{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T19:49:10Z","timestamp":1791920950350,"version":"4.3.4"},"reference-count":32,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"18","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2022,9,20]]},"abstract":"<jats:sec sec-type=\"background\" xml:lang=\"en\">\n            <jats:title>Background<\/jats:title>\n            <jats:p xml:lang=\"en\">A history of preeclampsia is associated with increased risk of coronary artery disease and experimental evidence suggests that a history of preeclampsia also increases the risk of restenosis. However, the extent to which a history of preeclampsia is associated with risk of restenosis after percutaneous coronary intervention in women is unknown.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Methods and Results<\/jats:title>\n            <jats:p xml:lang=\"en\">We included 6065 parous women aged \u226465\u2009years with first percutaneous coronary intervention on 9452 segments 2006 to 2017, linking nationwide data on percutaneous coronary intervention and delivery history in Sweden. Main outcomes were clinical restenosis and target lesion revascularization within 2\u2009years. We accounted for segment\u2010, procedure\u2010, and patient\u2010related potential predictors of restenosis in proportional hazards regression models. Restenosis occurred in 345 segments (3.7%) and target lesion revascularization was performed on 383 patients (6.3%). A history of preeclampsia was neither significantly associated with risk of restenosis (predictor\u2010accounted hazard ratio [HR], 0.71 [95% CI, 0.41\u20131.23]) nor target lesion revascularization (0.74 [95% CI, 0.51\u20131.07]) compared with a normotensive pregnancy history. When term and preterm preeclampsia were investigated separately, segments in women with a history of term preeclampsia had a lower risk of restenosis (predictor\u2010accounted HR, 0.45 [95% CI, 0.21\u20130.94]). A history of preeclampsia was not significantly associated with death by any cause within 2\u2009years of the index procedure (predictor\u2010accounted HR 1.06, [95% CI, 0.62\u20131.80]).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p xml:lang=\"en\">A history of preeclampsia was not associated with increased risk of restenosis but instead some evidence pointed to a decreased risk. To facilitate future studies and allow for replication, concomitant collection of data on pregnancy complication history and percutaneous coronary intervention outcomes in women is warranted.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/jaha.122.026287","type":"journal-article","created":{"date-parts":[[2022,9,8]],"date-time":"2022-09-08T10:39:42Z","timestamp":1662633582000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Coronary Artery Restenosis in Women by History of Preeclampsia"],"prefix":"10.1161","volume":"11","author":[{"given":"Annie","family":"Lin","sequence":"first","affiliation":[{"name":"Perinatal and Cardiovascular Epidemiology Lund University Diabetes Centre, Clinical Sciences Malm\u00f6, Lund University Malm\u00f6 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moa","family":"Pehrson","sequence":"additional","affiliation":[{"name":"Perinatal and Cardiovascular Epidemiology Lund University Diabetes Centre, Clinical Sciences Malm\u00f6, Lund University Malm\u00f6 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanna","family":"Sarno","sequence":"additional","affiliation":[{"name":"Department of Medical Sciences Cardiology and Uppsala Clinical Research Center, Uppsala University Uppsala Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7741-9470","authenticated-orcid":false,"given":"Abigail","family":"Fraser","sequence":"additional","affiliation":[{"name":"Population Health Science, Bristol Medical School University of Bristol Bristol United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janet W.","family":"Rich\u2010Edwards","sequence":"additional","affiliation":[{"name":"Division of Women\u2019s Health Department of Medicine, Brigham and Women\u2019s Hospital and Harvard Medical School Boston MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabel","family":"Gon\u04abalves","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Cardiovascular Research Translational Studies Clinical Sciences Malm\u00f6, Lund University Malm\u00f6 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mats","family":"Pihlsg\u00e5rd","sequence":"additional","affiliation":[{"name":"Perinatal and Cardiovascular Epidemiology Lund University Diabetes Centre, Clinical Sciences Malm\u00f6, Lund University Malm\u00f6 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7445-7212","authenticated-orcid":false,"given":"Simon","family":"Timpka","sequence":"additional","affiliation":[{"name":"Perinatal and Cardiovascular Epidemiology Lund University Diabetes Centre, Clinical Sciences Malm\u00f6, Lund University Malm\u00f6 Sweden"},{"name":"Department of Obstetrics and Gynecology Sk\u00e5ne University Hospital Malm\u00f6 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.21037\/jtd.2016.10.93"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.118.007023"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2020.08.002"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2020.01.056"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2016.09.052"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.118.038080"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12170-019-0616-y"},{"key":"e_1_3_1_9_2","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.114.04971"},{"key":"e_1_3_1_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2015.08.021"},{"key":"e_1_3_1_11_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.118.313276"},{"key":"e_1_3_1_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/jog.12825"},{"key":"e_1_3_1_13_2","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/9548612"},{"key":"e_1_3_1_14_2","doi-asserted-by":"publisher","DOI":"10.1177\/140349489001800209"},{"key":"e_1_3_1_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2009.01.054"},{"key":"e_1_3_1_16_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehr479"},{"key":"e_1_3_1_17_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.l2381"},{"key":"e_1_3_1_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2013.12.008"},{"key":"e_1_3_1_19_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa031884"},{"key":"e_1_3_1_20_2","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.120.14860"},{"key":"e_1_3_1_21_2","doi-asserted-by":"publisher","DOI":"10.1503\/cmaj.202837"},{"key":"e_1_3_1_22_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.116.308366"},{"key":"e_1_3_1_23_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehy275"},{"key":"e_1_3_1_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2011.05.011"},{"key":"e_1_3_1_25_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.120.052766"},{"key":"e_1_3_1_26_2","doi-asserted-by":"publisher","DOI":"10.1177\/1933719110366164"},{"key":"e_1_3_1_27_2","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.113.03058"},{"key":"e_1_3_1_28_2","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.114.03200"},{"key":"e_1_3_1_29_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2018.02.023"},{"key":"e_1_3_1_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2017.02.001"},{"key":"e_1_3_1_31_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehy394"},{"key":"e_1_3_1_32_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCOUTCOMES.115.002482"},{"key":"e_1_3_1_33_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.113.003901"}],"container-title":["Journal of the American Heart Association"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/JAHA.122.026287","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T12:26:35Z","timestamp":1715603195000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/JAHA.122.026287"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,20]]},"references-count":32,"journal-issue":{"issue":"18","published-print":{"date-parts":[[2022,9,20]]}},"alternative-id":["10.1161\/JAHA.122.026287"],"URL":"https:\/\/doi.org\/10.1161\/jaha.122.026287","relation":{},"ISSN":["2047-9980"],"issn-type":[{"value":"2047-9980","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,9,20]]},"assertion":[{"value":"2022-03-29","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-08-02","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-09-08","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e026287"}}