{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T22:12:22Z","timestamp":1791670342126,"version":"4.3.4"},"reference-count":36,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"7","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2023,4,4]]},"abstract":"<jats:sec sec-type=\"background\" xml:lang=\"en\">\n            <jats:title>Background<\/jats:title>\n            <jats:p xml:lang=\"en\">Various hemodynamic changes occur following transcatheter aortic valve implantation (TAVI) that may impact therapeutic decisions. NICaS is a noninvasive bioimpedance monitoring system aimed at hemodynamic assessment. We used the NICaS system in patients with severe aortic stenosis (AS) to evaluate short\u2010term hemodynamic changes after TAVI.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Methods and Results<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              We performed hemodynamic analysis using NICaS on 97 patients with severe AS who underwent TAVI using either self\u2010expandable (68%) or balloon\u2010expandable (32%) valves. Patients were more often women (54%) and had multiple comorbidities including hypertension (83%), coronary artery disease (46%), and diabetes (37%). NICaS was performed at several time points\u2014before TAVI, soon after TAVI, at hospital discharge, and during follow\u2010up. Compared with baseline NICaS measurements, we observed a significant increase in systolic blood pressure and total peripheral resistance (systolic blood pressure 132\u00b121\u2009mm\u2009Hg at baseline versus 147\u00b123\u2009mm\u2009Hg after TAVI,\n              <jats:italic>P<\/jats:italic>\n              &lt;0.001; total peripheral resistance 1751\u00b1512 versus 2084\u00b1762\u2009dynes*s\/cm\n              <jats:sup>5<\/jats:sup>\n              , respectively,\n              <jats:italic>P<\/jats:italic>\n              &lt;0.001) concurrent with a decrease in cardiac output and stroke volume (cardiac output 4.2\u00b11.5 versus 3.9\u00b11.3\u2009L\/min,\n              <jats:italic>P<\/jats:italic>\n              =0.037; stroke volume 61.4\u00b114.8 versus 56.2\u00b115.9\u2009mL,\n              <jats:italic>P<\/jats:italic>\n              =0.001) in the immediate post\u2010TAVI period. At follow\u2010up (median 59\u2009days [interquartile range, 40.5\u201391]) these measurements returned to values that were not different from the baseline. A significant improvement in echocardiography\u2010based left ventricular ejection fraction was observed from baseline to follow\u2010up (55.6%\u00b111.6% to 59.4%\u00b19.4%,\n              <jats:italic>P<\/jats:italic>\n              &lt;0.001).\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p xml:lang=\"en\">Unique short\u2010term adaptive hemodynamic changes were observed using NICaS in patients with AS soon after TAVI. Noninvasive hemodynamic evaluation immediately following TAVI may contribute to the understanding of complex hemodynamic changes and merits favorable consideration.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/jaha.122.028479","type":"journal-article","created":{"date-parts":[[2023,3,21]],"date-time":"2023-03-21T10:49:02Z","timestamp":1679395742000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":12,"title":["Noninvasive Hemodynamic Evaluation Following TAVI for Severe Aortic Stenosis"],"prefix":"10.1161","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7786-1886","authenticated-orcid":false,"given":"Tzlil","family":"Grinberg","sequence":"first","affiliation":[{"name":"Department of Cardiology Rabin Medical Center Petah Tikva Israel"},{"name":"The Faculty of Medicine Tel Aviv University Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8158-6802","authenticated-orcid":false,"given":"Yaron","family":"Aviv","sequence":"additional","affiliation":[{"name":"Department of Cardiology Rabin Medical Center Petah Tikva Israel"},{"name":"The Faculty of Medicine Tel Aviv University Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mordehay","family":"Vaturi","sequence":"additional","affiliation":[{"name":"Department of Cardiology Rabin Medical Center Petah Tikva Israel"},{"name":"The Faculty of Medicine Tel Aviv University Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0625-7937","authenticated-orcid":false,"given":"Leor","family":"Perl","sequence":"additional","affiliation":[{"name":"Department of Cardiology Rabin Medical Center Petah Tikva Israel"},{"name":"The Faculty of Medicine Tel Aviv University Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8044-7878","authenticated-orcid":false,"given":"Maya","family":"Wiessman","sequence":"additional","affiliation":[{"name":"Department of Cardiology Rabin Medical Center Petah Tikva Israel"},{"name":"The Faculty of Medicine Tel Aviv University Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanna","family":"Vaknin\u2010Assa","sequence":"additional","affiliation":[{"name":"Department of Cardiology Rabin Medical Center Petah Tikva Israel"},{"name":"The Faculty of Medicine Tel Aviv University Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pablo","family":"Codner","sequence":"additional","affiliation":[{"name":"Department of Cardiology Rabin Medical Center Petah Tikva Israel"},{"name":"The Faculty of Medicine Tel Aviv University Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaron","family":"Shapira","sequence":"additional","affiliation":[{"name":"Department of Cardiology Rabin Medical Center Petah Tikva Israel"},{"name":"The Faculty of Medicine Tel Aviv University Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7708-8253","authenticated-orcid":false,"given":"Ran","family":"Kornowski","sequence":"additional","affiliation":[{"name":"Department of Cardiology Rabin Medical Center Petah Tikva Israel"},{"name":"The Faculty of Medicine Tel Aviv University Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2523-6469","authenticated-orcid":false,"given":"Katia","family":"Orvin","sequence":"additional","affiliation":[{"name":"Department of Cardiology Rabin Medical Center Petah Tikva Israel"},{"name":"The Faculty of Medicine Tel Aviv University Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/cpf.12153"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2009.01.060"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2010.07.017"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2010.02.030"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2012.06.010"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2018.11.038"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2012.12.124"},{"key":"e_1_3_2_9_2","first-page":"675","article-title":"Post\u2010procedural arterial hypertension: implications for clinical outcome after transcatheter aortic valve implantation","volume":"23","author":"Reinthaler M","year":"2014","unstructured":"Reinthaler M, St\u00e4hli BE, Gopalamurugan AB, Xiu PY, Aggarwal SK, Fr\u00f6hlich G, Delahunty N, Mullen MJ. 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