{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:55:04Z","timestamp":1787018104397,"version":"build-2736575974"},"reference-count":22,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2023,3,21]]},"abstract":"<jats:sec sec-type=\"background\" xml:lang=\"en\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p xml:lang=\"en\">Following myocardial infarction, left ventricular remodeling (LVR) is associated with heart failure and cardiac death. At the same time, left atrial (LA) remodeling (LAR) is an essential part of the outcome of a wide spectrum of cardiac conditions. The authors sought to evaluate the correlates of LAR and its relationships with LVR after myocardial infarction.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Methods and Results<\/jats:title>\n                    <jats:p xml:lang=\"en\">\n                      This is a retrospective analysis of 320 of 443 patients enrolled for study of LVR after ST\u2010elevation myocardial infarction. Left ventricular (LV) volumes, infarct size and LA volume index were assessed by cardiac magnetic resonance imaging during index hospitalization (day 6 [interquartile range, 4\u20138]) and after a 3\u2010month follow\u2010up. LAR was studied using a linear mixed model for repeated measurements. Overall, there was a decrease in LA volume index between 6\u2009days and 3\u2009months (43.9\u00b110.4\u2009mL versus 42.8\u00b111.1\u2009mL,\n                      <jats:italic>P<\/jats:italic>\n                      =0.003). Patients with changes in LA volume index &gt;8% over time were older, with greater body mass index, lower LV ejection fraction, and larger infarct size. Unadjusted predictors of LAR were age older than 70\u2009years, infarct size, anterior infarction, time to reperfusion, history of hypertension, LV end\u2010diastolic volume, and heart failure at day 6. Independent correlates were age older than 70\u2009years (3.24\u00b11.33,\n                      <jats:italic>P<\/jats:italic>\n                      =0.015) and infarct size (2.16\u00b10.72 per 10% LV,\n                      <jats:italic>P<\/jats:italic>\n                      &lt;0.001). LA remodeling was correlated with LV remodeling (\n                      <jats:italic>r<\/jats:italic>\n                      =0.372,\n                      <jats:italic>P<\/jats:italic>\n                      &lt;0.001), but neither LA nor LV volumes at day 6 were related to LVR or LAR, respectively.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p xml:lang=\"en\">The authors found LA changes to occur in the months after myocardial infarction, with an overall decrease in LA volumes. While LAR coincided with LVR, the correlates for LAR were age older than 70\u2009years and larger infarct size.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/jaha.122.026048","type":"journal-article","created":{"date-parts":[[2023,3,16]],"date-time":"2023-03-16T21:59:42Z","timestamp":1679003982000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":8,"title":["Left Atrial Remodeling Following ST\u2010Segment\u2013Elevation Myocardial Infarction Correlates With Infarct Size and Age Older Than 70\u2009Years"],"prefix":"10.1161","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5459-4890","authenticated-orcid":false,"given":"Adrien","family":"Pascaud","sequence":"first","affiliation":[{"name":"Institut Mitovasc, UMR CNRS 6015\u2010INSERMU1083, University of Angers Angers France"},{"name":"Department of Cardiology University Hospital of Angers Angers France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2567-017X","authenticated-orcid":false,"suffix":"Jr","given":"Antonildes","family":"Assun\u00e7\u00e3o","sequence":"additional","affiliation":[{"name":"Heart Institute, InCor University of Sao Paulo Medical School Sao Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0381-2501","authenticated-orcid":false,"given":"Gabriel","family":"Garcia","sequence":"additional","affiliation":[{"name":"Institut Mitovasc, UMR CNRS 6015\u2010INSERMU1083, University of Angers Angers France"},{"name":"Department of Cardiology University Hospital of Angers Angers France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eloi","family":"Vacher","sequence":"additional","affiliation":[{"name":"Institut Mitovasc, UMR CNRS 6015\u2010INSERMU1083, University of Angers Angers France"},{"name":"Department of Cardiology University Hospital of Angers Angers France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Serge","family":"Willoteaux","sequence":"additional","affiliation":[{"name":"Institut Mitovasc, UMR CNRS 6015\u2010INSERMU1083, University of Angers Angers France"},{"name":"Department of Radiology, University Hospital of Angers Angers France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6637-1141","authenticated-orcid":false,"given":"Fabrice","family":"Prunier","sequence":"additional","affiliation":[{"name":"Institut Mitovasc, UMR CNRS 6015\u2010INSERMU1083, University of Angers Angers France"},{"name":"Department of Cardiology University Hospital of Angers Angers France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5918-0419","authenticated-orcid":false,"given":"Alain","family":"Furber","sequence":"additional","affiliation":[{"name":"Institut Mitovasc, UMR CNRS 6015\u2010INSERMU1083, University of Angers Angers France"},{"name":"Department of Cardiology University Hospital of Angers Angers France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9321-3739","authenticated-orcid":false,"given":"Lo\u00efc","family":"Bi\u00e8re","sequence":"additional","affiliation":[{"name":"Institut Mitovasc, UMR CNRS 6015\u2010INSERMU1083, University of Angers Angers France"},{"name":"Department of Cardiology University Hospital of Angers Angers France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(99)00630-0"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(01)01319-5"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12968-018-0517-0"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2006.02.048"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2005.05.031"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2016.05.017"},{"key":"e_1_3_1_8_2","first-page":"228","article-title":"Dynamic changes of edema and late gadolinium enhancement after acute myocardial infarction and their relationship to functional recovery and salvage index","volume":"4","author":"Dall'Armellina E","year":"2011","unstructured":"Dall'Armellina E, Karia N, Lindsay AC, Karamitsos TD, Ferreira V, Robson MD, Kellman P, Francis JM, Forfar C, Prendergast BD, et al. 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