{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T02:26:53Z","timestamp":1791599213952,"version":"4.3.4"},"reference-count":48,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"9","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2023,5,2]]},"abstract":"<jats:sec sec-type=\"background\" xml:lang=\"en\">\n            <jats:title>Background<\/jats:title>\n            <jats:p xml:lang=\"en\">Although depression is well established as an independent risk factor for cardiovascular disease (CVD) in the nonpregnant population, this association has largely not been investigated in pregnant populations. We aimed to estimate the cumulative risk of new CVD in the first 24\u2009months postpartum among pregnant individuals diagnosed with prenatal depression compared with patients without depression diagnosed during pregnancy.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Methods and Results<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              Our longitudinal population\u2010based study included pregnant individuals with deliveries during 2007 to 2019 in the Maine Health Data Organization's All Payer Claims Data. We excluded those with prepregnancy CVD, multifetal gestations, or no continuous health insurance during pregnancy. Prenatal depression and CVD (heart failure, ischemic heart disease, arrhythmia\/cardiac arrest, cardiomyopathy, cerebrovascular disease, and chronic hypertension) were identified by\n              <jats:italic>International Classification of Diseases, Ninth Revision<\/jats:italic>\n              (\n              <jats:italic>ICD\u20109<\/jats:italic>\n              )\/\n              <jats:italic>International Classification of Diseases, Tenth Revision<\/jats:italic>\n              (\n              <jats:italic>ICD\u201010<\/jats:italic>\n              ) codes. Cox models were used to estimate hazard ratios (HRs), adjusting for potential confounding factors. Analyses were stratified by hypertensive disorder of pregnancy. A total of 119\u2009422 pregnancies were examined. Pregnant individuals with prenatal depression had an increased risk of ischemic heart disease, arrhythmia\/cardiac arrest, cardiomyopathy, and new hypertension (adjusted HR [aHR], 1.83 [95% CI, 1.20\u20132.80], aHR, 1.60 [95% CI, 1.10\u20132.31], aHR, 1.61 [95% CI, 1.15\u20132.24], and aHR, 1.32 [95% CI, 1.17\u20131.50], respectively). When the analyses were stratified by co\u2010occurring hypertensive disorders of pregnancy, several of these associations persisted.\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p xml:lang=\"en\">The cumulative risk of a new CVD diagnosis postpartum was elevated among individuals with prenatal depression and persists even in the absence of co\u2010occurring hypertensive disorders of pregnancy. Further research to determine the causal pathway can inform postpartum CVD preventive measures.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/jaha.122.028133","type":"journal-article","created":{"date-parts":[[2023,4,19]],"date-time":"2023-04-19T10:08:09Z","timestamp":1681898889000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":31,"title":["Association of Prenatal Depression With New Cardiovascular Disease Within 24\u2009Months Postpartum"],"prefix":"10.1161","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2698-7395","authenticated-orcid":false,"given":"Christina M.","family":"Ackerman\u2010Banks","sequence":"first","affiliation":[{"name":"Yale School of Medicine New Haven CT"},{"name":"Baylor College of Medicine Houston TX"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heather S.","family":"Lipkind","sequence":"additional","affiliation":[{"name":"Yale School of Medicine New Haven CT"},{"name":"Cornell Medical College New York City NY"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0134-6228","authenticated-orcid":false,"given":"Kristin","family":"Palmsten","sequence":"additional","affiliation":[{"name":"Pregnancy and Child Health Research Center, Health Partners Institute Minneapolis MN"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3898-3597","authenticated-orcid":false,"given":"Mariah","family":"Pfeiffer","sequence":"additional","affiliation":[{"name":"Muskie School of Public Service University of Southern Maine Portland ME"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9845-6476","authenticated-orcid":false,"given":"Catherine","family":"Gelsinger","sequence":"additional","affiliation":[{"name":"Muskie School of Public Service University of Southern Maine Portland ME"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5139-9208","authenticated-orcid":false,"given":"Katherine A.","family":"Ahrens","sequence":"additional","affiliation":[{"name":"Muskie School of Public Service University of Southern Maine Portland ME"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(14)61682-2"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000485"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000002114"},{"key":"e_1_3_2_5_2","volume-title":"Pregnancy\u2010Related Deaths: Data from 14 US Maternal Mortality Review Committees, 2008\u20102017","author":"Davis NL","year":"2019","unstructured":"Davis NL, Smoots AN, Goodman DA. 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