{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T06:54:19Z","timestamp":1773298459135,"version":"3.50.1"},"reference-count":35,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2023,1,3]]},"abstract":"<jats:sec sec-type=\"background\" xml:lang=\"en\">\n            <jats:title>Background<\/jats:title>\n            <jats:p xml:lang=\"en\">Transcatheter aortic valve replacement (TAVR)\/intervention has become the standard of care for treatment of severe aortic stenosis across the spectrum of risk. There are socioeconomic disparities in access to TAVR. The impact of these disparities on postprocedural outcomes remains unknown. Our objective was to examine the association between neighborhood\u2010level social deprivation and post\u2010TAVR mortality and hospital readmission.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Methods and Results<\/jats:title>\n            <jats:p xml:lang=\"en\">We conducted a population\u2010based retrospective cohort study of all 4145 patients in Ontario, Canada, who received TAVR from April 1, 2017, to March 31, 2020. Our co\u2010primary outcomes were 1\u2010year postprocedure mortality and 1\u2010year postprocedure readmission. Using Cox proportional hazards models for mortality and cause\u2010specific competing risk hazard models for readmission, we evaluated the relationship between neighborhood\u2010level measures of residential instability, material deprivation, and concentration of racial and ethnic groups with post\u2010TAVR outcomes. After multivariable adjustment, we found a statistically significant relationship between residential instability and postprocedural 1\u2010year mortality, ranging from a hazard ratio of 1.64 to a hazard ratio of 2.05. There was a significant association between the highest degree of residential instability and 1\u2010year readmission (hazard ratio, 1.23 [95% CI, 1.01\u20131.49]). There was no association between material deprivation and concentration of racial and ethnic groups with post\u2010TAVR outcomes.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p xml:lang=\"en\">Residential instability was associated with increased risk for post\u2010TAVR mortality, and the highest quintile of residential instability was associated with increased post\u2010TAVR readmission. To reduce health disparities and promote an equitable health care system, further research and policy interventions will be required to identify and support economically and socially minoritized patients undergoing TAVR.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/jaha.122.028144","type":"journal-article","created":{"date-parts":[[2022,12,24]],"date-time":"2022-12-24T10:37:42Z","timestamp":1671878262000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":6,"title":["Social Deprivation and Post\u2010TAVR Outcomes in Ontario, Canada: A Population\u2010Based Study"],"prefix":"10.1161","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9547-9127","authenticated-orcid":false,"given":"Raumil V.","family":"Patel","sequence":"first","affiliation":[{"name":"Temerty Faculty of Medicine University of Toronto Ontario Toronto Canada"},{"name":"Institute for Health Policy, Management, and Evaluation Ontario Toronto 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