"4.5.1"},"reference-count":19,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"8","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2023,4,18]]},"abstract":"<jats:sec sec-type=\"background\" xml:lang=\"en\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p xml:lang=\"en\">The impact of home monitoring on unanticipated interstage readmissions in infants with hypoplastic left heart syndrome has not been previously studied. We sought to examine the association of our institution's Infant Single Ventricle Management and Monitoring Program (ISVMP) with readmission frequency, cumulative readmission days, and readmission illness severity and to identify patient\u2010level risk factors for readmission.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Methods and Results<\/jats:title>\n                    <jats:p xml:lang=\"en\">\n                      We performed a retrospective single\u2010center cohort study comparing infants with hypoplastic left heart syndrome enrolled in ISVMP (December 2010\u2013December 2019) to historical controls (January 2007\u2013November 2010). The primary outcome was number of readmissions per interstage days. Secondary outcomes were cumulative interstage readmission days and occurrence of severe readmissions. Inverse probability weighted and multivariable generalized linear models were used to examine the association between ISVMP and the outcomes. We compared 198 infants in the ISVMP to 128 historical controls. Infants in the ISVMP had more than double the risk of interstage readmission compared with controls (adjusted incidence rate ratio, 2.38 [95% CI, 1.50\u20133.78];\n                      <jats:italic>P<\/jats:italic>\n                      =0.0003). There was no difference in cumulative interstage readmission days (adjusted incidence rate ratio, 1.02 [95% CI, 0.69\u20131.50];\n                      <jats:italic>P<\/jats:italic>\n                      =0.90); however, infants in the ISVMP were less likely to have severe readmissions (adjusted odds ratio, 0.28 [95% CI, 0.11\u20130.68];\n                      <jats:italic>P<\/jats:italic>\n                      =0.005). Other factors independently associated with number of readmissions included residing closer to our center, younger gestational age, genetic syndrome, and discharge on exclusive enteral feeds.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p xml:lang=\"en\">Infants in the ISVMP had more frequent readmissions but comparable readmission days and fewer severe unanticipated readmissions. These findings suggest that home monitoring can reduce interstage morbidity without increasing readmission days.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/jaha.122.025686","type":"journal-article","created":{"date-parts":[[2023,4,17]],"date-time":"2023-04-17T05:12:54Z","timestamp":1681708374000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":5,"title":["Association of Home Monitoring and Unanticipated Interstage Readmissions in Infants With Hypoplastic Left Heart Syndrome"],"prefix":"10.1161","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2177-3032","authenticated-orcid":false,"given":"Rachel J.","family":"Shustak","sequence":"first","affiliation":[{"name":"Division of Cardiology, Department of Pediatrics, The Children\u2019s Hospital of Philadelphia and Perelman School of Medicine University of Pennsylvania Philadelphia PA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8019-0646","authenticated-orcid":false,"given":"Jennifer A.","family":"Faerber","sequence":"additional","affiliation":[{"name":"Department of Biomedical and Health Informatics, Data Science and Biostatistics Unit The Children\u2019s Hospital of Philadelphia Philadelphia PA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alyson","family":"Stagg","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Pediatrics, The Children\u2019s Hospital of Philadelphia and Perelman School of Medicine University of Pennsylvania Philadelphia PA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David A.","family":"Hehir","sequence":"additional","affiliation":[{"name":"Division of Cardiac Critical Care Medicine, The Children\u2019s Hospital of Philadelphia and Department of Anesthesiology and Critical Care Perelman School of Medicine at the University of Pennsylvania Philadelphia PA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shobha S.","family":"Natarajan","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Pediatrics, The Children\u2019s Hospital of Philadelphia and Perelman School of Medicine University of Pennsylvania Philadelphia PA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tamar J.","family":"Preminger","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Pediatrics, The Children\u2019s Hospital of Philadelphia and Perelman School of Medicine University of Pennsylvania Philadelphia PA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8734-6447","authenticated-orcid":false,"given":"Anita","family":"Szwast","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Pediatrics, The Children\u2019s Hospital of Philadelphia and Perelman School of Medicine University of Pennsylvania Philadelphia PA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7362-0935","authenticated-orcid":false,"given":"Jonathan J.","family":"Rome","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Pediatrics, The Children\u2019s Hospital of Philadelphia and Perelman School of Medicine University of Pennsylvania Philadelphia PA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Therese M.","family":"Giglia","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Pediatrics, The Children\u2019s Hospital of Philadelphia and Perelman School of Medicine University of Pennsylvania Philadelphia PA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chitra","family":"Ravishankar","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Pediatrics, The Children\u2019s Hospital of Philadelphia and Perelman School of Medicine University of Pennsylvania Philadelphia PA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2170-5942","authenticated-orcid":false,"given":"Laura","family":"Mercer\u2010Rosa","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Pediatrics, The Children\u2019s Hospital of Philadelphia and Perelman School of Medicine University of Pennsylvania Philadelphia PA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3656-3561","authenticated-orcid":false,"given":"Monique M.","family":"Gardner","sequence":"additional","affiliation":[{"name":"Division of Cardiac Critical Care Medicine, The Children\u2019s Hospital of Philadelphia and Department of Anesthesiology and Critical Care Perelman School of Medicine at the University of Pennsylvania Philadelphia PA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.119.014548"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2009.07.063"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCOUTCOMES.115.001956"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.pcsu.2004.02.017"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(03)00071-0"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.118.010783"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.semtcvs.2016.08.011"},{"key":"e_1_3_1_9_2","doi-asserted-by":"publisher","DOI":"10.1177\/2150135118762401"},{"key":"e_1_3_1_10_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.semtcvs.2016.10.016"},{"key":"e_1_3_1_11_2","doi-asserted-by":"publisher","DOI":"10.1080\/00273171.2011.568786"},{"key":"e_1_3_1_12_2","doi-asserted-by":"publisher","DOI":"10.1177\/2150135118815023"},{"key":"e_1_3_1_13_2","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.120.016889"},{"key":"e_1_3_1_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1010-7940(02)00198-7"},{"key":"e_1_3_1_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2012.05.020"},{"key":"e_1_3_1_16_2","doi-asserted-by":"publisher","DOI":"10.1017\/S1047951113000127"},{"key":"e_1_3_1_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2011.12.027"},{"key":"e_1_3_1_18_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2011-3114"},{"key":"e_1_3_1_19_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-015-1241-2"},{"key":"e_1_3_1_20_2","doi-asserted-by":"publisher","DOI":"10.1214\/17-aoas1101"}],"container-title":["Journal 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