{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T17:25:49Z","timestamp":1781717149636,"version":"3.54.5"},"reference-count":28,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"11","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2023,6,6]]},"abstract":"<jats:sec id=\"jah38488-sec-0001\" sec-type=\"background\" xml:lang=\"en\">\n            <jats:title>Background<\/jats:title>\n            <jats:p xml:lang=\"en\">No data currently exist comparing the contemporary iterations of balloon\u2010expandable (BE) Edwards SAPIEN 3\/Ultra and the self\u2010expanding (SE) Medtronic Evolut PRO\/R34 valves. The aim of the study was the comparison of these transcatheter heart valves with emphasis on patients with small aortic annulus.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec id=\"jah38488-sec-0002\" xml:lang=\"en\">\n            <jats:title>Methods and Results<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              In this retrospective registry, periprocedural outcomes and midterm all\u2010cause mortality were analyzed. A total of 1673 patients (917 SE versus 756 BE) were followed up for a median of 15\u2009months. A total of 194 patients died (11.6%) during follow\u2010up. SE and BE groups showed similar survival at 1 (92.6% versus 90.6%) and 3 (80.3% versus 85.2%) years (\n              <jats:italic toggle=\"no\">P<\/jats:italic>\n              <jats:sub>log\u2010rank<\/jats:sub>\n              =0.136).\n            <\/jats:p>\n            <jats:p xml:lang=\"en\">\n              Compared with the BE group, patients treated with the SE device had lower peak (16.3\u00b18\u2009mm\u2009Hg SE versus 21.9\u00b18\u2009mm\u2009Hg BE) and mean (8.8\u00b15\u2009mm\u2009Hg SE versus 11.5\u00b15\u2009mm\u2009Hg BE) gradients at discharge. Conversely, the BE group demonstrated lower rates of at least moderate paravalvular regurgitation postoperatively (5.6% versus 0.7% for SE and BE valves, respectively;\n              <jats:italic toggle=\"no\">P<\/jats:italic>\n              &lt;0.001). In patients treated with small transcatheter heart valves (\u226426\u2009mm for SE and \u226423\u2009mm for BE; N=284 for SE and N=260 for BE), survival was higher among patients treated with SE valves at both 1 (96.7% SE versus 92.1% BE) and 3 (91.8% SE versus 82.2% BE) years (\n              <jats:italic toggle=\"no\">P<\/jats:italic>\n              <jats:sub>log\u2010rank<\/jats:sub>\n              =0.042). In propensity\u2010matched patients treated with small transcatheter heart valve, there remained a trend for higher survival among the SE group at both 1 (97% SE versus 92.3% BE) and 3 years (91.8% SE versus 78.7% BE),\n              <jats:italic toggle=\"yes\">P<\/jats:italic>\n              <jats:sub>log\u2010rank<\/jats:sub>\n              =0.096).\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec id=\"jah38488-sec-0003\" xml:lang=\"en\">\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p xml:lang=\"en\">Real\u2010world comparison of the latest\u2010generation SE and BE devices demonstrated similar survival up to 3\u2009years\u2019 follow\u2010up. In patients with small transcatheter heart valves, there may be a trend for improved survival among those treated with SE valves.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/jaha.122.028038","type":"journal-article","created":{"date-parts":[[2023,5,26]],"date-time":"2023-05-26T09:30:11Z","timestamp":1685093411000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":14,"title":["Midterm Outcomes in Patients With Aortic Stenosis Treated With Contemporary Balloon\u2010Expandable and Self\u2010Expanding Valves: Does Valve Size Have an Impact on Outcome?"],"prefix":"10.1161","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2036-6192","authenticated-orcid":false,"given":"Konstantinos","family":"Kalogeras","sequence":"first","affiliation":[{"name":"Guy\u2019s and St Thomas\u2019 National Health Service Foundation Trust","place":["London, UK"]},{"name":"National and Kapodistrian University of 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