{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T17:00:08Z","timestamp":1791910808352,"version":"4.3.4"},"reference-count":25,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"19","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2022,10,4]]},"abstract":"<jats:sec sec-type=\"background\" xml:lang=\"en\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p xml:lang=\"en\">Intracoronary imaging (ICI) has been shown to improve survival after percutaneous coronary intervention (PCI). Whether this prognostic benefit is sustained across different indications remains unclear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Methods and Results<\/jats:title>\n                    <jats:p xml:lang=\"en\">All PCI procedures performed in England and Wales between April, 2014 and March 31, 2020, were retrospectively analyzed. The association between ICI use and in\u2010hospital major acute cardiovascular and cerebrovascular events; composite of all\u2010cause mortality, stroke, and reinfarction and mortality was examined using multivariable logistic regression analysis for different imaging\u2010recommended indications as set by European Association for Percutaneous Cardiovascular Interventions consensus. Of 555\u2009398 PCI procedures, 10.8% (n=59\u2009752) were ICI\u2010guided. ICI use doubled between 2014 (7.8%) and 2020 (17.5%) and was highest in left main PCI (41.2%) and lowest in acute coronary syndrome (9%). Only specific European Association for Percutaneous Cardiovascular Interventions imaging\u2010recommended indications were associated with reduced major acute cardiovascular and cerebrovascular events and mortality, including left main PCI (odds ratio [OR], 0.45 [95% CI, 0.39\u20130.52] and 0.41 [95% CI, 0.35\u20130.48], respectively), acute coronary syndrome (OR, 0.76 [95% CI, 0.70\u20130.82] and 0.70 [95% CI, 0.63\u20130.77]), and stent length &gt;60\u2009mm (OR, 0.75 [95% CI, 0.59\u20130.94] and 0.72 [95% CI, 0.54\u20130.95]). Stent thrombosis and renal failure were associated with lower mortality (OR, 0.69 [95% CI, 0.52\u20130.91]) and major acute cardiovascular and cerebrovascular events (OR, 0.77 [95% CI, 0.60\u20130.99]), respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p xml:lang=\"en\">ICI use has more than doubled over a 7\u2010year period at a national level but remains low, with &lt;1 in 5 procedures performed under ICI guidance. In\u2010hospital survival was better with ICI\u2010guided than angiography\u2010guided PCI, albeit only for specific indications.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/jaha.122.026500","type":"journal-article","created":{"date-parts":[[2022,9,29]],"date-time":"2022-09-29T05:45:16Z","timestamp":1664430316000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":14,"title":["Impact of Intracoronary Imaging\u2010Guided Percutaneous Coronary Intervention on Procedural Outcomes Among Complex Patient Groups"],"prefix":"10.1161","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9678-5222","authenticated-orcid":false,"given":"Mohamed O.","family":"Mohamed","sequence":"first","affiliation":[{"name":"Keele Cardiovascular Research Group, Centre for Prognosis Research Keele University United Kingdom"},{"name":"Institute of Health Informatics University College London London United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1209-3534","authenticated-orcid":false,"given":"Tim","family":"Kinnaird","sequence":"additional","affiliation":[{"name":"Department of Cardiology University Hospital Wales Wales"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8464-1080","authenticated-orcid":false,"given":"Harindra C.","family":"Wijeysundera","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Cardiology University of Toronto Toronto Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4638-601X","authenticated-orcid":false,"given":"Thomas W.","family":"Johnson","sequence":"additional","affiliation":[{"name":"Bristol Heart Institute University of Bristol United 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